Her primary scientific interests are in RNA, Virology, Poliovirus, Cell biology and Genetics. Her RNA silencing and RNA-dependent RNA polymerase investigations are all subjects of RNA research. Her Virology study integrates concerns from other disciplines, such as RNA interference and Small interfering RNA.
Her Poliovirus research incorporates themes from Molecular biology and Viral replication. The concepts of her Cell biology study are interwoven with issues in Bacterial Physiological Phenomena, Virus Physiological Phenomena and Microorganism. Her study in Virus is interdisciplinary in nature, drawing from both Mutation, Resistance mutation and Polymerase.
Karla Kirkegaard mainly focuses on RNA, Virology, Molecular biology, Cell biology and Polymerase. The various areas that Karla Kirkegaard examines in her RNA study include Virus, Poliovirus and Viral replication. Her Virology research is multidisciplinary, incorporating perspectives in Replicon and RNA virus.
Her Molecular biology research includes themes of Nucleic acid, Mutant, DNA, Complementary DNA and Transcription. The study incorporates disciplines such as Secretion, Secretory protein and Viral protein in addition to Cell biology. Her Polymerase research is multidisciplinary, incorporating elements of RNA polymerase and Binding site.
Karla Kirkegaard focuses on Dengue virus, Virology, RNA, Virus and Cell biology. Her biological study spans a wide range of topics, including Biological activity, Viral replication and Zika virus. She has included themes like Poliovirus and Gene in her Zika virus study.
Her Virology study combines topics in areas such as Cell, Cytoplasm and Drug resistance. Her work deals with themes such as Golgi apparatus, Endoplasmic reticulum, Viral envelope and Secretion, which intersect with RNA. Her Virus research integrates issues from Viral evolution and Drug.
Karla Kirkegaard mostly deals with Zika virus, Dengue virus, Viral replication, Virology and Cell biology. Her Zika virus study frequently links to other fields, such as RNA. Karla Kirkegaard mostly deals with Viral genome replication in her studies of RNA.
Her Viral replication study integrates concerns from other disciplines, such as Viral envelope, RNA virus and Viral shedding. Her study in Virology focuses on Viral entry in particular. Karla Kirkegaard combines subjects such as Poliovirus and Gene with her study of Cell biology.
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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin.
Subversion of cellular autophagosomal machinery by RNA viruses.
William T Jackson;Thomas H Giddings;Matthew P Taylor;Sara Mulinyawe.
PLOS Biology (2005)
Remodeling the Endoplasmic Reticulum by Poliovirus Infection and by Individual Viral Proteins: an Autophagy-Like Origin for Virus-Induced Vesicles
David A. Suhy;Thomas H. Giddings;Karla Kirkegaard.
Journal of Virology (2000)
The NeST long ncRNA controls microbial susceptibility and epigenetic activation of the interferon-γ locus.
J. Antonio Gomez;Orly L. Wapinski;Yul W. Yang;Jean-François Bureau.
The mechanism of RNA recombination in poliovirus.
Karla Kirkegaard;David Baltimore.
Cellular autophagy: surrender, avoidance and subversion by microorganisms
Karla Kirkegaard;Matthew P. Taylor;William T. Jackson.
Nature Reviews Microbiology (2004)
CELLULAR ORIGIN AND ULTRASTRUCTURE OF MEMBRANES INDUCED DURING POLIOVIRUS INFECTION
A Schlegel;T H Giddings;M S Ladinsky;K Kirkegaard.
Journal of Virology (1996)
A single mutation in poliovirus RNA-dependent RNA polymerase confers resistance to mutagenic nucleotide analogs via increased fidelity
Julie K. Pfeiffer;Karla Kirkegaard.
Proceedings of the National Academy of Sciences of the United States of America (2003)
Increased fidelity reduces poliovirus fitness and virulence under selective pressure in mice.
Julie K. Pfeiffer;Karla Kirkegaard.
PLOS Pathogens (2005)
Inhibition of cellular protein secretion by poliovirus proteins 2B and 3A.
J R Doedens;K Kirkegaard.
The EMBO Journal (1995)
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