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D-Index & Metrics

Neuroscience

D-Index
56
Citations
8802
World Ranking
4600
National Ranking
2077

Overview

Joseph H. Neale is affiliated with Georgetown University in the United States. Their research spans multiple disciplines, primarily focusing on biochemistry, genetics, and molecular biology, with additional work in neuroscience and computer science.

The subfields they have contributed to include biochemistry, cell biology, cellular and molecular neuroscience, computational theory and mathematics, and pharmacology. Their research topics cover a range of areas such as amino acid enzymes and metabolism, biotin and related studies, neuroscience and neuropharmacology research, computational drug discovery methods, pharmacogenetics and drug metabolism, and broader themes within science, research, and medicine.

Joseph H. Neale has published in the Journal of Medicinal Chemistry, with a notable paper titled "How a Medicinal Chemistry Project Changed the Way Prostate Cancer is Diagnosed and Treated," published in 2025.

  • How a Medicinal Chemistry Project Changed the Way Prostate Cancer is Diagnosed and Treated, 2025, Journal of Medicinal Chemistry

Frequent co-authors include Stefano Costanzi and Alan P. Kozikowski, each having collaborated on at least one publication with Neale.

  • Stefano Costanzi
  • Alan P. Kozikowski

The Journal of Medicinal Chemistry represents the primary venue for their work, indicating a focus on the chemistry and molecular design aspects within their research fields.

  • Journal of Medicinal Chemistry

Best Publications

  • Immunohistochemical localization of N-acetylaspartate in rat brain

    John R. Moffett;M. A. Aryan Namboodiri;Charles B. Cangro;Joseph H. Neale

  • N-Acetylaspartylglutamate: the most abundant peptide neurotransmitter in the mammalian central nervous system.

    Joseph H Neale;Tomasz Bzdega;Barbara Wroblewska

  • N‐Acetylaspartylglutamate Selectively Activates mGluR3 Receptors in Transfected Cells

    Barbara Wroblewska;Jarda T. Wroblewski;Sergei Pshenichkin;Alexander Surin

  • Synthesis of Urea-Based Inhibitors as Active Site Probes of Glutamate Carboxypeptidase II: Efficacy as Analgesic Agents

    Alan P. Kozikowski;Jiazhong Zhang;Fajun Nan;Pavel A. Petukhov

  • Design of Remarkably Simple, Yet Potent Urea-Based Inhibitors of Glutamate Carboxypeptidase II (NAALADase)

    Alan P. Kozikowski;Fajun Nan;Paola Conti;Jiazhong Zhang

  • NAAG peptidase inhibitors and their potential for diagnosis and therapy

    Jia Zhou;Joseph H. Neale;Martin G. Pomper;Alan P. Kozikowski

  • High concentrations of N-acetylaspartylglutamate (NAAG) selectively activate NMDA receptors on mouse spinal cord neurons in cell culture

    G. L. Westbrook;M. L. Mayer;M. A. A. Namboodiri;J. H. Neale

  • Opiate peptide modulation of amino acid responses suggests novel form of neuronal communication

    JL Barker;JH Neale;TG Smith;RL Macdonald

  • The neurotransmitter N-acetylaspartylglutamate in models of pain, ALS, diabetic neuropathy, CNS injury and schizophrenia

    Joseph H. Neale;Rafal T. Olszewski;Laura M. Gehl;Barbara Wroblewska

  • N-Acetylation of L-aspartate in the nervous system: differential distribution of a specific enzyme

    M. E. Truckenmiller;M. A. A. Namboodiri;M. J. Brownstein;J. H. Neale

  • Immunohistochemistry and biosynthesis of N-acetylaspartylglutamate in spinal sensory ganglia.

    C. B. Cangro;M. A. A. Namboodiri;L. A. Sklar;A. Corigliano-Murphy

  • N‐Acetylaspartylglutamate Inhibits Forskolin‐Stimulated Cyclic AMP Levels via a Metabotropic Glutamate Receptor in Cultured Cerebellar Granule Cells

    Barbara Wroblewska;Jarda T. Wroblewski;Omar H. Saab;Joseph H. Neale

  • NAAG peptidase inhibition reduces locomotor activity and some stereotypes in the PCP model of schizophrenia via group II mGluR

    Rafal T. Olszewski;Rafal T. Olszewski;Noreen Bukhari;Jia Zhou;Alan P. Kozikowski;Alan P. Kozikowski

  • GABA induces proliferation of immature cerebellar granule cells grown in vitro

    Mónica L. Fiszman;Laura N. Borodinsky;Joseph H. Neale

  • N-Acetylaspartylglutamate activates cyclic AMP-coupled metabotropic glutamate receptors in cerebellar astrocytes

    Barbara Wroblewska;Maria Rita Santi;Joseph H. Neale;Joseph H. Neale

  • Localization of N-acetylaspartylglutamate-like immunoreactivity in selected areas of the rat brain

    Kevin J. Anderson;Daniel T. Monaghan;Charles B. Cangro;M.A.A. Namboodiri

  • 125I-Labelled tetanus toxin as a neuronal marker in tissue cultures derived from embryonic CNS.

    W. Dimpfel;J. H. Neale;E. Habermann

  • Molecular cloning of a peptidase against N-acetylaspartylglutamate from a rat hippocampal cDNA library

    Tomasz Bzdega;Thomas Turi;Barbara Wroblewska;Dewei She

  • Dual Function Glutamate-Related Ligands: Discovery of a Novel, Potent Inhibitor of Glutamate Carboxypeptidase II Possessing mGluR3 Agonist Activity

    Fajun Nan;Tomasz Bzdega;Sergey Pshenichkin;Jarda T. Wroblewski

  • Advances in Understanding the Peptide Neurotransmitter NAAG and Appearance of a New Member of the NAAG Neuropeptide Family

    Joseph H. Neale;Rafal T. Olszewski;Daiying Zuo;Karolina J. Janczura

  • The Regional Distribution of N‐Acetylaspartylglutamate (NAAG) and Peptidase Activity Against NAAG in the Rat Nervous System

    Stefanie Fuhrman;Miklos Palkovits;Martha Cassidy;Joseph H. Neale

  • NAAG peptidase inhibitor increases dialysate NAAG and reduces glutamate, aspartate and GABA levels in the dorsal hippocampus following fluid percussion injury in the rat.

    Chunlong Zhong;Xueren Zhao;Ken C. Van;Tomasz Bzdega

Frequent Co-Authors

Stefano Vicini
Stefano Vicini Georgetown University Medical Center
Bruce G. Lyeth
Bruce G. Lyeth University of California, Davis
Jeffery L. Barker
Jeffery L. Barker National Institutes of Health
Carl W. Cotman
Carl W. Cotman University of California, Irvine
Solomon H. Snyder
Solomon H. Snyder Johns Hopkins University School of Medicine
George R. Uhl
George R. Uhl University of Maryland, Baltimore
Hyun Kim
Hyun Kim Korea University
Jean R. Wrathall
Jean R. Wrathall Georgetown University Medical Center
Gregg E. Homanics
Gregg E. Homanics University of Pittsburgh
Angel L. De Blas
Angel L. De Blas University of Connecticut

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