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Biology and Biochemistry

D-Index
66
Citations
27950
World Ranking
8452
National Ranking
3804

Overview

N. Leigh Anderson is affiliated with Argonne National Laboratory in the United States and has a research focus primarily in Medicine and Engineering. Their work spans multiple subfields including Infectious Diseases, Biomedical Engineering, Epidemiology, Molecular Biology, and Cardiology and Cardiovascular Medicine.

The scientist's research topics concentrate on areas such as SARS-CoV-2 detection and testing, biosensors and analytical detection methods, respiratory viral infections, and COVID-19 research. Additional subjects include advanced biosensing and bioanalysis techniques, cytomegalovirus and herpesvirus research, and broader viral infections and immunology studies.

Several recent publications authored or co-authored by N. Leigh Anderson include:

  • Cov-MS: A Community-Based Template Assay for Mass-Spectrometry-Based Protein Detection in SARS-CoV-2 Patients, 2021, JACS Au
  • Virome-wide detection of natural infection events and the associated antibody dynamics using longitudinal highly-multiplexed serology, 2023, Nature Communications
  • Acoustic ejection mass spectrometry empowers ultra-fast protein biomarker quantification, 2024, Nature Communications
  • Cov2MS: An Automated and Quantitative Matrix-Independent Assay for Mass Spectrometric Measurement of SARS-CoV-2 Nucleocapsid Protein, 2022, Analytical Chemistry
  • A high throughput immuno-affinity mass spectrometry method for detection and quantitation of SARS-CoV-2 nucleoprotein in human saliva and its comparison with RT-PCR, RT-LAMP, and lateral flow rapid antigen test, 2024, Clinical Chemistry and Laboratory Medicine (CCLM)

Frequent publication venues for Anderson include:

  • Nature Communications
  • bioRxiv (Cold Spring Harbor Laboratory)
  • JACS Au
  • Analytical Chemistry
  • Clinical Chemistry and Laboratory Medicine (CCLM)

Regularly collaborating with other researchers, Anderson's frequent co-authors are:

  • Morteza Razavi (7 co-publications)
  • Richard Yip (5 co-publications)
  • Bart Van Puyvelde (4 co-publications)
  • Geert A. Martens (4 co-publications)
  • Dieter Deforce (4 co-publications)

The scientist's work involves the development and application of mass spectrometry-based methods for the detection and quantitation of viral proteins, especially related to SARS-CoV-2. This includes the advancement of template assays and high-throughput immuno-affinity techniques tailored to improve analytical sensitivity and throughput for viral diagnostics.

Best Publications

  • The Human Plasma Proteome History, Character, and Diagnostic Prospects

    N. Leigh Anderson;Norman G. Anderson

  • Proteome and proteomics: New technologies, new concepts, and new words

    N. Leigh Anderson;Norman G. Anderson

  • Quantitative Mass Spectrometric Multiple Reaction Monitoring Assays for Major Plasma Proteins

    N. Leigh Anderson;Christie L. Hunter

  • An Information-Intensive Approach to the Molecular Pharmacology of Cancer

    John N. Weinstein;Timothy G. Myers;Patrick M. O'Connor;Stephen H. Friend

  • Multi-site assessment of the precision and reproducibility of multiple reaction monitoring–based measurements of proteins in plasma

    Terri A. Addona;Susan E. Abbatiello;Birgit Schilling;Steven J. Skates

  • The Human Plasma Proteome A Nonredundant List Developed by Combination of Four Separate Sources

    N. Leigh Anderson;Malu Polanski;Rembert Pieper;Tina Gatlin

  • Mass spectrometric quantitation of peptides and proteins using Stable Isotope Standards and Capture by Anti-Peptide Antibodies (SISCAPA).

    N. Leigh Anderson;Norman G. Anderson;Lee R. Haines;Darryl B. Hardie

  • The human serum proteome: display of nearly 3700 chromatographically separated protein spots on two-dimensional electrophoresis gels and identification of 325 distinct proteins.

    Rembert Pieper;Christine L. Gatlin;Anthony J. Makusky;Paul S. Russo

  • Multiple Reaction Monitoring-based, Multiplexed, Absolute Quantitation of 45 Proteins in Human Plasma

    Michael A. Kuzyk;Derek Smith;Juncong Yang;Tyra J. Cross

  • The Clinical Plasma Proteome: A Survey of Clinical Assays for Proteins in Plasma and Serum

    N. Leigh Anderson

  • A list of candidate cancer biomarkers for targeted proteomics.

    Malu Polanski;N. Leigh Anderson

  • Multi‐component immunoaffinity subtraction chromatography: An innovative step towards a comprehensive survey of the human plasma proteome

    Rembert Pieper;Qin Su;Christine L. Gatlin;Shih-Ting Huang

  • High-Abundance Polypeptides of the Human Plasma Proteome Comprising the Top 4 Logs of Polypeptide Abundance

    Glen L. Hortin;Denis Sviridov;N. Leigh Anderson

  • Sweetening the Pot: Adding Glycosylation to the Biomarker Discovery Equation

    Penelope M. Drake;Wonryeon Cho;Bensheng Li;Akraporn Prakobphol

  • Precision of heavy-light peptide ratios measured by maldi-tof mass spectrometry.

    N. Leigh Anderson;Morteza Razavi;Terry W. Pearson;Gary Kruppa

  • Analytical techniques for cell fractions

    Karen E. Willard;Carol Smith Giometti;N. Leigh Anderson;Timothy E. O'Connor

  • An updated two‐dimensional gel database of rat liver proteins useful in gene regulation and drug effect studies

    N. Leigh Anderson;Ricardo Esquer-Blasco;Jean-Paul Hofmann;Lydie Meheus

  • Proteomics: applications in basic and applied biology.

    N Leigh Anderson;Alastair D Matheson;Sandra Steiner

  • A Human Proteome Detection and Quantitation Project

    N. Leigh Anderson;Norman G. Anderson;Terry W. Pearson;Christoph H. Borchers

  • Proteomics: from basic research to diagnostic application. A review of requirements & needs.

    Frank Vitzthum;Fritz Behrens;N Leigh Anderson;John H Shaw

Frequent Co-Authors

Steven A. Carr
Steven A. Carr Broad Institute
Amanda G. Paulovich
Amanda G. Paulovich Fred Hutchinson Cancer Research Center
Christoph H. Borchers
Christoph H. Borchers McGill University
Henry Rodriguez
Henry Rodriguez National Institutes of Health
daniel c liebler
daniel c liebler Vanderbilt University
Susan J. Fisher
Susan J. Fisher University of California, San Francisco
Fred E. Regnier
Fred E. Regnier Purdue University West Lafayette
Bradford W. Gibson
Bradford W. Gibson Buck Institute for Research on Aging
Paul Tempst
Paul Tempst Memorial Sloan Kettering Cancer Center
Feng Wang
Feng Wang University of California, Berkeley

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