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Biology and Biochemistry

D-Index
55
Citations
16930
World Ranking
14795
National Ranking
35

Overview

Theodore Fotsis is affiliated with the Foundation for Research and Technology Hellas in Greece and conducts research in the fields of Biochemistry, Genetics and Molecular Biology, as well as Engineering. Their work spans multiple subfields including Molecular Biology, Biomedical Engineering, Cell Biology, Surgery, and Cellular and Molecular Neuroscience.

Their research topics cover diverse aspects of biomedical science, focusing notably on:

  • 3D Printing in Biomedical Research
  • Pluripotent Stem Cells Research
  • Tissue Engineering and Regenerative Medicine
  • Cellular Mechanics and Interactions
  • Renal and related cancers
  • Angiogenesis and VEGF in Cancer
  • Electrospun Nanofibers in Biomedical Applications

Frequent coauthors contributing to several joint publications with Theodore Fotsis include Carol Murphy, Eleni Bagli, Μαρία Μάρκου, Angelos Papadopoulos, and Varvara Chalmantzi.

Their research has appeared in multiple scientific journals, with publications in the following venues:

  • Frontiers in Bioengineering and Biotechnology
  • Biomedical Optics Express
  • Stem Cell Research
  • Royal Society Open Science
  • Journal of Cell Science

Selected recent papers authored or coauthored by Theodore Fotsis illustrate their engagement with stem cell biology, tissue engineering, and cellular mechanisms:

  • "Tissue Engineering Using Vascular Organoids From Human Pluripotent Stem Cell Derived Mural Cell Phenotypes" (2020) published in Frontiers in Bioengineering and Biotechnology
  • "Three-dimensional characterization of collagen remodeling in cell-seeded collagen scaffolds via polarization second harmonic generation" (2020) published in Biomedical Optics Express
  • "Embryonic stem cells are devoid of macropinocytosis, a trafficking pathway for activin A in differentiated cells" (2021) published in Journal of Cell Science
  • "Combined transcriptomic and phosphoproteomic analysis of BMP4 signaling in human embryonic stem cells" (2020) published in Stem Cell Research
  • "Translational control in neurovascular brain development" (2021) published in Royal Society Open Science

Best Publications

  • Femtomole sequencing of proteins from polyacrylamide gels by nano-electrospray mass spectrometry

    Matthias Wilm;Andrej Shevchenko;Tony Houthaeve;Stephen Breit

  • Genistein, a dietary-derived inhibitor of in vitro angiogenesis

    Theodore Fotsis;Michael Pepper;Herman Adlercreutz;Gudrun Fleischmann

  • The endogenous oestrogen metabolite 2-methoxyoestradiol inhibits angiogenesis and suppresses tumour growth

    Theodore Fotsis;Youming Zhang;Michael S. Pepper;Herman Adlercreutz

  • Urinary excretion of lignans and isoflavonoid phytoestrogens in japanese men and women consuming a traditional Japanese diet

    H Adlercreutz;H Honjo;A Higashi;T Fotsis

  • Flavonoids, dietary-derived inhibitors of cell proliferation and in vitro angiogenesis.

    Theodore Fotsis;Michael S. Pepper;Erkan Aktas;Stephen Breit

  • Effect of dietary components, including lignans and phytoestrogens, on enterohepatic circulation and liver metabolism of estrogens and on sex hormone binding globulin (SHBG).

    H. Adlercreutz;K. Höckerstedt;C. Bannwart;S. Bloigu

  • Determination of urinary lignans and phytoestrogen metabolites, potential antiestrogens and anticarcinogens, in urine of women on various habitual diets

    H. Adlercreutz;T. Fotsis;C. Bannwart;K. Wähälä

  • Genistein, a dietary ingested isoflavonoid, inhibits cell proliferation and in vitro angiogenesis.

    Theodore Fotsis;Michael Pepper;Herman Adlercreutz;Tapio Hase

  • Excretion of the lignans enterolactone and enterodiol and of equol in omnivorous and vegetarian postmenopausal women and in women with breast cancer

    H. Adlercreutz;H. Adlercreutz;R. Heikkinen;R. Heikkinen;M. Woods;M. Woods;T. Fotsis;T. Fotsis

  • Isotope dilution gas chromatographic-mass spectrometric method for the determination of isoflavonoids, coumestrol, and lignans in food samples.

    Witold Mazur;Theodore Fotsis;Kristina Wähälä;Sirpa Ojala

  • Luteolin Inhibits an Endotoxin-Stimulated Phosphorylation Cascade and Proinflammatory Cytokine Production in Macrophages

    Angeliki Xagorari;Andreas Papapetropoulos;Antonis Mauromatis;Michalis Economou

  • Quantitative determination of lignans and isoflavonoids in plasma of omnivorous and vegetarian women by isotope dilution gas chromatography-mass spectrometry

    H. Adlercreutz;T. Fotsis;J. Lampe;K. Wähälä

  • Lignan and isoflavonoid conjugates in human urine.

    Herman Adlercreutz;Jolande van der Wildt;Judith Kinzel;Hesham Attalla

  • Luteolin Inhibits Vascular Endothelial Growth Factor-Induced Angiogenesis; Inhibition of Endothelial Cell Survival and Proliferation by Targeting Phosphatidylinositol 3′-Kinase Activity

    Eleni Bagli;Maria Stefaniotou;Lucia Morbidelli;Marina Ziche

  • Isotope dilution gas chromatographic-mass spectrometric method for the determination of lignans and isoflavonoids in human urine, including identification of genistein

    Herman Adlercreutz;Theodore Fotsis;Christoph Bannwart;Kristiina Wähälä

  • Inhibition of angiogenesis, tumour growth and metastasis by the NO-releasing vasodilators, isosorbide mononitrate and dinitrate.

    Eva Pipili-Synetos;A. Papageorgiou;Eleni Sakkoula;Georgia Sotiropoulou;Georgia Sotiropoulou

  • Luteolin reduces lipopolysaccharide-induced lethal toxicity and expression of proinflammatory molecules in mice.

    Anastasia Kotanidou;Angeliki Xagorari;Angeliki Xagorari;Eleni Bagli;Eleni Bagli;Panagiota Kitsanta;Panagiota Kitsanta

  • The multicomponent analysis of estrogens in urine by ion exchange chromatography and GC-MS--I. Quantitation of estrogens after initial hydrolysis of conjugates.

    T. Fotsis;H. Adlercreutz

  • VEGF Signals through ATF6 and PERK to Promote Endothelial Cell Survival and Angiogenesis in the Absence of ER Stress

    Evdoxia Karali;Sofia Bellou;Dimitris Stellas;Apostolos Klinakis

  • Early Endosomal Regulation of Smad-dependent Signaling in Endothelial Cells

    Ekaterini Panopoulou;David J. Gillooly;Jeffrey L. Wrana;Marino Zerial

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