D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 59 Citations 8,917 180 World Ranking 5770 National Ranking 118

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Cancer
  • Internal medicine

Tullio Florio mainly investigates Cell biology, Cancer research, Somatostatin, Somatostatin receptor and Internal medicine. His Cell biology research is multidisciplinary, relying on both Neuroglia, Biochemistry, Chemokine receptor and Astrocyte. His Cancer research study incorporates themes from Cancer stem cell, Protein kinase B, Signal transduction and Autocrine signalling.

His Cancer stem cell research integrates issues from Molecular biology, Pharmacology and Drug repositioning. As part of one scientific family, Tullio Florio deals mainly with the area of Somatostatin receptor, narrowing it down to issues related to the In vivo, and often In vitro and Neovascularization. Tullio Florio has included themes like Endocrinology and Cell growth in his Internal medicine study.

His most cited work include:

  • Chemokines and their receptors in the central nervous system. (328 citations)
  • Stromal Cell-derived Factor 1α Stimulates Human Glioblastoma Cell Growth through the Activation of Both Extracellular Signal-regulated Kinases 1/2 and Akt (309 citations)
  • Glial and neuronal cells express functional chemokine receptor CXCR4 and its natural ligand stromal cell-derived factor 1. (207 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Internal medicine, Endocrinology, Cancer research, Cell biology and Somatostatin. Tullio Florio regularly ties together related areas like Oncology in his Internal medicine studies. His biological study spans a wide range of topics, including Cell, Protein kinase B, Cell growth, Cellular differentiation and Cancer stem cell.

His Cell growth research incorporates themes from Cell culture and Cell cycle. His biological study deals with issues like Apoptosis, which deal with fields such as Molecular biology. His work on Somatostatin is being expanded to include thematically relevant topics such as Receptor.

He most often published in these fields:

  • Internal medicine (30.97%)
  • Endocrinology (28.36%)
  • Cancer research (26.49%)

What were the highlights of his more recent work (between 2014-2021)?

  • Cancer research (26.49%)
  • Cancer stem cell (14.93%)
  • Stem cell (9.70%)

In recent papers he was focusing on the following fields of study:

Tullio Florio spends much of his time researching Cancer research, Cancer stem cell, Stem cell, Cell biology and Cell growth. His research in Cancer research intersects with topics in Cell, Cellular differentiation, CXCR4, Neuroblastoma and In vivo. The study incorporates disciplines such as Cytotoxic T cell, Pituitary adenoma, SOX2, Cell cycle and Pharmacology in addition to Cancer stem cell.

His study in Stem cell is interdisciplinary in nature, drawing from both Bone marrow, Mesenchymal stem cell, Intracellular and Biguanide. His work on Progenitor cell as part of general Cell biology study is frequently linked to Membrane Transport Modulators, therefore connecting diverse disciplines of science. His Cell growth study combines topics from a wide range of disciplines, such as Cell culture, Gene knockdown, Non-coding RNA, Protein kinase B and Downregulation and upregulation.

Between 2014 and 2021, his most popular works were:

  • Chloride channels in cancer: Focus on chloride intracellular channel 1 and 4 (CLIC1 AND CLIC4) proteins in tumor development and as novel therapeutic targets ☆ (81 citations)
  • Drug-repositioning opportunities for cancer therapy: novel molecular targets for known compounds. (68 citations)
  • The histone demethylase KDM5A is a key factor for the resistance to temozolomide in glioblastoma (57 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • Amino acid

Tullio Florio mainly investigates Cancer stem cell, Cancer research, Stem cell, Cell biology and Cellular differentiation. His Cancer stem cell study integrates concerns from other disciplines, such as In vivo, Pathology, SOX2, Pharmacology and Drug discovery. His Cancer research research is multidisciplinary, incorporating perspectives in Protein kinase B, Cell growth, Progenitor cell, Immunology and Viability assay.

The Stem cell study combines topics in areas such as Cell and Mesenchymal stem cell. His research integrates issues of Autophagy and Programmed cell death in his study of Cell biology. His work carried out in the field of Cellular differentiation brings together such families of science as Cell cycle, Pituitary adenoma and Temozolomide.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Stromal Cell-derived Factor 1α Stimulates Human Glioblastoma Cell Growth through the Activation of Both Extracellular Signal-regulated Kinases 1/2 and Akt

Simone Barbero;Rudy Bonavia;Adriana Bajetto;Carola Porcile.
Cancer Research (2003)

454 Citations

Chemokines and their receptors in the central nervous system.

Adriana Bajetto;Rudy Bonavia;Simone Barbero;Tullio Florio.
Frontiers in Neuroendocrinology (2001)

451 Citations

Glial and neuronal cells express functional chemokine receptor CXCR4 and its natural ligand stromal cell-derived factor 1.

Adriana Bajetto;Rudy Bonavia;Simone Barbero;Patrizia Piccioli.
Journal of Neurochemistry (2002)

254 Citations

Octreotide, a somatostatin analogue, mediates its antiproliferative action in pituitary tumor cells by altering phosphatidylinositol 3-kinase signaling and inducing Zac1 expression.

Marily Theodoropoulou;Jing Zhang;Sandra Laupheimer;Marcelo Paez-Pereda.
Cancer Research (2006)

249 Citations

Stromal cell-derived factor-1α induces astrocyte proliferation through the activation of extracellular signal-regulated kinases 1/2 pathway

Adriana Bajetto;Simone Barbero;Rudy Bonavia;Patrizia Piccioli.
Journal of Neurochemistry (2001)

234 Citations

Stromal cell-derived factor-1α (SDF-1α/CXCL12) stimulates ovarian cancer cell growth through the EGF receptor transactivation

Carola Porcile;Adriana Bajetto;Federica Barbieri;Simone Barbero.
Experimental Cell Research (2005)

198 Citations

17A, a novel non-coding RNA, regulates GABA B alternative splicing and signaling in response to inflammatory stimuli and in Alzheimer disease

Sara Massone;Irene Vassallo;Gloria Fiorino;Manuele Castelnuovo.
Neurobiology of Disease (2011)

185 Citations

Somatostatin Activation of Mitogen-Activated Protein Kinase via Somatostatin Receptor 1 (SSTR1)

Tullio Florio;Hong Yao;Kendall D. Carey;Tara J. Dillon.
Molecular Endocrinology (1999)

182 Citations

Expression of CXC chemokine receptors 1-5 and their ligands in human glioma tissues: role of CXCR4 and SDF1 in glioma cell proliferation and migration.

Adriana Bajetto;Federica Barbieri;Alessandra Dorcaratto;Simone Barbero.
Neurochemistry International (2006)

173 Citations

Somatostatin Inhibits Tumor Angiogenesis and Growth via Somatostatin Receptor-3-Mediated Regulation of Endothelial Nitric Oxide Synthase and Mitogen-Activated Protein Kinase Activities

T. Florio;M. Morini;V. Villa;S. Arena.
Endocrinology (2003)

165 Citations

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