D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 53 Citations 14,777 96 World Ranking 11378 National Ranking 892

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

Stephen M. Keyse mostly deals with Biochemistry, Cell biology, Mitogen-activated protein kinase, MAPK/ERK pathway and Molecular biology. His study in Protein kinase A and MAP kinase phosphatase are all subfields of Cell biology. The concepts of his MAP kinase phosphatase study are interwoven with issues in MAPK7, MAPKAPK2, MAP kinase kinase kinase, MAP2K7 and ASK1.

As part of the same scientific family, Stephen M. Keyse usually focuses on Mitogen-activated protein kinase, concentrating on Dual-specificity phosphatase and intersecting with Signalling, Crosstalk and Tyrosine. In his study, which falls under the umbrella issue of MAPK/ERK pathway, p38 mitogen-activated protein kinases is strongly linked to DUSP6. His study in Molecular biology is interdisciplinary in nature, drawing from both Oxygenase, Heme oxygenase and Phosphatase.

His most cited work include:

  • Heme oxygenase is the major 32-kDa stress protein induced in human skin fibroblasts by UVA radiation, hydrogen peroxide, and sodium arsenite. (1122 citations)
  • Protein phosphatases and the regulation of mitogen-activated protein kinase signalling. (721 citations)
  • Differential regulation of MAP kinase signalling by dual-specificity protein phosphatases (612 citations)

What are the main themes of his work throughout his whole career to date?

Stephen M. Keyse mainly focuses on Cell biology, Molecular biology, Biochemistry, MAPK/ERK pathway and Mitogen-activated protein kinase. His work is dedicated to discovering how Molecular biology, Nucleotide excision repair are connected with Aphidicolin and Human skin and other disciplines. His work on Hydrogen peroxide, Heat shock protein, Oxidative stress and Saccharomyces cerevisiae as part of general Biochemistry research is often related to Nuclear export signal, thus linking different fields of science.

His work in MAPK/ERK pathway addresses issues such as Phosphatase, which are connected to fields such as Protein tyrosine phosphatase. His study looks at the relationship between Mitogen-activated protein kinase and fields such as Signalling, as well as how they intersect with chemical problems. His MAP kinase kinase kinase study combines topics in areas such as c-Raf, ASK1, Mitogen-activated protein kinase kinase and MAP2K7.

He most often published in these fields:

  • Cell biology (50.00%)
  • Molecular biology (31.91%)
  • Biochemistry (31.91%)

What were the highlights of his more recent work (between 2010-2019)?

  • Cell biology (50.00%)
  • MAPK/ERK pathway (29.79%)
  • Dual-specificity phosphatase (11.70%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Cell biology, MAPK/ERK pathway, Dual-specificity phosphatase, Mitogen-activated protein kinase and Kinase. His Cell biology and DUSP6, Mitogen-activated protein kinase kinase, MAP kinase kinase kinase and Phosphatase investigations all form part of his Cell biology research activities. The Mitogen-activated protein kinase kinase study combines topics in areas such as Cyclin-dependent kinase 2 and MAP2K7.

His MAPK/ERK pathway research is multidisciplinary, incorporating perspectives in Molecular biology and Protein kinase A. His research investigates the connection with Mitogen-activated protein kinase and areas like Signalling which intersect with concerns in Gene isoform, Crosstalk and MAP kinase phosphatase. His work on Receptor tyrosine kinase as part of general Kinase study is frequently linked to Oncogene, bridging the gap between disciplines.

Between 2010 and 2019, his most popular works were:

  • Dual-specificity MAP kinase phosphatases (MKPs): shaping the outcome of MAP kinase signalling. (318 citations)
  • The regulation of oncogenic Ras/ERK signalling by dual-specificity mitogen activated protein kinase phosphatases (MKPs). (115 citations)
  • Regulation of Caenorhabditis elegans p53/CEP-1-Dependent Germ Cell Apoptosis by Ras/MAPK Signaling (56 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

His scientific interests lie mostly in Cell biology, MAPK/ERK pathway, Dual-specificity phosphatase, Mitogen-activated protein kinase and DUSP6. Signal transduction is the focus of his Cell biology research. His MAPK/ERK pathway research incorporates elements of Caenorhabditis elegans and DNA damage.

The study incorporates disciplines such as Anti-apoptotic Ras signalling cascade, DMBA, Immunology and Ectopic expression in addition to Dual-specificity phosphatase. His Mitogen-activated protein kinase study is concerned with the field of Kinase as a whole. His biological study spans a wide range of topics, including Protein kinase A, Carcinogenesis, MAP kinase phosphatase, Signalling and Gene isoform.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Heme oxygenase is the major 32-kDa stress protein induced in human skin fibroblasts by UVA radiation, hydrogen peroxide, and sodium arsenite.

Stephen M. Keyse;Rex M. Tyrrell.
Proceedings of the National Academy of Sciences of the United States of America (1989)

1521 Citations

Protein phosphatases and the regulation of mitogen-activated protein kinase signalling.

Stephen M Keyse.
Current Opinion in Cell Biology (2000)

989 Citations

Differential regulation of MAP kinase signalling by dual-specificity protein phosphatases

D M Owens;S M Keyse.
Oncogene (2007)

877 Citations

Oxidative stress and heat shock induce a human gene encoding a protein-tyrosine phosphatase.

Stephen M. Keyse;Elizabeth A. Emslie.
Nature (1992)

766 Citations

Nuclear translocation of p42/p44 mitogen‐activated protein kinase is required for growth factor‐induced gene expression and cell cycle entry

Anne Brunet;Danièle Roux;Philippe Lenormand;Stephen Dowd.
The EMBO Journal (1999)

727 Citations

Dual-specificity MAP kinase phosphatases (MKPs) and cancer.

Stephen M. Keyse.
Cancer and Metastasis Reviews (2008)

523 Citations

Differential regulation of the MAP, SAP and RK/p38 kinases by Pyst1, a novel cytosolic dual-specificity phosphatase.

Linda A. Groom;Alan A. Sneddon;Dario R. Alessi;Stephen Dowd.
The EMBO Journal (1996)

464 Citations

Dual-specificity MAP kinase phosphatases (MKPs): shaping the outcome of MAP kinase signalling.

Christopher J. Caunt;Stephen M. Keyse.
FEBS Journal (2013)

461 Citations

Inactivation of p42 MAP kinase by protein phosphatase 2A and a protein tyrosine phosphatase, but not CL100, in various cell lines

Dario R. Alessi;Nestor Gomez;Greg Moorhead;Tom Lewis.
Current Biology (1995)

453 Citations

The human CL100 gene encodes a Tyr/Thr-protein phosphatase which potently and specifically inactivates MAP kinase and suppresses its activation by oncogenic ras in Xenopus oocyte extracts.

Alessi Dr;Smythe C;Keyse Sm.
Oncogene (1993)

432 Citations

If you think any of the details on this page are incorrect, let us know.

Contact us

Best Scientists Citing Stephen M. Keyse

Augustine M. K. Choi

Augustine M. K. Choi

Cornell University

Publications: 53

Stefan W. Ryter

Stefan W. Ryter

Cornell University

Publications: 35

Eisuke Nishida

Eisuke Nishida

Kyoto University

Publications: 31

Mahin D. Maines

Mahin D. Maines

University of Rochester

Publications: 30

Alan Wells

Alan Wells

University of Pittsburgh

Publications: 28

Ugo Moens

Ugo Moens

University of Tromsø - The Arctic University of Norway

Publications: 27

Matthias Gaestel

Matthias Gaestel

Hannover Medical School

Publications: 27

Zhong Yin Zhang

Zhong Yin Zhang

Purdue University West Lafayette

Publications: 24

Leo E. Otterbein

Leo E. Otterbein

Beth Israel Deaconess Medical Center

Publications: 24

Rony Seger

Rony Seger

Weizmann Institute of Science

Publications: 23

George Perry

George Perry

The University of Texas at San Antonio

Publications: 22

Anupam Agarwal

Anupam Agarwal

University of Alabama at Birmingham

Publications: 22

Jack E. Dixon

Jack E. Dixon

University of California, San Diego

Publications: 21

Jawed Alam

Jawed Alam

University Medical Center New Orleans

Publications: 21

Melanie H. Cobb

Melanie H. Cobb

The University of Texas Southwestern Medical Center

Publications: 18

Shigeki Shibahara

Shigeki Shibahara

Tohoku University

Publications: 18

Trending Scientists

Erik Learned-Miller

Erik Learned-Miller

University of Massachusetts Amherst

Benjamin Gebhart

Benjamin Gebhart

University of Pennsylvania

Fred Y. Hadaegh

Fred Y. Hadaegh

Jet Propulsion Lab

Xiaojun Peng

Xiaojun Peng

Dalian University of Technology

Mark A. Blitz

Mark A. Blitz

University of Leeds

David K. Lunt

David K. Lunt

Texas A&M University

Manfred W. Kilimann

Manfred W. Kilimann

Max Planck Society

J. Gregory Caporaso

J. Gregory Caporaso

Northern Arizona University

Letícia V. Costa-Lotufo

Letícia V. Costa-Lotufo

Universidade de São Paulo

Yasuo Ikeda

Yasuo Ikeda

Waseda University

Kangsen Mai

Kangsen Mai

Ocean University of China

J. Oberst

J. Oberst

German Aerospace Center

Anthony J. Gow

Anthony J. Gow

Cold Regions Research and Engineering Laboratory

Thomas J. O'Dell

Thomas J. O'Dell

University of California, Los Angeles

Bernhard Hemmer

Bernhard Hemmer

Technical University of Munich

Madhav V. Dhodapkar

Madhav V. Dhodapkar

Emory University

Something went wrong. Please try again later.