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Chemistry

D-Index
41
Citations
6856
World Ranking
17732
National Ranking
4329

Overview

Kent S. Gates is affiliated with the University of Missouri in the United States and has contributed extensively to the field of biochemistry, genetics, and molecular biology. Their research focuses predominantly on molecular biology, with significant work also conducted in organic chemistry, materials chemistry, infectious diseases, and inorganic chemistry.

The scientist's research topics include:

  • DNA and Nucleic Acid Chemistry
  • DNA Repair Mechanisms
  • HIV/AIDS drug development and treatment
  • RNA Interference and Gene Delivery
  • Enzyme Structure and Function
  • Advanced biosensing and bioanalysis techniques
  • Biochemical and Molecular Research

Frequent publication venues for Kent S. Gates include:

  • Chemical Research in Toxicology
  • ACS Chemical Biology
  • Journal of the American Chemical Society
  • Biochemistry
  • DNA repair

Some notable recent papers are:

  • "Unexpected Complexity in the Products Arising from NaOH-, Heat-, Amine-, and Glycosylase-Induced Strand Cleavage at an Abasic Site in DNA" (2022), Chemical Research in Toxicology
  • "Formation and Repair of an Interstrand DNA Cross-Link Arising from a Common Endogenous Lesion" (2021), Journal of the American Chemical Society
  • "Formation and repair of unavoidable, endogenous interstrand cross-links in cellular DNA" (2020), DNA repair
  • "Inhibition, crystal structures, and in-solution oligomeric structure of aldehyde dehydrogenase 9A1" (2020), Archives of Biochemistry and Biophysics
  • "Reconsidering the Chemical Nature of Strand Breaks Derived from Abasic Sites in Cellular DNA: Evidence for 3'-Glutathionylation" (2022), Journal of the American Chemical Society

Kent S. Gates frequently collaborates with several coauthors, including:

  • Tanhaul Islam
  • Zhiyu Yang
  • Tuhin Haldar
  • Kurt Housh
  • Jay S. Jha

Best Publications

  • An Overview of Chemical Processes That Damage Cellular DNA: Spontaneous Hydrolysis, Alkylation, and Reactions with Radicals

    Kent S. Gates

  • Biologically relevant chemical reactions of N7-alkylguanine residues in DNA.

    Kent S Gates;Tony Nooner;Sanjay Dutta

  • Correction: Corrigendum: Single Molecule Investigation of Ag + Interactions with Single Cytosine-, Methylcytosine- and Hydroxymethylcytosine-Cytosine Mismatches in a Nanopore

    Yong Wang;Bin-Quan Luan;Zhiyu Yang;Xinyue Zhang

  • DNA damage by fasicularin

    Sanjay Dutta;Hideki Abe;Sakae Aoyagi;Chihiro Kibayashi

  • Redox regulation of protein tyrosine phosphatases: structural and chemical aspects.

    John J. Tanner;Zachary D. Parsons;Andrea H. Cummings;Haiying Zhou

  • DNA CLEAVAGE BY THE ANTITUMOR AGENT 3-AMINO-1,2,4-BENZOTRIAZINE 1,4-DIOXIDE (SR4233) : EVIDENCE FOR INVOLVEMENT OF HYDROXYL RADICAL

    J. Scott Daniels;Kent S. Gates

  • Redox-activated, hypoxia-selective DNA cleavage by quinoxaline 1,4-di-N-oxide

    Brian Ganley;Goutam Chowdhury;Jennifer Bhansali;J.Scott Daniels

  • Interstrand Cross-Links Generated by Abasic Sites in Duplex DNA

    Sanjay Dutta;Goutam Chowdhury;Kent S. Gates

  • Interstrand DNA-DNA cross-link formation between adenine residues and abasic sites in duplex DNA.

    Nathan E Price;Kevin M Johnson;Jin Wang;Mostafa I Fekry

  • Oxidative DNA Cleavage by the Antitumor Antibiotic Leinamycin and Simple 1,2-Dithiolan-3-one 1-Oxides: Evidence for Thiol-Dependent Conversion of Molecular Oxygen to DNA-Cleaving Oxygen Radicals Mediated by Polysulfides

    Kaushik Mitra;Woongki Kim;and J. Scott Daniels;Kent S. Gates

  • A Chemical Model for Redox Regulation of Protein Tyrosine Phosphatase 1B (PTP1B) Activity

    Santhosh Sivaramakrishnan;Kripa Keerthi;Kent S. Gates

  • Kinetics and Mechanism of Protein Tyrosine Phosphatase 1B Inactivation by Acrolein

    Derrick R. Seiner;Jason N. LaButti;Kent S. Gates

  • DNA base damage by the antitumor agent 3-amino-1,2,4-benzotriazine 1,4-dioxide (tirapazamine).

    Mustafa Birincioglu;Pawel Jaruga;Goutam Chowdhury;Henry Rodriguez

  • Mechanisms of DNA damage by leinamycin.

    Kent S. Gates

  • 1,2-Dithiolan-3-one 1-Oxides: A Class of Thiol-Activated DNA-Cleaving Agents That Are Structurally Related to the Natural Product Leinamycin†

    Saeid J. Behroozi;Woongki Kim;Jeffrey Dannaldson;Kent S. Gates

  • Generation of reactive oxygen species by a persulfide (BnSSH)

    Tonika Chatterji;Kripa Keerthi;Kent S. Gates

  • Direct Evidence for Bimodal DNA Damage Induced by Tirapazamine

    J S Daniels;K S Gates;C Tronche;M M Greenberg

  • On the Formation and Properties of Interstrand DNA-DNA Cross-links Forged by Reaction of an Abasic Site With the Opposing Guanine Residue of 5′-CAp Sequences in Duplex DNA

    Kevin M. Johnson;Nathan E. Price;Jin Wang;Mostafa I. Fekry

  • 3-Amino-1,2,4-benzotriazine 4-Oxide: Characterization of a New Metabolite Arising from Bioreductive Processing of the Antitumor Agent 3-Amino-1,2,4-benzotriazine 1,4-Dioxide (Tirapazamine)

    Tarra Fuchs;Goutam Chowdhury;Charles L. Barnes;Kent S. Gates

  • Reaction of n-Propanethiol with 3H-1,2-Benzodithiol-3-one 1-Oxide and 5,5-Dimethyl-1,2-dithiolan-3-one 1-Oxide: Studies Related to the Reaction of Antitumor Antibiotic Leinamycin with DNA

    Saeid J. Behroozi;Woongki Kim;Kent S. Gates

  • DNA binding and alkylation by the "left half" of azinomycin B.

    Hong Zang;Kent S. Gates

Frequent Co-Authors

Charles L. Barnes
Charles L. Barnes University of Missouri
Yinsheng Wang
Yinsheng Wang University of California, Riverside
Leonard R. MacGillivray
Leonard R. MacGillivray University of Iowa
Marc M. Greenberg
Marc M. Greenberg Johns Hopkins University
Miral Dizdaroglu
Miral Dizdaroglu National Institute of Standards and Technology
Pawel Jaruga
Pawel Jaruga National Institute of Standards and Technology
Lawrence J. Marnett
Lawrence J. Marnett Vanderbilt University
Jaroslaw W. Zmijewski
Jaroslaw W. Zmijewski University of Alabama at Birmingham
Susan S. Wallace
Susan S. Wallace University of Vermont

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