World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
55
Citations
19922
World Ranking
14761
National Ranking
6169

Overview

Pumin Zhang is affiliated with Baylor College of Medicine in the United States. Their research primarily focuses on the fields of biochemistry, genetics, and molecular biology, with significant contributions to medicine. The scientist's work spans to subfields including molecular biology, oncology, genetics, cell biology, and cardiology and cardiovascular medicine.

The main topics in Zhang's research include ubiquitin and proteasome pathways, DNA repair mechanisms, peptidase inhibition and analysis, CAR-T cell therapy research, cancer-related molecular pathways, PARP inhibition in cancer therapy, and nanowire synthesis and applications.

Frequent collaborators in Zhang's publications include Xinghua Zhen, Jin Peng, Lingzhi Wu, Huailu Ma, and Jiewei Wang.

Zhang has published multiple papers in prominent journals. Selected recent papers include:

  • "USP25 regulates KEAP1-NRF2 anti-oxidation axis and its inactivation protects acetaminophen-induced liver injury in male mice," 2023, Nature Communications
  • "Identification of a class of potent USP25/28 inhibitors with broad-spectrum anti-cancer activity," 2022, Signal Transduction and Targeted Therapy
  • "Ubiquitin-specific protease 28 deubiquitinates TCF7L2 to govern the action of the Wnt signaling pathway in hepatic carcinoma," 2022, Cancer Science
  • "Resistance and recurrence of malignancies after CAR-T cell therapy," 2021, Experimental Cell Research
  • "Functional Phosphoproteomics in Cancer Chemoresistance Using CRISPR-Mediated Base Editors," 2022, Advanced Science

Zhang's frequent publication venues encompass the Journal of Biological Chemistry, Advanced Science, Blood, Cancer Research, and Nature Communications.

Best Publications

  • Mice Lacking p21CIP1/WAF1 undergo normal development, but are defective in G1 checkpoint control

    Chuxia Deng;Chuxia Deng;Pumin Zhang;J. Wade Harper;Stephen J. Elledge;Stephen J. Elledge

  • Inhibition of cyclin-dependent kinases by p21.

    J W Harper;S J Elledge;K Keyomarsi;B Dynlacht

  • p57KIP2, a structurally distinct member of the p21CIP1 Cdk inhibitor family, is a candidate tumor suppressor gene.

    S Matsuoka;M C Edwards;C Bai;S Parker

  • P53-independent expression of p21Cip1 in muscle and other terminally differentiating cells

    S. B. Parker;G. Eichele;Pumin Zhang;A. Rawls

  • FTO Plays an Oncogenic Role in Acute Myeloid Leukemia as a N 6-Methyladenosine RNA Demethylase

    Zejuan Li;Hengyou Weng;Hengyou Weng;Rui Su;Xiaocheng Weng;Xiaocheng Weng

  • Altered cell differentiation and proliferation in mice lacking p57 KIP2 indicates a role in Beckwith–Wiedemann syndrome

    Pumin Zhang;Nanette J. Liégeois;Calvin Wong;Milton Finegold

  • Generation of gene-modified mice via Cas9/RNA-mediated gene targeting.

    Bin Shen;Jun Zhang;Hongya Wu;Jianying Wang

  • The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C

    Valeria Facchinetti;Weiming Ouyang;Hua Wei;Nelyn Soto

  • p21CIP1 and p57KIP2 control muscle differentiation at the myogenin step

    Pumin Zhang;C. Wong;Dou Liu;M. Finegold

  • Acetylation of Smc3 by Eco1 Is Required for S Phase Sister Chromatid Cohesion in Both Human and Yeast

    Jinglan Zhang;Xiaomin Shi;Yehua Li;Beom-Jun Kim

  • Cooperation between the Cdk inhibitors p27KIP1 and p57KIP2 in the control of tissue growth and development

    Pumin Zhang;Calvin Wong;Ronald A. DePinho;J. Wade Harper

  • Defective cardiovascular development and elevated cyclin E and Notch proteins in mice lacking the Fbw7 F-box protein

    Michael T. Tetzlaff;Wei Yu;Mamie Li;Pumin Zhang

  • The ATM–p53 pathway suppresses aneuploidy-induced tumorigenesis

    Min Li;Xiao Fang;Darren J. Baker;Linjie Guo

  • Temporal Differences in Granulosa Cell Specification in the Ovary Reflect Distinct Follicle Fates in Mice

    Lindsey Mork;Danielle M. Maatouk;Jill A. McMahon;Jin Jin Guo

  • Fat Mass and Obesity-associated (FTO) Protein Regulates Adult Neurogenesis.

    Liping Li;Liping Li;Liqun Zang;Liqun Zang;Feiran Zhang;Junchen Chen;Junchen Chen

  • GUDMAP: The Genitourinary Developmental Molecular Anatomy Project

    Andrew P. McMahon;Bruce J. Aronow;Duncan R. Davidson;Jamie A. Davies

  • The fat mass and obesity associated gene FTO functions in the brain to regulate postnatal growth in mice.

    Xue Gao;Yong Hyun Shin;Min Li;Fei Wang

  • Stella safeguards the oocyte methylome by preventing de novo methylation mediated by DNMT1

    Yingfeng Li;Yingfeng Li;Zhuqiang Zhang;Jiayu Chen;Wenqiang Liu

  • The adaptor protein of the anaphase promoting complex Cdh1 is essential in maintaining replicative lifespan and in learning and memory

    Min Li;Yong Hyun Shin;Lingfei Hou;Xingxu Huang

  • Heat- and anesthesia-induced malignant hyperthermia in an RyR1 knock-in mouse

    Mihail G. Chelu;Sanjeewa A. Goonasekera;William J. Durham;Wei Tang

Frequent Co-Authors

Stephen J. Elledge
Stephen J. Elledge Harvard University
Xingxu Huang
Xingxu Huang First Affiliated Hospital Zhejiang University
Fuchu He
Fuchu He Beijing Proteome Research Center
Jianping Jin
Jianping Jin Zhejiang University
Melissa H. Little
Melissa H. Little Murdoch Children's Research Institute
Jianjun Chen
Jianjun Chen University of Cincinnati
Jiemin Wong
Jiemin Wong East China Normal University
J. Wade Harper
J. Wade Harper Harvard Medical School
Yang Xia
Yang Xia The University of Texas Health Science Center at Houston
Jun Qin
Jun Qin Baylor College of Medicine

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