D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Chemistry D-index 46 Citations 6,989 283 World Ranking 12398 National Ranking 3373

Research.com Recognitions

Awards & Achievements

1994 - Fellow of the Royal Society, United Kingdom

Overview

What is he best known for?

The fields of study he is best known for:

  • Organic chemistry
  • Catalysis
  • Stereochemistry

Raymond Baker mainly focuses on Stereochemistry, Receptor, Bicyclic molecule, NMDA receptor and Glycine. His Stereochemistry study combines topics in areas such as Agonist, Antagonist, Potency, Ring and Alkyl. As a part of the same scientific study, Raymond Baker usually deals with the Receptor, concentrating on Imidazole and frequently concerns with Triazole, Tetrazole and Diazepam.

His Bicyclic molecule study combines topics from a wide range of disciplines, such as Biological activity, Heptane, Steric effects and Amine gas treating. The study incorporates disciplines such as Glycine receptor and Glycine binding in addition to NMDA receptor. His Carbon atom research focuses on Senile dementia and how it relates to Substituent and Medicinal chemistry.

His most cited work include:

  • 4-Amido-2-carboxytetrahydroquinolines. Structure-activity relationships for antagonism at the glycine site of the NMDA receptor. (162 citations)
  • Novel 5-HT3 antagonists. Indole oxadiazoles. (147 citations)
  • Novel quinuclidine-based ligands for the muscarinic cholinergic receptor (135 citations)

What are the main themes of his work throughout his whole career to date?

Raymond Baker spends much of his time researching Stereochemistry, Organic chemistry, Medicinal chemistry, Receptor and Ring. His study looks at the relationship between Stereochemistry and fields such as Alkyl, as well as how they intersect with chemical problems. Morpholine, Catalysis, Acetal, Aldehyde and Epoxide are the subjects of his Organic chemistry studies.

His Medicinal chemistry research is multidisciplinary, incorporating perspectives in Yield, Adduct, Allene and Nickel. While the research belongs to areas of Receptor, he spends his time largely on the problem of Triazole, intersecting his research to questions surrounding Sulphate salt, Ethylamine and Combinatorial chemistry. Raymond Baker studies Ring, focusing on Carbon atom in particular.

He most often published in these fields:

  • Stereochemistry (43.18%)
  • Organic chemistry (26.30%)
  • Medicinal chemistry (16.63%)

What were the highlights of his more recent work (between 1995-2010)?

  • Pharmacology (8.44%)
  • Stereochemistry (43.18%)
  • NK 1 Receptor Antagonists (3.97%)

In recent papers he was focusing on the following fields of study:

Pharmacology, Stereochemistry, NK 1 Receptor Antagonists, Morpholine and Receptor are his primary areas of study. His study in Pharmacology is interdisciplinary in nature, drawing from both Tachykinin receptor and Receptor antagonist. His research in Stereochemistry focuses on subjects like Lithium amide, which are connected to Furan.

The concepts of his Morpholine study are interwoven with issues in Scientific method, Prodrug and Halogen. Within one scientific family, Raymond Baker focuses on topics pertaining to Moiety under Receptor, and may sometimes address concerns connected to Bicyclic molecule, Cholecystokinin B receptor and Biological activity. In his study, Alkoxy group is inextricably linked to Ring, which falls within the broad field of Medicinal chemistry.

Between 1995 and 2010, his most popular works were:

  • Effect of plasma protein binding on in vivo activity and brain penetration of glycine/NMDA receptor antagonists. (122 citations)
  • 5-(4-Chlorophenyl)-4-methyl-3-(1-(2-phenylethyl)piperidin-4-yl)isoxazole: a potent, selective antagonist at human cloned dopamine D4 receptors. (87 citations)
  • 4-substituted-3-phenylquinolin-2(1H)-ones: acidic and nonacidic glycine site N-methyl-D-aspartate antagonists with in vivo activity. (57 citations)

In his most recent research, the most cited papers focused on:

  • Organic chemistry
  • Catalysis
  • Enzyme

His main research concerns Stereochemistry, Pharmacology, Receptor, Orally active and Receptor antagonist. His studies deal with areas such as Heteroatom, Alkyl and Chemical synthesis as well as Stereochemistry. Raymond Baker combines subjects such as Prodrug and Halogen with his study of Heteroatom.

His Chemical synthesis research is multidisciplinary, incorporating elements of NMDA receptor, Glycine and Antagonist. His Plasma protein binding study in the realm of Pharmacology interacts with subjects such as Postherpetic neuralgia. His work is dedicated to discovering how Receptor, Dopamine are connected with Combinatorial chemistry, In vitro, Isoxazole, Selective antagonist and Biochemistry and other disciplines.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

4-Amido-2-carboxytetrahydroquinolines. Structure-activity relationships for antagonism at the glycine site of the NMDA receptor.

P D Leeson;R W Carling;K W Moore;A M Moseley.
Journal of Medicinal Chemistry (1992)

250 Citations

Novel 5-HT3 antagonists. Indole oxadiazoles.

C. J. Swain;R. Baker;C. Kneen;J. Moseley.
Journal of Medicinal Chemistry (1991)

237 Citations

Novel quinuclidine-based ligands for the muscarinic cholinergic receptor

John Saunders;Mark Cassidy;Stephen B. Freedman;Elizabeth A. Harley.
Journal of Medicinal Chemistry (1990)

223 Citations

Kynurenic acid derivatives. Structure-activity relationships for excitatory amino acid antagonism and identification of potent and selective antagonists at the glycine site on the N-methyl-D-aspartate receptor.

Paul D. Leeson;Raymond Baker;Robert W. Carling;Neil R. Curtis.
Journal of Medicinal Chemistry (1991)

208 Citations

Total Synthesis and Determination of the Absolute Configuration of Epibatidine

Stephen R. Fletcher;Raymond Baker;Mark S. Chambers;Richard H. Herbert.
Journal of Organic Chemistry (1994)

190 Citations

Novel benzodiazepine receptor partial agonists: oxadiazolylimidazobenzodiazepines.

Frank Watjen;Raymond Baker;Mogens Engelstoff;Richard Herbert.
Journal of Medicinal Chemistry (1989)

188 Citations

Imidazole, triazole and tetrazole derivatives

Raymond Baker;Victor G. Matassa;Leslie J. Street.
(1993)

183 Citations

Substituted morpholine derivatives and their use as therapeutic agents

Raymond Baker;Timothy Harrison;Angus Murray Macleod;Andrew Pate Owens.
(1994)

182 Citations

Total synthesis of (+)-macbecin I

Raymond Baker;Jose L. Castro.
Journal of The Chemical Society-perkin Transactions 1 (1990)

175 Citations

Effect of plasma protein binding on in vivo activity and brain penetration of glycine/NMDA receptor antagonists.

Michael Rowley;Janusz J. Kulagowski;Alan P. Watt;Denise Rathbone.
Journal of Medicinal Chemistry (1997)

169 Citations

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