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Biology and Biochemistry
South Africa
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
95
Citations
34336
World Ranking
1897
National Ranking
2

Medicine

D-Index
95
Citations
34241
World Ranking
10046
National Ranking
19

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in South Africa Leader Award
  • 2025 - Research.com Biology and Biochemistry in South Africa Leader Award
  • 2023 - Research.com Biology and Biochemistry in South Africa Leader Award
  • 2022 - Research.com Biology and Biochemistry in South Africa Leader Award

Overview

Michael S. Pepper is affiliated with the University of Pretoria in South Africa. Their research primarily spans the field of Medicine, with a substantial focus on related subfields such as Molecular Biology, Genetics, Pediatrics, Perinatology and Child Health, Physiology, and Infectious Diseases.

Their frequent publication venues include:

  • South African Medical Journal
  • Methods in molecular biology
  • International Journal of Molecular Sciences
  • Frontiers in Immunology
  • Stem Cells International

Recent notable papers authored in collaboration with others cover several topics from immunology to molecular mechanisms in disease. These include:

  • "SARS-CoV-2 Variants, Vaccines, and Host Immunity" (2022) published in Frontiers in Immunology
  • "Adipogenesis: A Complex Interplay of Multiple Molecular Determinants and Pathways" (2020) published in International Journal of Molecular Sciences
  • "A COVID-19 Vaccine: Big Strides Come with Big Challenges" (2021) published in Vaccines
  • "Molecular mechanisms underpinning sarcomas and implications for current and future therapy" (2021) published in Signal Transduction and Targeted Therapy
  • "Lessons Learned from Somatic Cell Nuclear Transfer" (2020) published in International Journal of Molecular Sciences

Michael S. Pepper has collaborated frequently with the following researchers:

  • Melvin Ambele
  • Juanita Mellet
  • Chrisna Durandt
  • Candice Laverne Hendricks
  • Ignatius M. Viljoen

The scientist's main research topics encompass a range of biological and medical areas, including:

  • Mesenchymal stem cell research
  • Neonatal and fetal brain pathology
  • Adipose Tissue and Metabolism
  • Biomedical Ethics and Regulation
  • CRISPR and Genetic Engineering
  • Neonatal Respiratory Health Research
  • Cancer Cells and Metastasis

Best Publications

  • Vascular endothelial growth factor‐C‐mediated lymphangiogenesis promotes tumour metastasis

    Stefano J. Mandriota;Lotta Jussila;Michael Jeltsch;Amelia Compagni

  • Potent synergism between vascular endothelial growth factor and basic fibroblast growth factor in the induction of angiogenesis in vitro

    M.S. Pepper;N. Ferrara;L. Orci;R. Montesano

  • Genistein, a dietary-derived inhibitor of in vitro angiogenesis

    Theodore Fotsis;Michael Pepper;Herman Adlercreutz;Gudrun Fleischmann

  • Role of the Matrix Metalloproteinase and Plasminogen Activator–Plasmin Systems in Angiogenesis

    Michael S. Pepper

  • The endogenous oestrogen metabolite 2-methoxyoestradiol inhibits angiogenesis and suppresses tumour growth

    Theodore Fotsis;Youming Zhang;Michael S. Pepper;Herman Adlercreutz

  • Transforming Growth Factor-beta: Vasculogenesis, Angiogenesis, and Vessel Wall Integrity

    Michael S Pepper

  • Vascular endothelial growth factor (VEGF) induces plasminogen activators and plasminogen activator inhibitor-1 in microvascular endothelial cells

    M.S. Pepper;N. Ferrara;L. Orci;R. Montesano

  • Flavonoids, dietary-derived inhibitors of cell proliferation and in vitro angiogenesis.

    Theodore Fotsis;Michael S. Pepper;Erkan Aktas;Stephen Breit

  • Vascular endothelial growth factor B (VEGF-B) binds to VEGF receptor-1 and regulates plasminogen activator activity in endothelial cells.

    Birgitta Olofsson;Eija Korpelainen;Michael S. Pepper;Stefano J. Mandriota

  • Adipocyte and adipogenesis

    Aus Tariq Ali;Warren E. Hochfeld;Renier Myburgh;Michael S. Pepper;Michael S. Pepper

  • The role of reactive oxygen species in mesenchymal stem cell adipogenic and osteogenic differentiation: a review.

    Fatemeh Atashi;Ali Modarressi;Michael Sean Pepper

  • Transforming growth factor-beta 1 modulates basic fibroblast growth factor-induced proteolytic and angiogenic properties of endothelial cells in vitro.

    Michael Sean Pepper;Dominique Belin;Roberto Montesano;Lelio Orci

  • Molecular characterization of lymphatic endothelial cells

    Simona Podgrabinska;Pascal Braun;Paula Velasco;Bryan Kloos

  • Increased proteolytic activity is responsible for the aberrant morphogenetic behavior of endothelial cells expressing the middle T oncogene.

    R. Montesano;M.S. Pepper;U. Möhle-Steinlein;W. Risau

  • Lymphangiogenesis and Tumor Metastasis: Myth or Reality?

    Michael S. Pepper

  • Genistein, a dietary ingested isoflavonoid, inhibits cell proliferation and in vitro angiogenesis.

    Theodore Fotsis;Michael Pepper;Herman Adlercreutz;Tapio Hase

  • Regulation of angiopoietin-2 mRNA levels in bovine microvascular endothelial cells by cytokines and hypoxia.

    Stefano J. Mandriota;Michael S. Pepper

  • Biphasic effect of transforming growth factor-beta 1 on in vitro angiogenesis.

    Michael Sean Pepper;Jean-Dominique Vassalli;Lelio Orci;Roberto Montesano

  • Manipulating angiogenesis. From basic science to the bedside.

    Michael S. Pepper

  • The Role of Tumor Microenvironment in Chemoresistance: To Survive, Keep Your Enemies Closer

    Dimakatso Alice Senthebane;Arielle Rowe;Nicholas Ekow Thomford;Hendrina Shipanga

Frequent Co-Authors

Roberto Montesano
Roberto Montesano University of Geneva
Lelio Orci
Lelio Orci University of Geneva
Michèle Ramsay
Michèle Ramsay University of the Witwatersrand
Napoleone Ferrara
Napoleone Ferrara University of California, San Diego
Paolo Meda
Paolo Meda University of Geneva
Theodore Fotsis
Theodore Fotsis Foundation for Research and Technology Hellas
Kari Alitalo
Kari Alitalo University of Helsinki
Herman Adlercreutz
Herman Adlercreutz University of Helsinki
Jean-Dominique Vassalli
Jean-Dominique Vassalli University of Geneva
Giulio Gabbiani
Giulio Gabbiani University of Geneva

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