His primary areas of study are Cell biology, Syndecan 1, Cartilage, Biochemistry and Molecular biology. His Cell biology research is multidisciplinary, relying on both Embryonic stem cell, Ectoderm and Mesoderm. His research integrates issues of Cancer research, Fibrosis, Pathology, Muscular dystrophy and MyoD Protein in his study of Syndecan 1.
His work on Proteochondroitin Sulfate, Perichondrium and Chondrocyte is typically connected to Aggrecan as part of general Cartilage study, connecting several disciplines of science. He combines subjects such as Regeneration and Skeletal muscle with his study of Biochemistry. His study in Fibronectin is interdisciplinary in nature, drawing from both Integrin and Focal adhesion.
Paul F. Goetinck spends much of his time researching Cell biology, Biochemistry, Cartilage, Proteoglycan and Molecular biology. Paul F. Goetinck has included themes like Syndecan 1 and Anatomy in his Cell biology study. His Syndecan 1 research incorporates elements of Integrin, Internal medicine, Endocrinology and Pathology.
His Biochemistry study which covers Hyaluronic acid that intersects with Cartilaginous Tissue and Extracellular. His research in Cartilage tackles topics such as Mutant which are related to areas like Biophysics. His biological study spans a wide range of topics, including Embryonic stem cell, Antiserum, Gene expression and Chondroitin sulfate.
The scientist’s investigation covers issues in Cell biology, Syndecan 1, Internal medicine, Endocrinology and Pathology. Many of his studies involve connections with topics such as Dermis and Cell biology. His work carried out in the field of Syndecan 1 brings together such families of science as Cancer research, Integrin, Host resistance, NFAT Pathway and Fibrosis.
His Internal medicine study incorporates themes from Extracellular matrix and Signal transduction, MAPK/ERK pathway. As part of one scientific family, he deals mainly with the area of Phosphorylation, narrowing it down to issues related to the Molecular biology, and often Psoriasis and Immunoelectron microscopy. His Fibronectin research is multidisciplinary, incorporating perspectives in Granulation tissue and Receptor tyrosine kinase.
Paul F. Goetinck focuses on Cell biology, Syndecan 1, Pathology, Tyrosine kinase and Fibronectin. His research on Cell biology often connects related topics like Cell adhesion. Syndecan 1 is a primary field of his research addressed under Biochemistry.
His Pathology study integrates concerns from other disciplines, such as Psoriasis, Serpin, Cell membrane and Epidermis. The JAK-STAT signaling pathway research Paul F. Goetinck does as part of his general Tyrosine kinase study is frequently linked to other disciplines of science, such as Epidermal cell differentiation, therefore creating a link between diverse domains of science. The study incorporates disciplines such as Angiogenesis, Wound healing, Granulation tissue, Integrin and Receptor tyrosine kinase in addition to Fibronectin.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Delayed wound repair and impaired angiogenesis in mice lacking syndecan-4
Frank Echtermeyer;Michael Streit;Sarah Wilcox-Adelman;Stefania Saoncella.
Journal of Clinical Investigation (2001)
Syndecan-4 signals cooperatively with integrins in a Rho-dependent manner in the assembly of focal adhesions and actin stress fibers.
Stefania Saoncella;Frank Echtermeyer;Fabienne Denhez;Julie K. Nowlen.
Proceedings of the National Academy of Sciences of the United States of America (1999)
Essential and separable roles for Syndecan-3 and Syndecan-4 in skeletal muscle development and regeneration.
D.D.W. Cornelison;Sarah A. Wilcox-Adelman;Paul F. Goetinck;Heikki Rauvala.
Genes & Development (2004)
Phosphoinositide 3-kinase signaling to Akt promotes keratinocyte differentiation versus death.
Enzo Calautti;Jian Li;Stefania Saoncella;Janice L. Brissette.
Journal of Biological Chemistry (2005)
The tandemly repeated sequences of cartilage link protein contain the sites for interaction with hyaluronic acid.
P F Goetinck;N S Stirpe;P A Tsonis;D Carlone.
Journal of Cell Biology (1987)
Matrix Contraction by Dermal Fibroblasts Requires Transforming Growth Factor-β/Activin-Linked Kinase 5, Heparan Sulfate-Containing Proteoglycans, and MEK/ERK: Insights into Pathological Scarring in Chronic Fibrotic Disease
Yunliang Chen;Xu Shi-wen;Jonathan van Beek;Laura Kennedy.
American Journal of Pathology (2005)
Protein kinase C regulates the recruitment of syndecan-4 into focal contacts.
P C Baciu;P F Goetinck.
Molecular Biology of the Cell (1995)
Syndecan-4 modulates focal adhesion kinase phosphorylation
Sarah A. Wilcox-Adelman;Fabienne Denhez;Paul F. Goetinck.
Journal of Biological Chemistry (2002)
Inhibition of pulmonary fibrosis in mice by CXCL10 requires glycosaminoglycan binding and syndecan-4
Dianhua Jiang;Jiurong Liang;Gabriele S. Campanella;Rishu Guo.
Journal of Clinical Investigation (2010)
Structure of the gene for cartilage matrix protein, a modular protein of the extracellular matrix. Exon/intron organization, unusual splice sites, and relation to alpha chains of beta 2 integrins, von Willebrand factor, complement factors B and C2, and epidermal growth factor.
I Kiss;F Deák;R G Holloway;H Delius.
Journal of Biological Chemistry (1989)
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