World's Best Scientists 2026 revealed!

Overview

Shih-Hsiung Wu is affiliated with the University of Wisconsin--Madison in the United States and specializes primarily in Biochemistry, Genetics and Molecular Biology. Their research spans 37 publications within this main field, with focused expertise in subfields such as Molecular Biology, Pharmacology, Organic Chemistry, Electrical and Electronic Engineering, and Materials Chemistry.

The scientist's work addresses a variety of topics including:

  • Glycosylation and Glycoproteins Research
  • Carbohydrate Chemistry and Synthesis
  • Microbial Natural Products and Biosynthesis
  • Fungal Biology and Applications
  • Antibiotic Resistance in Bacteria
  • Bacteriophages and microbial interactions
  • Marine Sponges and Natural Products

Several recent papers reflect these research interests. Among them are:

  • "Cyanine dye mediated mitochondrial targeting enhances the anti-cancer activity of small-molecule cargoes" (2020), published in Chemical Communications
  • "Development of Klebsiella pneumoniae Capsule Polysaccharide-Conjugated Vaccine Candidates Using Phage Depolymerases" (2022), published in Frontiers in Immunology
  • "Peptidomic analysis of low molecular weight antioxidative peptides prepared by lotus (Nelumbo nucifera Gaertn.) seed protein hydrolysates" (2021), published in LWT
  • "Structural and biological insights into Klebsiella pneumoniae surface polysaccharide degradation by a bacteriophage K1 lyase: implications for clinical use" (2022), published in Journal of Biomedical Science
  • "Effect of carbon and nitrogen sources on the production and carbohydrate composition of exopolysaccharide by submerged culture of pleurotus citrinopileatus" (2020), published in Journal of Food and Drug Analysis

Frequent publication venues indicate a diverse dissemination of research findings. These venues include:

  • Chemical Communications
  • Organic Electronics
  • Scientific Reports
  • The Cambridge Structural Database
  • Marine Drugs

Wu collaborates extensively with a core group of coauthors, reflecting ongoing partnerships in their research endeavors. Frequent collaborators include:

  • Feng-Ling Yang
  • Tzu-Yin Huang
  • Shu-Jung Lai
  • I-Ming Lee
  • Jyh-Horng Sheu

Best Publications

  • Quantitative analyses of biochemical kinetic resolution of enantiomers. 2. Enzyme-catalyzed esterifications in water-organic solvent biphasic systems

    Ching Shih Chen;Shih Hsiung Wu;Gary Girdaukas;Charles J. Sih

  • Structural and DNA-binding studies on the bovine antimicrobial peptide, indolicidin: evidence for multiple conformations involved in binding to membranes and DNA

    Chun-Hua Hsu;Chinpan Chen;Maou-Lin Jou;Alan Yueh-Luen Lee

  • Resolution of enantiomers via biocatalysis

    Charles J. Sih;Shih‐Hsiung Wu

  • Enhancing the enantioselectivity of Candida lipase-catalyzed ester hydrolysis via noncovalent enzyme modification

    Shih Hsiung Wu;Zhi Wei Guo;Charles J. Sih

  • The Flexible and Clustered Lysine Residues of Human Ribonuclease 7 Are Critical for Membrane Permeability and Antimicrobial Activity

    Yu-Chie Huang;Yu-Chie Huang;Yu-Min Lin;Yu-Min Lin;Ting-Wei Chang;Ting-Wei Chang;Shih-Jung Wu

  • Phosphoproteomics of Klebsiella pneumoniae NTUH-K2044 Reveals a Tight Link between Tyrosine Phosphorylation and Virulence

    Miao Hsia Lin;Tung Li Hsu;Shu Yu Lin;Yi Jiun Pan

  • Asperjinone, a nor-neolignan, and terrein, a suppressor of ABCG2-expressing breast cancer cells, from thermophilic Aspergillus terreus.

    Wen-Ying Liao;Chia-Ning Shen;Li-Hua Lin;Yu-Liang Yang

  • Sequential biocatalytic kinetic resolutions

    Zhi Wei Guo;Shih Hsiung Wu;Ching Shih Chen;Gary Girdaukas

  • Synthesis of sialyl Lewis X mimetics and related structures using the glycosyl phosphite methodology and evaluation of E-selectin inhibition

    Chun Cheng Lin;Makoto Shimazaki;Marie Pierre Heck;Shin Aoki

  • Rubrobacter taiwanensis sp. nov., a novel thermophilic, radiation-resistant species isolated from hot springs.

    Mao Yen Chen;Shih Hsiung Wu;Guang Huey Lin;Chun Ping Lu

  • Efficient and Stereoselective Synthesis of α(2→9) Oligosialic Acids: From Monomers to Dodecamers†

    Kuo-Ching Chu;Chien-Tai Ren;Chun-Ping Lu;Che-Hsiung Hsu;Che-Hsiung Hsu

  • Nitrophenylboronic acids as highly chemoselective probes to detect hydrogen peroxide in foods and agricultural products.

    C. P. Lu;C. T. Lin;C. M. Chang;S. H. Wu

  • Functional domains of Brevibacillus thermoruber lon protease for oligomerization and DNA binding: role of N-terminal and sensor and substrate discrimination domains.

    Alan Yueh-Luen Lee;Chun-Hua Hsu;Shih-Hsiung Wu;Shih-Hsiung Wu

  • Cloning, Sequencing, Heterologous Expression, Purification, and Characterization of Adenosylcobalamin-dependentd-Ornithine Aminomutase from Clostridium sticklandii

    Hao-Ping Chen;Shih-Hsiung Wu;Ya-Lin Lin;Chih-Ming Chen

  • Structure of human erythrocyte catalase.

    T.-P. Ko;M.K. Safo;F.N. Musayev;M.L. Di Salvo

  • Solution structure of a Kunitz-type chymotrypsin inhibitor isolated from the elapid snake Bungarus fasciatus.

    Chinpan Chen;Chun-Hua Hsu;Chun-Hua Hsu;Ning-Yuan Su;Yu-Ching Lin

  • Cytotoxic Polyketides Containing Tetramic Acid Moieties Isolated from the Fungus Myceliophthora Thermophila: Elucidation of the Relationship between Cytotoxicity and Stereoconfiguration

    Yu Liang Yang;Chun Ping Lu;Chun Ping Lu;Mao Yen Chen;Kuei Yu Chen

  • Design of a mechanism-based probe for neuraminidase to capture influenza viruses.

    Chun-Ping Lu;Chien-Tai Ren;Yi-Ning Lai;Shih-Hsiung Wu;Shih-Hsiung Wu

  • A novel exopolysaccharide from the biofilm of thermus aquaticus YT-1 induces the Immune response through toll-like receptor 2

    Miao-Hsia Lin;Yu-Liang Yang;Yen-Po Chen;Kuo-Feng Hua

  • Isolation and characterization of an active compound from black soybean [Glycine max (L.) Merr.] and its effect on proliferation and differentiation of human leukemic U937 cells.

    Hui-Fen Liao;Cheng-Jen Chou;Shih-Hsiung Wu;Kay-Hooi Khoo

Frequent Co-Authors

Shui-Tein Chen
Shui-Tein Chen Academia Sinica
Jin-Town Wang
Jin-Town Wang National Taiwan University
Charles J. Sih
Charles J. Sih University of Wisconsin–Madison
Kay-Hooi Khoo
Kay-Hooi Khoo National Taiwan University
Jyh-Horng Sheu
Jyh-Horng Sheu National Sun Yat-sen University
Jim-Min Fang
Jim-Min Fang National Taiwan University
Yang Chang Wu
Yang Chang Wu China Medical University
Chung-Yi Wu
Chung-Yi Wu Academia Sinica
Harold J. Jennings
Harold J. Jennings National Academies of Sciences, Engineering, and Medicine
Chun-Cheng Lin
Chun-Cheng Lin National Tsing Hua University

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