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Neuroscience

D-Index
50
Citations
11145
World Ranking
5681
National Ranking
2511

Overview

Mark D. Underwood is affiliated with Columbia University in the United States. Their research spans multiple fields, with a primary focus on Neuroscience and Medicine. Within these broad areas, Underwood's work frequently addresses subfields including Biological Psychiatry, Neurology, Behavioral Neuroscience, Physiology, and Developmental Neuroscience.

Their studies cover a range of topics, notably:

  • Tryptophan and brain disorders
  • Stress Responses and Cortisol
  • Long-Term Effects of COVID-19
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Mitochondrial Function and Pathology
  • Neuroscience of respiration and sleep
  • Diet and metabolism studies

Underwood's publication record includes recent papers such as:

  • COVID-19 induces CNS cytokine expression and loss of hippocampal neurogenesis, 2022, Brain
  • Lipocalin-2 is an anorexigenic signal in primates, 2020, eLife
  • A human brain map of mitochondrial respiratory capacity and diversity, 2025, Nature
  • COVID-19 Induces CNS Cytokine Expression and Loss of Hippocampal Neurogenesis, 2022, SSRN Electronic Journal
  • Integrative transcriptome- and DNA methylation analysis of brain tissue from the temporal pole in suicide decedents and their controls, 2023, Molecular Psychiatry

The venues where Underwood frequently publishes include:

  • Biological Psychiatry
  • Nature
  • The International Journal of Neuropsychopharmacology
  • Brain
  • eLife

Collaboration is evident in their work, with frequent co-authors being:

  • J. John Mann
  • Andrew J. Dwork
  • Mihran J. Bakalian
  • Gorazd Rosoklija
  • Victoria Arango

Best Publications

  • Antidepressants increase neural progenitor cells in the human hippocampus

    Maura Boldrini;Maura Boldrini;Mark D Underwood;René Hen;Gorazd B Rosoklija;Gorazd B Rosoklija

  • A serotonin transporter gene promoter polymorphism (5-HTTLPR) and prefrontal cortical binding in major depression and suicide.

    J. John Mann;Yung Yu Huang;Mark D. Underwood;Suham A. Kassir

  • Localized alterations in pre- and postsynaptic serotonin binding sites in the ventrolateral prefrontal cortex of suicide victims

    Victoria Arango;Mark D. Underwood;Ananda V. Gubbi;J. John Mann

  • Cortical 5-HT2A Receptor Signaling Modulates Anxiety-Like Behaviors in Mice

    Noelia V. Weisstaub;Mingming Zhou;Alena Lira;Evelyn Lambe;Evelyn Lambe

  • Serotonin 1A receptors, serotonin transporter binding and serotonin transporter mRNA expression in the brainstem of depressed suicide victims.

    Victoria Arango;Victoria Arango;Mark D Underwood;Mark D Underwood;Maura Boldrini;Maura Boldrini;Hadassah Tamir;Hadassah Tamir

  • Altered depression-related behaviors and functional changes in the dorsal raphe nucleus of serotonin transporter-deficient mice.

    Alena Lira;Mingming Zhou;Nathalie Castanon;Mark S Ansorge

  • Hippocampal Angiogenesis and Progenitor Cell Proliferation Are Increased with Antidepressant Use in Major Depression

    Maura Boldrini;Maura Boldrini;René Hen;Mark D. Underwood;Gorazd B. Rosoklija;Gorazd B. Rosoklija

  • Serotonin brain circuits involved in major depression and suicide

    Victoria Arango;Mark D Underwood;J John Mann

  • Genetics of the serotonergic system in suicidal behavior.

    Victoria Arango;Yung-yu Huang;Mark D. Underwood;J.John Mann

  • Autonomic and somatomotor effects of amygdala central N. stimulation in awake rabbits

    Craig D. Applegate;Bruce S. Kapp;Mark D. Underwood;Carol L. McNall

  • Molecular aging in human prefrontal cortex is selective and continuous throughout adult life.

    Loubna Erraji-Benchekroun;Loubna Erraji-Benchekroun;Mark D. Underwood;Mark D. Underwood;Victoria Arango;Victoria Arango;Hanga Galfalvy;Hanga Galfalvy

  • Neuronal tryptophan hydroxylase mRNA expression in the human dorsal and median raphe nuclei: major depression and suicide.

    Helene Bach-Mizrachi;Helene Bach-Mizrachi;Mark D Underwood;Mark D Underwood;Suham A Kassir;Mihran J Bakalian

  • Cardiovascular responses elicited by electrical stimulation of the amygdala central nucleus in the rabbit

    Bruce S. Kapp;Michela Gallagher;Mark D. Underwood;Carole L. McNall

  • Serotonin-1A autoreceptor binding in the dorsal raphe nucleus of depressed suicides

    Maura Boldrini;Mark D. Underwood;J. John Mann;Victoria Arango

  • The Neurobiology of Suicide Risk: A Review for the Clinician

    J. John Mann;Maria Oquendo;Mark D. Underwood;Victoria Arango

  • More tryptophan hydroxylase in the brainstem dorsal raphe nucleus in depressed suicides.

    Maura Boldrini;Mark D. Underwood;J. John Mann;Victoria Arango

  • COVID-19 induces CNS cytokine expression and loss of hippocampal neurogenesis

    Unknown

  • Elevated expression of tryptophan hydroxylase-2 mRNA at the neuronal level in the dorsal and median raphe nuclei of depressed suicides.

    Helene Bach-Mizrachi;Mark D. Underwood;Adrienne Tin;S. P. Ellis

  • Fewer pigmented locus coeruleus neurons in suicide victims: Preliminary results

    Victoria Arango;Mark D. Underwood;J. John Mann

  • Association of BDNF Val66Met Polymorphism and Brain BDNF Levels with Major Depression and Suicide.

    Mariam M Youssef;Mark D Underwood;Yung-Yu Huang;Shu-chi Hsiung

  • Research report Localized alterations in pre- and postsynaptic serotonin binding sites in the ventrolateral prefrontal cortex of suicide victims

    Victoria Arango;Mark D. Underwood;Ananda V. Gubbi;John Mann

Frequent Co-Authors

J. John Mann
J. John Mann Columbia University
Gorazd Rosoklija
Gorazd Rosoklija Columbia University
Sarah H. Lisanby
Sarah H. Lisanby Arizona State University
Etienne Sibille
Etienne Sibille University of Toronto
Ramin V. Parsey
Ramin V. Parsey Stony Brook University
René Hen
René Hen Columbia University
Maria A. Oquendo
Maria A. Oquendo University of Pennsylvania
Jay A. Gingrich
Jay A. Gingrich Columbia University
Evelyn K. Lambe
Evelyn K. Lambe University of Toronto
Myron A. Hofer
Myron A. Hofer Columbia University

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