What is he best known for?
The fields of study he is best known for:
His main research concerns Molecular biology, Gene, Genetics, Immunology and Antibody.
The concepts of his Molecular biology study are interwoven with issues in Gene rearrangement, Chromosomal translocation, DNA, Exon and Notch signaling pathway.
His work deals with themes such as Mycosis fungoides and Chromosome 18, which intersect with Gene rearrangement.
When carried out as part of a general Gene research project, his work on Gene expression, Immunoglobulin heavy chain, Nucleic acid sequence and Complementary DNA is frequently linked to work in Classification scheme, therefore connecting diverse disciplines of study.
His study focuses on the intersection of Immunology and fields such as Pathology with connections in the field of T lymphocyte.
Jeffrey Sklar has researched Antibody in several fields, including B-cell lymphoma, Lymphoma and Germline mutation.
His most cited work include:
- TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms (1585 citations)
- Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation (1059 citations)
- Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint-cluster region near a transcriptionally active locus on chromosome 18 (839 citations)
What are the main themes of his work throughout his whole career to date?
Jeffrey Sklar focuses on Molecular biology, Pathology, Gene, Gene rearrangement and Immunology.
The various areas that he examines in his Molecular biology study include Genetics, DNA, Southern blot, Immunoglobulin heavy chain and Chromosomal translocation.
His Genetics research focuses on Cancer research and how it relates to Loss of heterozygosity.
He studied Chromosomal translocation and Follicular lymphoma that intersect with breakpoint cluster region.
He has included themes like Receptor and T lymphocyte in his Pathology study.
His work carried out in the field of Gene rearrangement brings together such families of science as T-Cell Receptor Gene, T-cell receptor, Mycosis fungoides, Flow cytometry and Polymerase chain reaction.
He most often published in these fields:
- Molecular biology (41.40%)
- Pathology (31.21%)
- Gene (21.66%)
What were the highlights of his more recent work (between 2011-2021)?
- MEDLINE (5.10%)
- Precision medicine (5.10%)
- Cancer (10.19%)
In recent papers he was focusing on the following fields of study:
His primary areas of study are MEDLINE, Precision medicine, Cancer, Internal medicine and Oncology.
His research integrates issues of Fatal outcome, Presentation, Ascites, Personalized medicine and Autopsy in his study of MEDLINE.
His Precision medicine study combines topics from a wide range of disciplines, such as Medical physics and Tumor board.
In his study, Refractory cancer, Cancer Histology, Interim analysis and MutL Protein Homolog 1 is strongly linked to Molecular analysis, which falls under the umbrella field of Internal medicine.
As part of one scientific family, Jeffrey Sklar deals mainly with the area of Computational biology, narrowing it down to issues related to the Bioinformatics, and often Cancer research.
His Cancer research study incorporates themes from Chromatin, Histone and Biopsy.
Between 2011 and 2021, his most popular works were:
- Genome-wide detection of DNase I hypersensitive sites in single cells and FFPE tissue samples (222 citations)
- Analytical Validation of the Next-Generation Sequencing Assay for a Nationwide Signal-Finding Clinical Trial: Molecular Analysis for Therapy Choice Clinical Trial (65 citations)
- A Chimeric RNA Characteristic of Rhabdomyosarcoma in Normal Myogenesis Process (43 citations)
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