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Biology and Biochemistry

D-Index
79
Citations
23454
World Ranking
4289
National Ranking
324

Overview

John A. G. Briggs is affiliated with the MRC Laboratory of Molecular Biology in the United Kingdom. Their research spans the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine, with a focus on several subfields including Molecular Biology, Infectious Diseases, Ecology, Virology, and Epidemiology.

The scientist's recent published work includes studies primarily related to viral structure and function. Some of the notable papers are:

  • Structures and distributions of SARS-CoV-2 spike proteins on intact virions, 2020, Nature
  • A thermostable, closed SARS-CoV-2 spike protein trimer, 2020, Nature Structural & Molecular Biology
  • A Bayesian approach to single-particle electron cryo-tomography in RELION-4.0, 2022, eLife
  • Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles, 2020, Science Advances
  • Structural basis for VPS34 kinase activation by Rab1 and Rab5 on membranes, 2021, Nature Communications

Their work covers main topics that include:

  • SARS-CoV-2 and COVID-19 Research
  • Bacteriophages and microbial interactions
  • HIV Research and Treatment
  • Lipid Membrane Structure and Behavior
  • Cellular transport and secretion
  • Advanced Electron Microscopy Techniques and Applications
  • Viral gastroenteritis research and epidemiology

John A. G. Briggs frequently publishes in venues such as bioRxiv (Cold Spring Harbor Laboratory), FEBS Letters, Microscopy and Microanalysis, Science Advances, and Nature Communications.

They maintain ongoing collaborations with several frequent co-authors, including Kun Qu, Xiaoli Xiong, Zunlong Ke, Dustin R. Morado, and Leo C. James.

Best Publications

  • Structures and distributions of SARS-CoV-2 spike proteins on intact virions.

    Zunlong Ke;Joaquin Oton;Kun Qu;Mirko Cortese

  • SARS-CoV-2 evolution during treatment of chronic infection.

    Steven A. Kemp;Dami A. Collier;Dami A. Collier;Rawlings P. Datir;Isabella A. T. M. Ferreira

  • Implementation of a cryo-electron tomography tilt-scheme optimized for high resolution subtomogram averaging.

    Wim J.H. Hagen;William Wan;John A.G. Briggs

  • The stoichiometry of Gag protein in HIV-1

    John A G Briggs;Martha N Simon;Ingolf Gross;Hans-Georg Kräusslich

  • Structural organization of authentic, mature HIV-1 virions and cores.

    John A. G. Briggs;Thomas Wilk;Reinhold Welker;Reinhold Welker;Hans‐Georg Kräusslich

  • The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer

    Elissa D. Pastuzyn;Cameron E. Day;Rachel B. Kearns;Madeleine Kyrke-Smith

  • Nuclear pore scaffold structure analyzed by super-resolution microscopy and particle averaging.

    Anna Szymborska;Alex de Marco;Nathalie Daigle;Volker C. Cordes

  • Correlated fluorescence and 3D electron microscopy with high sensitivity and spatial precision

    Wanda Kukulski;Martin Schorb;Sonja Welsch;Andrea Picco

  • Structure and assembly of immature HIV

    John Briggs;Jamie Riches;Barbel Glass;V. Bartonova

  • An atomic model of HIV-1 capsid-SP1 reveals structures regulating assembly and maturation

    Florian K. M. Schur;Martin Obr;Martin Obr;Wim J. H. Hagen;William Wan

  • Plasma membrane reshaping during endocytosis is revealed by time-resolved electron tomography.

    Wanda Kukulski;Martin Schorb;Marko Kaksonen;John A.G. Briggs

  • Structure of the immature HIV-1 capsid in intact virus particles at 8.8 Å resolution

    Florian K. M. Schur;Wim J. H. Hagen;Michaela Rumlová;Tomáš Ruml

  • A thermostable, closed SARS-CoV-2 spike protein trimer.

    Xiaoli Xiong;Kun Qu;Katarzyna A. Ciazynska;Myra Hosmillo

  • Minimal Tags for Rapid Dual‐Color Live‐Cell Labeling and Super‐Resolution Microscopy

    Ivana Nikić;Tilman Plass;Oliver Schraidt;Jędrzej Szymański

  • Cryo-electron tomographic structure of an immunodeficiency virus envelope complex in situ.

    Giulia Zanetti;John A. G Briggs;Kay Grünewald;Quentin J Sattentau

  • Structural biology in situ--the potential of subtomogram averaging.

    John A. G. Briggs

  • Molecular architecture of the inner ring scaffold of the human nuclear pore complex.

    Jan Kosinski;Shyamal Mosalaganti;Alexander von Appen;Roman Teimer

  • Role of Adaptor Complex AP-3 in Targeting Wild- Type and Mutated CD63 to Lysosomes

    Brian A. Rous;Barbara J. Reaves;Gudrun Ihrke;John A.G. Briggs

  • The Mechanism of HIV-1 Core Assembly: Insights from Three-Dimensional Reconstructions of Authentic Virions

    John A.G. Briggs;Kay Grünewald;Bärbel Glass;Friedrich Förster

  • Virological Synapse-Mediated Spread of Human Immunodeficiency Virus Type-1 between T cells is Sensitive to Entry Inhibition

    Nicola Martin;Sonja Welsch;Clare Jolly;John A. G. Briggs

Frequent Co-Authors

Hans-Georg Kräusslich
Hans-Georg Kräusslich Heidelberg University
Barbara Müller
Barbara Müller University Hospital Heidelberg
Felix T. Wieland
Felix T. Wieland Heidelberg University
Marko Kaksonen
Marko Kaksonen University of Geneva
Larissa Kolesnikova
Larissa Kolesnikova Philipp University of Marburg
Stephan Becker
Stephan Becker Philipp University of Marburg
Ralf Bartenschlager
Ralf Bartenschlager Heidelberg University
Norman E. Davey
Norman E. Davey Institute of Cancer Research
Don C. Lamb
Don C. Lamb Ludwig-Maximilians-Universität München
Takeshi Noda
Takeshi Noda Kyoto University

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