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Biology and Biochemistry

D-Index
65
Citations
25349
World Ranking
8952
National Ranking
3975

Overview

Karla Kirkegaard is a researcher affiliated with Stanford University in the United States. Their academic work spans multiple domains within Medicine, with a particular focus on infectious diseases and molecular biology.

The main fields of study for this scientist include Medicine, with specialization areas in Cardiology and Cardiovascular Medicine, Public Health, Environmental and Occupational Health, Molecular Biology, Infectious Diseases, and Epidemiology. The topics addressed in their research encompass Viral Infections and Immunology Research, Viral Gastroenteritis Research and Epidemiology, Whipple's Disease and Interleukins, Mosquito-borne Diseases and Control, HIV Research and Treatment, Respiratory Viral Infections Research, and Bacteriophages and Microbial Interactions.

The recent scholarly output of Karla Kirkegaard includes the following publications:

  • Population-scale tissue transcriptomics maps long non-coding RNAs to complex disease, 2021, Cell
  • Modified cyclodextrins as broad-spectrum antivirals, 2020, Science Advances
  • The Picornaviridae Family: Knowledge Gaps, Animal Models, Countermeasures, and Prototype Pathogens, 2023, The Journal of Infectious Diseases
  • Full-length three-dimensional structure of the influenza A virus M1 protein and its organization into a matrix layer, 2020, PLoS Biology
  • Mechanosensitive extrusion of Enterovirus A71-infected cells from colonic organoids, 2023, Nature Microbiology

Kirkegaard has collaborated frequently with a group of researchers, with whom they have multiple publications. Notable coauthors include David A. Constant, Jasmine Moshiri, Jennifer S Doherty, Valeria Cagno, and Caroline Tapparel.

The preferred venues for publishing include both journals and repositories. Key publication venues are Zenodo (CERN European Organization for Nuclear Research), bioRxiv (Cold Spring Harbor Laboratory), Cell, Science Advances, and The Journal of Infectious Diseases.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Subversion of cellular autophagosomal machinery by RNA viruses.

    William T Jackson;Thomas H Giddings;Matthew P Taylor;Sara Mulinyawe

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Remodeling the Endoplasmic Reticulum by Poliovirus Infection and by Individual Viral Proteins: an Autophagy-Like Origin for Virus-Induced Vesicles

    David A. Suhy;Thomas H. Giddings;Karla Kirkegaard

  • The NeST long ncRNA controls microbial susceptibility and epigenetic activation of the interferon-γ locus.

    J. Antonio Gomez;Orly L. Wapinski;Yul W. Yang;Jean-François Bureau

  • The mechanism of RNA recombination in poliovirus.

    Karla Kirkegaard;David Baltimore

  • Cellular autophagy: surrender, avoidance and subversion by microorganisms

    Karla Kirkegaard;Matthew P. Taylor;William T. Jackson

  • A single mutation in poliovirus RNA-dependent RNA polymerase confers resistance to mutagenic nucleotide analogs via increased fidelity

    Julie K. Pfeiffer;Karla Kirkegaard

  • CELLULAR ORIGIN AND ULTRASTRUCTURE OF MEMBRANES INDUCED DURING POLIOVIRUS INFECTION

    A Schlegel;T H Giddings;M S Ladinsky;K Kirkegaard

  • Increased fidelity reduces poliovirus fitness and virulence under selective pressure in mice.

    Julie K. Pfeiffer;Karla Kirkegaard

  • Inhibition of cellular protein secretion by poliovirus proteins 2B and 3A.

    J R Doedens;K Kirkegaard

  • Neuron-to-neuron transmission of α-synuclein fibrils through axonal transport

    Eric C. Freundt;Nate Maynard;Eileen K. Clancy;Shyamali Roy

  • Covalent bonds between protein and DNA. Formation of phosphotyrosine linkage between certain DNA topoisomerases and DNA.

    Y C Tse;K Kirkegaard;J C Wang

  • Six RNA Viruses and Forty-One Hosts: Viral Small RNAs and Modulation of Small RNA Repertoires in Vertebrate and Invertebrate Systems

    Poornima Parameswaran;Ella Sklan;Courtney Wilkins;Trever Burgon

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Functional Coupling between Replication and Packaging of Poliovirus Replicon RNA

    Constance I. Nugent;Kyle L. Johnson;Peter Sarnow;Peter Sarnow;Karla Kirkegaard;Karla Kirkegaard

  • Coupling between genome translation and replication in an RNA virus.

    Janet E. Novak;Karla Kirkegaard

  • Nonlytic viral spread enhanced by autophagy components

    Sara Whitney Bird;Nathaniel D. Maynard;Markus W. Covert;Karla Kirkegaard

  • Inhibition of endoplasmic reticulum-to-Golgi traffic by poliovirus protein 3A: genetic and ultrastructural analysis.

    J R Doedens;T H Giddings;K Kirkegaard

  • Improved method for detecting poliovirus negative strands used to demonstrate specificity of positive-strand encapsidation and the ratio of positive to negative strands in infected cells.

    J E Novak;K Kirkegaard

Frequent Co-Authors

James C. Wang
James C. Wang Harvard University
Evelina Gatti
Evelina Gatti Aix-Marseille University
Thomas H. Giddings
Thomas H. Giddings University of Colorado Boulder
Shazib Pervaiz
Shazib Pervaiz National University of Singapore
Leonidas C. Platanias
Leonidas C. Platanias Northwestern University
Hsing Jien Kung
Hsing Jien Kung Taipei Medical University
Maurizio Molinari
Maurizio Molinari Universita della Svizzera Italiana
Yee-Joo Tan
Yee-Joo Tan National University of Singapore
Peter Sarnow
Peter Sarnow Stanford University
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center

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