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Biology and Biochemistry

D-Index
55
Citations
19531
World Ranking
14767
National Ranking
6174

Overview

Michèle M. Sale is affiliated with the University of Virginia in the United States. Their research spans multiple fields within medicine and biochemistry, genetics, and molecular biology, with a particular focus on genetics, molecular biology, epidemiology, cardiology and cardiovascular medicine, and otorhinolaryngology.

The main topics of their work include:

  • Genetic Associations and Epidemiology
  • Ear Surgery and Otitis Media
  • Head and Neck Anomalies
  • Forensic and Genetic Research
  • Race, Genetics, and Society
  • Epigenetics and DNA Methylation
  • Adipose Tissue and Metabolism

Michèle M. Sale's recent scholarly contributions include the following publications:

  • "Genome-Wide Association Study Meta-Analysis of Stroke in 22 000 Individuals of African Descent Identifies Novel Associations With Stroke" (2020) published in Stroke
  • "Meta-analysis of Correlated Traits via Summary Statistics from GWASs with an Application in Hypertension" (2020) published by UNC Libraries
  • "Otitis media susceptibility and shifts in the head and neck microbiome due to SPINK5 variants" (2020) published in Journal of Medical Genetics
  • "Genetic landscape of Gullah African Americans" (2021) published in American Journal of Physical Anthropology
  • "Multi-omic analysis of stroke recurrence in African Americans from the Vitamin Intervention for Stroke Prevention (VISP) clinical trial" (2021) published in PLoS ONE

Their work has appeared frequently in several publication venues including:

  • UNC Libraries
  • PLoS ONE
  • UMYU Journal of Microbiology Research (UJMR)
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Stroke

Frequent collaborators in their research include:

  • Keith L. Keene
  • Bradford B. Worrall
  • Wei-Min Chen
  • Carl D. Langefeld
  • Myriam Fornage

The scientific focus of Michèle M. Sale broadly integrates genetic and epidemiological aspects of diseases, with particular attention to stroke, hypertension, and otitis media. They contribute to understanding the genetic factors underpinning disease susceptibility and progression, especially within populations of African descent. Their research also explores microbiome influences and molecular pathways associated with head and neck conditions.

Best Publications

  • Robust relationship inference in genome-wide association studies

    Ani Manichaikul;Josyf C. Mychaleckyj;Stephen S. Rich;Kathy Daly

  • A genome-wide association search for type 2 diabetes genes in African Americans.

    N D Palmer;C W McDonough;P J Hicks;B H Roh

  • Retinopathy of prematurity: recent advances in our understanding

    C M Wheatley;J L Dickinson;D A Mackey;J E Craig

  • Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies.

    Matthew Traylor;Martin Farrall;Elizabeth G Holliday;Cathie Sudlow

  • Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

    Cristian Pattaro;Alexander Teumer;Mathias Gorski;Audrey Y. Chu

  • Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.

    S Ligthart;A Vaez;U Võsa;M G Stathopoulou

  • Impact of common genetic determinants of Hemoglobin A1c on type 2 diabetes risk and diagnosis in ancestrally diverse populations: A transethnic genome-wide meta-analysis

    Eleanor Wheeler;Aaron Leong;Ching-Ti Liu;Marie-France Hivert

  • Meta-analysis of Correlated Traits via Summary Statistics from GWASs with an Application in Hypertension

    Xiaofeng Zhu;Tao Feng;Tao Feng;Bamidele O. Tayo;Jingjing Liang

  • A meta-analysis identifies new loci associated with body mass index in individuals of African ancestry.

    Keri L. Monda;Keri L. Monda;Gary K. Chen;Kira C. Taylor;Kira C. Taylor;Cameron Palmer;Cameron Palmer

  • Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes

    Rainer Malik;Ganesh Chauhan;Matthew Traylor;Muralidharan Sargurupremraj

  • Linkage of Genetic Markers on Human Chromosomes 20 and 12 to NIDDM in Caucasian Sib Pairs With a History of Diabetic Nephropathy

    Donald W Bowden;Michèle Sale;Timothy D Howard;Asif Qadri

  • Loci associated with ischaemic stroke and its subtypes (SiGN) : A genome-wide association study

    Sara L Pulit;Patrick F McArdle;Quenna Wong;Rainer Malik

  • Genome-wide Association Analysis of Blood-Pressure Traits in African-Ancestry Individuals Reveals Common Associated Genes in African and Non-African Populations

    Nora Franceschini;Ervin Fox;Zhaogong Zhang;Zhaogong Zhang;Todd L. Edwards

  • Meta-Analysis of Genome-Wide Association Studies in African Americans Provides Insights into the Genetic Architecture of Type 2 Diabetes

    Maggie C Y Ng;Daniel Shriner;Brian H Chen;Jiang Li

  • Mutations at the BLK locus linked to maturity onset diabetes of the young and β-cell dysfunction

    Maciej Borowiec;Chong W. Liew;Ryan Thompson;Watip Boonyasrisawat

  • A genome scan for diabetic nephropathy in African Americans.

    Donald W. Bowden;Carla J. Colicigno;Carl D. Langefeld;Michèle M. Sale

  • A genome-wide association study for diabetic nephropathy genes in African Americans

    Caitrin W. McDonough;Nicholette D. Palmer;Pamela J. Hicks;Bong H. Roh

  • Association Analysis in African Americans of European-Derived Type 2 Diabetes Single Nucleotide Polymorphisms From Whole-Genome Association Studies

    Joshua P. Lewis;Nicholette D. Palmer;Pamela J. Hicks;Michele M. Sale

  • Trans-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

    Mahajan A;Spracklen Cn;Zhang W;Ng Mc

  • Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE Collaboration): a meta-analysis of genome-wide association studies | NOVA. The University of Newcastle's Digital Repository

    Matthew Traylor;Martin Farrall;Unnur Thorsteinsdottir;Mike A. Nalls

Frequent Co-Authors

Stephen S. Rich
Stephen S. Rich University of Virginia
Wei-Min Chen
Wei-Min Chen University of Virginia
Donald W. Bowden
Donald W. Bowden Wake Forest University
Carl D. Langefeld
Carl D. Langefeld Wake Forest University
Barry I. Freedman
Barry I. Freedman Wake Forest University
Josyf C. Mychaleckyj
Josyf C. Mychaleckyj University of Virginia
Bruce M. Psaty
Bruce M. Psaty University of Washington
Jerome I. Rotter
Jerome I. Rotter UCLA Medical Center
Jamie E. Craig
Jamie E. Craig Flinders University
David A. Mackey
David A. Mackey University of Western Australia

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