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Medicine

D-Index
91
Citations
31955
World Ranking
11717
National Ranking
32

Overview

Se-Hoon Lee is affiliated with Sungkyunkwan University in South Korea and has a primary research focus in the field of Medicine. Their work spans several subfields including Oncology, Pulmonary and Respiratory Medicine, Cancer Research, Radiology, Nuclear Medicine and Imaging, and Molecular Biology.

Their research concentrates on key topics such as:

  • Lung Cancer Treatments and Mutations
  • Cancer Immunotherapy and Biomarkers
  • Cancer Genomics and Diagnostics
  • Lung Cancer Research Studies
  • Radiomics and Machine Learning in Medical Imaging
  • Lung Cancer Diagnosis and Treatment
  • Colorectal Cancer Treatments and Studies

Se-Hoon Lee has contributed to numerous publications, frequently appearing in the following venues:

  • Journal of Clinical Oncology
  • Cancer Research
  • Cancer Research and Treatment
  • Journal of Thoracic Oncology
  • bioRxiv (Cold Spring Harbor Laboratory)

Their recent papers include:

  • Single-cell RNA sequencing demonstrates the molecular and cellular reprogramming of metastatic lung adenocarcinoma (2020, Nature Communications)
  • Randomized Phase III KEYNOTE-181 Study of Pembrolizumab Versus Chemotherapy in Advanced Esophageal Cancer (2020, Journal of Clinical Oncology)
  • Perioperative Pembrolizumab for Early-Stage Non-Small-Cell Lung Cancer (2023, New England Journal of Medicine)
  • Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition (2021, Cell)
  • Lung adenocarcinoma promotion by air pollutants (2023, Nature)

Frequent co-authors collaborating with Se-Hoon Lee include:

  • Myung-Ju Ahn
  • Hyun Ae Jung
  • Jin Seok Ahn
  • Keunchil Park
  • Jong-Mu Sun

This body of work reflects ongoing research into cancer treatment mechanisms, lung cancer pathology, and advanced approaches in immunotherapy and molecular diagnostics.

Best Publications

  • Antitumor Activity of Pembrolizumab in Biomarker-Unselected Patients With Recurrent and/or Metastatic Head and Neck Squamous Cell Carcinoma: Results From the Phase Ib KEYNOTE-012 Expansion Cohort

    Laura Q.M. Chow;Robert Haddad;Shilpa Gupta;Amit Mahipal

  • Randomized Phase III KEYNOTE-181 Study of Pembrolizumab Versus Chemotherapy in Advanced Esophageal Cancer

    Takashi Kojima;Manish A Shah;Kei Muro;Eric Francois

  • Meta-analysis of tumor- and T cell-intrinsic mechanisms of sensitization to checkpoint inhibition

    Kevin Litchfield;Kevin Litchfield;James L. Reading;Clare Puttick;Krupa Thakkar;Krupa Thakkar

  • Single-cell RNA sequencing demonstrates the molecular and cellular reprogramming of metastatic lung adenocarcinoma.

    Nayoung Kim;Nayoung Kim;Nayoung Kim;Hong Kwan Kim;Kyungjong Lee;Yourae Hong;Yourae Hong

  • Safety and efficacy of sunitinib for metastatic renal-cell carcinoma: an expanded-access trial

    Martin E Gore;Cezary Szczylik;Camillo Porta;Sergio Bracarda

  • The transcriptional landscape and mutational profile of lung adenocarcinoma

    Jeong Sun Seo;Young Seok Ju;Won Chul Lee;Jong Yeon Shin

  • Clonal History and Genetic Predictors of Transformation Into Small-Cell Carcinomas From Lung Adenocarcinomas.

    June Koo Lee;Junehawk Lee;Sehui Kim;Soyeon Kim

  • Safety and Antitumor Activity of Pembrolizumab in Patients With Programmed Death-Ligand 1-Positive Nasopharyngeal Carcinoma: Results of the KEYNOTE-028 Study.

    Chiun Hsu;Se-Hoon Lee;Samuel Ejadi;Caroline Even

  • An observational study suggesting clinical benefit for adjuvant postoperative chemoradiation in a population of over 500 cases after gastric resection with D2 nodal dissection for adenocarcinoma of the stomach.

    Sung Kim;Do Hoon Lim;Jeeyun Lee;Won Ki Kang

  • DNA methylation loss promotes immune evasion of tumours with high mutation and copy number load

    Hyunchul Jung;Hong Sook Kim;Jeong Yeon Kim;Jong-Mu Sun

  • Functional analysis of receptor tyrosine kinase mutations in lung cancer identifies oncogenic extracellular domain mutations of ERBB2

    Heidi Greulich;Bethany Kaplan;Philipp Mertins;Tzu-Hsiu Chen

  • Osimertinib for Patients With Non–Small-Cell Lung Cancer Harboring Uncommon EGFR Mutations: A Multicenter, Open-Label, Phase II Trial (KCSG-LU15-09)

    Jang Ho Cho;Sung Hee Lim;Ho Jung An;Ki Hwan Kim

  • Ki-67 can be used for further classification of triple negative breast cancer into two subtypes with different response and prognosis.

    Bhumsuk Keam;Seock-Ah Im;Kyung-Hun Lee;Sae-Won Han

  • Pembrolizumab for Patients With Refractory or Relapsed Thymic Epithelial Tumor: An Open-Label Phase II Trial

    Jinhyun Cho;Hae Su Kim;Bo Mi Ku;Yoon-La Choi

  • Increased Response Rates to Salvage Chemotherapy Administered after PD-1/PD-L1 Inhibitors in Patients with Non–Small Cell Lung Cancer

    Song Ee Park;Se Hoon Lee;Jin Seok Ahn;Myung Ju Ahn

  • Alectinib versus crizotinib in untreated Asian patients with anaplastic lymphoma kinase-positive non-small-cell lung cancer (ALESIA): a randomised phase 3 study.

    Caicun Zhou;Sang We Kim;Thanyanan Reungwetwattana;Jianying Zhou

  • Vandetanib in pretreated patients with advanced non-small cell lung cancer-harboring RET rearrangement: a phase II clinical trial

    Se Hoon Lee;J. K. Lee;M. J. Ahn;D. W. Kim

  • Phase II study of oxaliplatin, 5-fluorouracil and leucovorin in previously platinum-treated patients with advanced gastric cancer

    D. Y. Kim;Joo Hang Kim;S. H. Lee;T. Y. Kim

  • Mechanisms of Acquired Resistance to AZD9291: A Mutation-Selective, Irreversible EGFR Inhibitor.

    Tae Min Kim;Tae Min Kim;Ahnah Song;Dong-Wan Kim;Dong-Wan Kim;Soyeon Kim

  • Extranodal nasal type NK/T-cell lymphoma: elucidating clinical prognostic factors for risk-based stratification of therapy.

    Jeeyun Lee;Yeon Hee Park;Won Seog Kim;Seung-Sook Lee

Frequent Co-Authors

Dae Seog Heo
Dae Seog Heo Seoul National University Hospital
Dong-Wan Kim
Dong-Wan Kim Seoul National University Hospital
Keunchil Park
Keunchil Park The University of Texas MD Anderson Cancer Center
Myung-Ju Ahn
Myung-Ju Ahn Sungkyunkwan University
Jin Seok Ahn
Jin Seok Ahn Sungkyunkwan University
Yung-Jue Bang
Yung-Jue Bang Seoul National University
Seock-Ah Im
Seock-Ah Im Seoul National University Hospital
Woong-Yang Park
Woong-Yang Park Samsung Medical Center
Doo Hyun Chung
Doo Hyun Chung Seoul National University
Ki-Hyun Kim
Ki-Hyun Kim Hanyang University

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