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Biology and Biochemistry

D-Index
53
Citations
8786
World Ranking
16302
National Ranking
567

Overview

Judd M. Aiken is affiliated with the University of Alberta in Canada and has contributed extensively to research in biochemistry, genetics, and molecular biology, with notable involvement in medicine. Their work spans multiple subfields including molecular biology, neurology, physiology, infectious diseases, and nutrition and dietetics.

Their research focuses primarily on topics such as prion diseases and protein misfolding, mitochondrial function and pathology, neurological diseases and metabolism, trace elements in health, metabolism and genetic disorders, genetic neurodegenerative diseases, and adipose tissue and metabolism.

Recent papers by Judd M. Aiken include:

  • Prion protein lowering is a disease-modifying therapy across prion disease stages, strains and endpoints, 2020, Nucleic Acids Research
  • Mitochondrial DNA deletion mutations increase exponentially with age in human skeletal muscle, 2020, Aging Clinical and Experimental Research
  • Chronic wasting disease (CWD) prion strains evolve via adaptive diversification of conformers in hosts expressing prion protein polymorphisms, 2020, Journal of Biological Chemistry
  • Long-Term Incubation PrPCWD with Soils Affects Prion Recovery but Not Infectivity, 2020, Pathogens
  • Chronic wasting disease: a cervid prion infection looming to spillover, 2021, Veterinary Research

Frequent co-authors include:

  • Debbie McKenzie
  • Allen Herbst
  • Jonathan Wanagat
  • Chiye Kim
  • Austin N. Hoang

Judd M. Aiken has published frequently in venues such as bioRxiv (Cold Spring Harbor Laboratory), Pathogens, Journal of Biological Chemistry, GeroScience, and Prion.

Best Publications

  • Mitochondrial DNA–Deletion Mutations Accumulate Intracellularly to Detrimental Levels in Aged Human Skeletal Muscle Fibers

    Entela Bua;Jody Johnson;Allen Herbst;Bridget Delong

  • Mitochondrial DNA deletion mutations colocalize with segmental electron transport system abnormalities, muscle fiber atrophy, fiber splitting, and oxidative damage in sarcopenia

    Jonathan Wanagat;Zhengjin Cao;Pranali Pathare;Judd M. Aiken

  • Prions adhere to soil minerals and remain infectious.

    Christopher J Johnson;Kristen E Phillips;Peter T Schramm;Debbie McKenzie

  • Oral transmissibility of prion disease is enhanced by binding to soil particles.

    Christopher J Johnson;Joel A Pedersen;Rick J Chappell;Debbie McKenzie

  • Mitochondrial abnormalities are more frequent in muscles undergoing sarcopenia

    Entela A. Bua;Susan H. McKiernan;Jonathan Wanagat;Debbie McKenzie

  • Accumulation of mitochondrial DNA deletion mutations in aged muscle fibers: evidence for a causal role in muscle fiber loss.

    Allen Herbst;Jeong W. Pak;Debbie McKenzie;Entela Bua

  • Mitochondrial DNA deletion mutations are concomitant with ragged red regions of individual, aged muscle fibers: analysis by laser-capture microdissection

    Zhengjin Cao;Jonathan Wanagat;Susan H. McKiernan;Judd M. Aiken

  • Caloric restriction reduces fiber loss and mitochondrial abnormalities in aged rat muscle.

    Lauren E. Aspnes;Connie M. Lee;Richard Weindruch;Susan S. Chung

  • Prion protein polymorphisms in white-tailed deer influence susceptibility to chronic wasting disease.

    Chad Johnson;Jody Johnson;Joshua P. Vanderloo;Delwyn Keane

  • Adaptation and Selection of Prion Protein Strain Conformations following Interspecies Transmission of Transmissible Mink Encephalopathy

    Jason C. Bartz;Richard A. Bessen;Debbie McKenzie;Richard F. Marsh

  • The Host Range of Chronic Wasting Disease Is Altered on Passage in Ferrets

    Jason C. Bartz;Richard F. Marsh;Debbie I. McKenzie;Judd M. Aiken

  • Age-Associated Alterations of the Mitochondrial Genome

    Connie M Lee;Richard Weindruch;Judd M Aiken

  • Reversibility of Scrapie Inactivation Is Enhanced by Copper

    Debbie McKenzie;Jason Bartz;Jean Mirwald;Doris Olander

  • Association of age-related mitochondrial abnormalities with skeletal muscle fiber atrophy

    Connie M. Lee;Marisol E. Lopez;Richard Weindruch;Judd M. Aiken

  • High levels of mitochondrial DNA deletions in skeletal muscle of old rhesus monkeys

    Steven R. Schwarze;Connie M. Lee;Susan S. Chung;Ellen B. Roecker

  • Multiple mitochondrial DNA deletions associated with age in skeletal muscle of rhesus monkeys.

    Connie M. Lee;Susan S. Chung;Jean M. Kaczkowski;Richard Weindruch

  • Persistence and expression of Microplitis demolitor polydnavirus in Pseudoplusia includens.

    M. R. Strand;D. I. McKenzie;V. Grassl;B. A. Dover

  • Mitochondrial DNA deletion mutations: a causal role in sarcopenia.

    Debbie McKenzie;Entela Bua;Susan McKiernan;Zhengjin Cao

  • Early-onset calorie restriction conserves fiber number in aging rat skeletal muscle

    Susan H McKiernan;Entela Bua;Jennifer McGorray;Judd Aiken

  • Age-related changes in cardiac structure and function in Fischer 344 × Brown Norway hybrid rats

    Timothy A. Hacker;Susan H. McKiernan;Pamela S. Douglas;Jonathan Wanagat

Frequent Co-Authors

Richard Weindruch
Richard Weindruch University of Wisconsin–Madison
David W. Severson
David W. Severson University of Notre Dame
David Westaway
David Westaway University of Alberta
Gordon H. Dixon
Gordon H. Dixon University of Calgary
Holger Wille
Holger Wille University of Alberta
Lingjun Li
Lingjun Li University of Wisconsin–Madison
Michael R. Strand
Michael R. Strand University of Georgia
Craig H. Benson
Craig H. Benson University of Wisconsin–Madison
David B. Allison
David B. Allison Indiana University
Barry D. Bavister
Barry D. Bavister University of New Orleans

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