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Tullio Florio

Tullio Florio

D-Index & Metrics

Biology and Biochemistry

D-Index
72
Citations
25162
World Ranking
6165
National Ranking
144

Overview

Tullio Florio is affiliated with the University of Genoa in Italy. Their research spans multiple interconnected fields, with main areas of focus including Medicine and Biochemistry, Genetics and Molecular Biology. Within these broader fields, their work extensively covers molecular biology, cancer research, oncology, neurology, and genetics.

Their research topics specifically involve neuroblastoma treatments, metabolism related to diabetes and cancer, the interplay between cancer, hypoxia, and metabolism, extracellular vesicles in disease, microRNA's role in disease regulation, glioma diagnosis and treatment, as well as advances in neuroendocrine tumor research.

Key recent publications by Tullio Florio include:

  • Exosomes and Extracellular Vesicles as Emerging Theranostic Platforms in Cancer Research (2020) published in Cells
  • Cross talk between mesenchymal and glioblastoma stem cells: Communication beyond controversies (2020) published in Stem Cells Translational Medicine
  • Chloride intracellular channel 1 activity is not required for glioblastoma development but its inhibition dictates glioma stem cell responsivity to novel biguanide derivatives (2022) published in Journal of Experimental & Clinical Cancer Research
  • Metformin potentiates immunosuppressant activity and adipogenic differentiation of human umbilical cord-mesenchymal stem cells (2023) published in International Immunopharmacology
  • Boron Vehiculating Nanosystems for Neutron Capture Therapy in Cancer Treatment (2022) published in Cells

Frequent coauthors in Florio's publications include:

  • Federica Barbieri
  • Stefano Thellung
  • Adriana Bajetto
  • Aldo Pagano
  • Michele Mazzanti

The most common venues for their publications are:

  • Cancer Research
  • Frontiers in Endocrinology
  • International Journal of Molecular Sciences
  • Cells
  • Journal of Experimental & Clinical Cancer Research

Tullio Florio's contributions span multiple disciplines centered on molecular mechanisms and cancer biology, with significant work on extracellular vesicles and cellular activities influencing tumor development and treatment response.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

    Daniel J. Klionsky;Amal Kamal Abdel-Aziz;Sara Abdelfatah;Mahmoud Abdellatif

  • Chemokines and their receptors in the central nervous system.

    Adriana Bajetto;Rudy Bonavia;Simone Barbero;Tullio Florio

  • Stromal Cell-derived Factor 1α Stimulates Human Glioblastoma Cell Growth through the Activation of Both Extracellular Signal-regulated Kinases 1/2 and Akt

    Simone Barbero;Rudy Bonavia;Adriana Bajetto;Carola Porcile

  • Octreotide, a somatostatin analogue, mediates its antiproliferative action in pituitary tumor cells by altering phosphatidylinositol 3-kinase signaling and inducing Zac1 expression.

    Marily Theodoropoulou;Jing Zhang;Sandra Laupheimer;Marcelo Paez-Pereda

  • Glial and neuronal cells express functional chemokine receptor CXCR4 and its natural ligand stromal cell-derived factor 1.

    Adriana Bajetto;Rudy Bonavia;Simone Barbero;Patrizia Piccioli

  • G Protein Activation of a Hormone-Stimulated Phosphatase in Human Tumor Cells

    Ming Gui Pan;Tuillio Florio;Philip J. S. Stork

  • 17A, a novel non-coding RNA, regulates GABA B alternative splicing and signaling in response to inflammatory stimuli and in Alzheimer disease

    Sara Massone;Irene Vassallo;Gloria Fiorino;Manuele Castelnuovo

  • Stromal cell-derived factor-1α induces astrocyte proliferation through the activation of extracellular signal-regulated kinases 1/2 pathway

    Adriana Bajetto;Simone Barbero;Rudy Bonavia;Patrizia Piccioli

  • Somatostatin Inhibits Tumor Angiogenesis and Growth via Somatostatin Receptor-3-Mediated Regulation of Endothelial Nitric Oxide Synthase and Mitogen-Activated Protein Kinase Activities

    T. Florio;M. Morini;V. Villa;S. Arena

  • Stromal cell-derived factor-1α (SDF-1α/CXCL12) stimulates ovarian cancer cell growth through the EGF receptor transactivation

    Carola Porcile;Adriana Bajetto;Federica Barbieri;Simone Barbero

  • Metformin selectively affects human glioblastoma tumor-initiating cell viability: A role for metformin-induced inhibition of Akt.

    Roberto Würth;Alessandra Pattarozzi;Monica Gatti;Adirana Bajetto

  • CXCL12 modulation of CXCR4 and CXCR7 activity in human glioblastoma stem-like cells and regulation of the tumor microenvironment.

    Roberto Würth;Adriana Bajetto;Jeffrey K. Harrison;Federica Barbieri

  • Expression of CXC chemokine receptors 1-5 and their ligands in human glioma tissues: role of CXCR4 and SDF1 in glioma cell proliferation and migration.

    Adriana Bajetto;Federica Barbieri;Alessandra Dorcaratto;Simone Barbero

  • Somatostatin Activation of Mitogen-Activated Protein Kinase via Somatostatin Receptor 1 (SSTR1)

    Tullio Florio;Hong Yao;Kendall D. Carey;Tara J. Dillon

  • An intronic ncRNA-dependent regulation of SORL1 expression affecting Aβ formation is upregulated in post-mortem Alzheimer's disease brain samples

    Eleonora Ciarlo;Sara Massone;Ilaria Penna;Mario Nizzari

  • Molecular mechanisms of the antiproliferative activity of somatostatin receptors (SSTRs) in neuroendocrine tumors.

    Tullio Florio

  • Different Response of Human Glioma Tumor-initiating Cells to Epidermal Growth Factor Receptor Kinase Inhibitors

    Fabrizio Griffero;Antonio Daga;Daniela Marubbi;Maria Cristina Capra

  • Somatostatin controls Kaposi’s sarcoma tumor growth through inhibition of angiogenesis

    A. Albini;T. Florio;D. Giunciuglio;L. Masiello

  • EGFRvIII gene rearrangement is an early event in glioblastoma tumorigenesis and expression defines a hierarchy modulated by epigenetic mechanisms

    C A Del Vecchio;C P Giacomini;H Vogel;K C Jensen;K C Jensen

  • Drug-repositioning opportunities for cancer therapy: novel molecular targets for known compounds.

    Roberto Würth;Stefano Thellung;Adriana Bajetto;Michele Mazzanti

Frequent Co-Authors

Gennaro Schettini
Gennaro Schettini University of Genoa
Diego Ferone
Diego Ferone University of Genoa
Alfredo Fusco
Alfredo Fusco University of Naples Federico II
Ranieri Cancedda
Ranieri Cancedda University of Genoa
Gianluigi Forloni
Gianluigi Forloni Mario Negri Institute for Pharmacological Research
Mario Salmona
Mario Salmona Mario Negri Institute for Pharmacological Research
Fabrizio Tagliavini
Fabrizio Tagliavini Istituto Neurologico Carlo Besta
Philip J. S. Stork
Philip J. S. Stork Oregon Health & Science University
Giorgio Corte
Giorgio Corte University of Genoa
Alberto Diaspro
Alberto Diaspro Italian Institute of Technology

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