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Biology and Biochemistry

D-Index
55
Citations
9679
World Ranking
15171
National Ranking
472

Overview

Nico Mitro is affiliated with the University of Milan in Italy. Their research primarily intersects the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Within these areas, they have contributed notably to the subfields of Molecular Biology, Physiology, Cancer Research, Cellular and Molecular Neuroscience, and Epidemiology.

Their work covers several focused topics that include:

  • Adipose Tissue and Metabolism
  • Mitochondrial Function and Pathology
  • Adipokines, Inflammation, and Metabolic Diseases
  • Epigenetics and DNA Methylation
  • Cancer, Hypoxia, and Metabolism
  • Metabolomics and Mass Spectrometry Studies
  • Diet and metabolism studies

Nico Mitro has frequently published in specific research venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • International Journal of Molecular Sciences
  • Nature Metabolism
  • Cardiovascular Research
  • Cells

Recent publications include:

  • Ejection of damaged mitochondria and their removal by macrophages ensure efficient thermogenesis in brown adipose tissue, 2022, Cell Metabolism
  • PCSK9 deficiency rewires heart metabolism and drives heart failure with preserved ejection fraction, 2021, European Heart Journal
  • The mitochondrial protein Opa1 promotes adipocyte browning that is dependent on urea cycle metabolites, 2021, Nature Metabolism
  • Ca2+ overload- and ROS-associated mitochondrial dysfunction contributes to δ-tocotrienol-mediated paraptosis in melanoma cells, 2021, APOPTOSIS
  • Regulatory mechanisms of the early phase of white adipocyte differentiation: an overview, 2022, Cellular and Molecular Life Sciences

Collaborations are an important aspect of their research, frequently co-authoring with:

  • Matteo Audano
  • Silvia Pedretti
  • Donatella Caruso
  • Giuseppe Danilo Norata
  • Maurizio Crestani

Best Publications

  • Fatty acid metabolism complements glycolysis in the selective regulatory T cell expansion during tumor growth

    Ilenia Pacella;Claudio Procaccini;Chiara Focaccetti;Stefano Miacci

  • T0901317 is a potent PXR ligand: implications for the biology ascribed to LXR.

    Nico Mitro;Nico Mitro;Leo Vargas;Russell Romeo;Alan Koder

  • Inhibition of Class I Histone Deacetylases Unveils a Mitochondrial Signature and Enhances Oxidative Metabolism in Skeletal Muscle and Adipose Tissue

    Andrea Galmozzi;Nico Mitro;Alessandra Ferrari;Elise Gers

  • The negative effects of bile acids and tumor necrosis factor-alpha on the transcription of cholesterol 7alpha-hydroxylase gene (CYP7A1) converge to hepatic nuclear factor-4: a novel mechanism of feedback regulation of bile acid synthesis mediated by nuclear receptors.

    Emma De Fabiani;Nico Mitro;Ana Cecilia Anzulovich;Alessandra Pinelli

  • Coordinated Control of Cholesterol Catabolism to Bile Acids and of Gluconeogenesis via a Novel Mechanism of Transcription Regulation Linked to the Fasted-to-fed Cycle

    Emma De Fabiani;Nico Mitro;Federica Gilardi;Donatella Caruso

  • The Small Molecule Harmine Is an Antidiabetic Cell-Type-Specific Regulator of PPARγ Expression

    Hironori Waki;Kye Won Park;Nico Mitro;Liming Pei

  • PPAR Agonists and Metabolic Syndrome: An Established Role?

    Margherita Botta;Matteo Audano;Amirhossein Sahebkar;Cesare R Sirtori

  • Extracellular matrix mechanical cues regulate lipid metabolism through Lipin-1 and SREBP.

    Patrizia Romani;Irene Brian;Giulia Santinon;Arianna Pocaterra

  • Study of 1,4-Dihydropyridine Structural Scaffold: Discovery of Novel Sirtuin Activators and Inhibitors

    Antonello Mai;Sergio Valente;Sarah Meade;Vincenzo Carafa

  • Insights into the mechanism of partial agonism: crystal structures of the peroxisome proliferator-activated receptor gamma ligand-binding domain in the complex with two enantiomeric ligands.

    Giorgio Pochetti;Cristina Godio;Nico Mitro;Donatella Caruso

  • Minor components of olive oil modulate proatherogenic adhesion molecules involved in endothelial activation.

    Mario Dell'Agli;Rossana Fagnani;Nico Mitro;Samuele Scurati

  • Short-Term Fasting Reveals Amino Acid Metabolism as a Major Sex-Discriminating Factor in the Liver

    Sara Della Torre;Nico Mitro;Clara Meda;Federica Lolli

  • Levels and actions of progesterone and its metabolites in the nervous system during physiological and pathological conditions.

    Roberto Cosimo Melcangi;Silvia Giatti;Donato Calabrese;Marzia Pesaresi

  • Obesity-Induced Metabolic Stress Leads to Biased Effector Memory CD4+ T Cell Differentiation via PI3K p110δ-Akt-Mediated Signals

    Claudio Mauro;Joanne Smith;Danilo Cucchi;David Coe

  • ELOVL5 mutations cause spinocerebellar ataxia 38.

    Eleonora Di Gregorio;Barbara Borroni;Elisa Giorgio;Daniela Lacerenza

  • Lipids in the nervous system: from biochemistry and molecular biology to patho-physiology.

    Gaia Cermenati;Nico Mitro;Matteo Audano;Roberto C. Melcangi

  • Gene set enrichment in eQTL data identifies novel annotations and pathway regulators.

    Chunlei Wu;David L. Delano;Nico Mitro;Stephen V. Su

  • An Essential Role for Liver ERα in Coupling Hepatic Metabolism to the Reproductive Cycle

    Sara Della Torre;Nico Mitro;Roberta Fontana;Roberta Fontana;Monica Gomaraschi

  • Diabetes-induced myelin abnormalities are associated with an altered lipid pattern: Protective effects of LXR activation

    Gaia Cermenati;Federico Abbiati;Solei Cermenati;Elisabetta Brioschi

  • Myeloid apolipoprotein E controls dendritic cell antigen presentation and T cell activation

    Fabrizia Bonacina;David Coe;Guosu Wang;Maria P. Longhi

Frequent Co-Authors

Donatella Caruso
Donatella Caruso University of Milan
Roberto C. Melcangi
Roberto C. Melcangi University of Milan
Luis M. Garcia-Segura
Luis M. Garcia-Segura Spanish National Research Council
Giuseppe Danilo Norata
Giuseppe Danilo Norata University of Milan
Adriana Maggi
Adriana Maggi University of Milan
Alberico L. Catapano
Alberico L. Catapano University of Milan
Ettore Novellino
Ettore Novellino University of Naples Federico II
Elena Tremoli
Elena Tremoli University of Milan
Antonio Lavecchia
Antonio Lavecchia University of Naples Federico II
Alfredo Brusco
Alfredo Brusco University of Turin

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