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D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
14812
World Ranking
12401
National Ranking
119

Overview

Joseph Lotem is affiliated with the Weizmann Institute of Science in Israel. Their research primarily focuses on Biochemistry, Genetics and Molecular Biology, with additional work in Immunology and Microbiology.

Their subfields of study include Molecular Biology, Immunology, Genetics, and Plant Science. The main topics of their work cover Genomics and Chromatin Dynamics, RNA Research and Splicing, Immune cells in cancer, IL-33, ST2, and ILC Pathways, Inflammatory Bowel Disease, Ubiquitin and proteasome pathways, and Plant Molecular Biology Research.

Recent publications by Joseph Lotem demonstrate contributions to several areas in biology and immunology. These include:

  • Runx3 prevents spontaneous colitis by directing the differentiation of anti-inflammatory mononuclear phagocytes, 2020, PLoS ONE
  • Runx3, Brn3a and Isl1 interplay orchestrates the transcriptional program in the early stages of proprioceptive neuron development, 2024, PLoS Genetics
  • Runx3 and Brn3a interplay orchestrates the transcriptional program in the early stages of proprioceptive neuron development, 2024, Research Square (Research Square)

Their frequent co-authors are:

  • Shay Hantisteanu
  • Ditsa Levanon
  • Yoram Groner
  • Kira Orlovsky
  • Elena Appel

Joseph Lotem's work has appeared in notable venues such as PLoS ONE, PLoS Genetics, and Research Square (Research Square).

Best Publications

  • Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6

    E Yonish-Rouach;D Resnitzky;J Lotem;L Sachs

  • Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs

    Fernando Cruz-Guilloty;Matthew E. Pipkin;Ivana M. Djuretic;Ditsa Levanon

  • Runx3 and Runx1 are required for CD8 T cell development during thymopoiesis.

    Eilon Woolf;Cuiying Xiao;Ofer Fainaru;Joseph Lotem

  • Regulation of normal differentiation in mouse and human myeloid leukemic cells by phorbol esters and the mechanism of tumor promotion.

    Joseph Lotem;Leo Sachs

  • Control of programmed cell death in normal and leukemic cells: new implications for therapy

    L Sachs;J Lotem

  • Hematopoietic Cells From Mice Deficient in Wild-Type p53 Are More Resistant to Induction of Apoptosis by Some Agents

    Joseph Lotem;Leo Sachs

  • Regulation by bcl-2, c-myc, and p53 of susceptibility to induction of apoptosis by heat shock and cancer chemotherapy compounds in differentiation-competent and -defective myeloid leukemic cells.

    Lotem J;Sachs L

  • Regulation of p53 stability and p53-dependent apoptosis by NADH quinone oxidoreductase 1

    Gad Asher;Joseph Lotem;Batya Cohen;Leo Sachs

  • Runx3 regulates mouse TGF‐β‐mediated dendritic cell function and its absence results in airway inflammation

    Ofer Fainaru;Eilon Woolf;Joseph Lotem;Merav Yarmus

  • The RUNX3 gene--sequence, structure and regulated expression.

    Carmen Bangsow;Nir Rubins;Gustavo Glusman;Yael Bernstein

  • Hematopoietic cytokines inhibit apoptosis induced by transforming growth factor beta 1 and cancer chemotherapy compounds in myeloid leukemic cells.

    Joseph Lotem;Leo Sachs

  • Lysosomal destabilization in p53-induced apoptosis

    Xi-Ming Yuan;Wei Li;Helge Dalen;Joseph Lotem

  • The myeloid blood cell differentiation-inducing protein MGI-2A is interleukin-6

    Yosef Shabo;Joseph Lotem;Menachem Rubinstein;Michel Revel

  • Different blocks in the differentiation of myeloid leukemic cells.

    Joseph Lotem;Leo Sachs

  • Rescue from programmed cell death in leukemic and normal myeloid cells

    Joseph Lotem;Edward J. Cragoe;Leo Sachs

  • Spatial and temporal expression pattern of Runx3 (Aml2) and Runx1 (Aml1) indicates non-redundant functions during mouse embryogenesis.

    Ditsa Levanon;Ori Brenner;Varda Negreanu;David Bettoun

  • Cellular oxidative stress and the control of apoptosis by wild-type p53, cytotoxic compounds, and cytokines

    Joseph Lotem;Mira Peled-Kamar;Yoram Groner;Leo Sachs

  • Inhibition of NAD(P)H:quinone oxidoreductase 1 activity and induction of p53 degradation by the natural phenolic compound curcumin

    Peter Tsvetkov;Gad Asher;Veronica Reiss;Yosef Shaul

  • Induction of specific changes in the surface membrane of myeloid leukemic cells by steroid hormones.

    Joseph Lotem;Leo Sachs

  • Thymic abnormalities and enhanced apoptosis of thymocytes and bone marrow cells in transgenic mice overexpressing Cu/Zn-superoxide dismutase: implications for Down syndrome.

    M Peled-Kamar;J Lotem;E Okon;L Sachs

Frequent Co-Authors

Leo Sachs
Leo Sachs Weizmann Institute of Science
Yoram Groner
Yoram Groner Weizmann Institute of Science
Yosef Shaul
Yosef Shaul Weizmann Institute of Science
Amos Tanay
Amos Tanay Weizmann Institute of Science
Gwênlyn Glusman
Gwênlyn Glusman Institute for Systems Biology
Menahem Segal
Menahem Segal Weizmann Institute of Science
Anjana Rao
Anjana Rao La Jolla Institute For Allergy & Immunology
Yosef Shiloh
Yosef Shiloh Tel Aviv University
Doron Lancet
Doron Lancet Weizmann Institute of Science
Gideon Rechavi
Gideon Rechavi Sheba Medical Center

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