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D-Index & Metrics

Biology and Biochemistry

D-Index
79
Citations
27889
World Ranking
4242
National Ranking
2076

Overview

Jeffrey Sklar is affiliated with Yale University in the United States. Their research primarily spans the fields of biochemistry, genetics, and molecular biology, with a focus on cancer research and related disciplines.

The main topics addressed in Jeffrey Sklar's work include:

  • Cancer Genomics and Diagnostics
  • Economic and Financial Impacts of Cancer
  • Advances in Oncology and Radiotherapy

Sklar has contributed to notable research published in The Lancet Oncology, a frequent venue for their work. Recent papers include:

  • "Yale Cancer Center Precision Medicine Tumor Board: molecular findings alter a diagnosis and treatment plan" (2021, The Lancet Oncology)
  • "Yale Cancer Center Precision Medicine Tumor Board: new technology, new drugs, and the value of repeat testing" (2020, The Lancet Oncology)

These papers reflect an emphasis on precision medicine approaches within oncology, highlighting molecular diagnostics and the impact of emerging therapies on patient care strategies.

Jeffrey Sklar's collaborative efforts involve several frequent co-authors, including:

  • Karin E. Finberg
  • Zenta Walther
  • Joseph P. Eder
  • Sarah B. Goldberg
  • Joanna Gibson

The co-authors frequently appear alongside Sklar in publications related to cancer research and precision oncology, indicating a research network focused on advancing diagnostic and therapeutic methodologies.

Sklar's work also intersects with subfields such as economics and econometrics, as well as radiology, nuclear medicine, and imaging, demonstrating an interdisciplinary approach to cancer studies. This encompasses analyzing the financial impacts of cancer as well as advancements in radiological techniques relevant to oncology.

Best Publications

  • TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms.

    Leif W. Ellisen;Jeffrey Bird;Daniel C. West;A.Lee Soreng

  • Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation

    Michael L. Cleary;Stephen D. Smith;Jeffrey Sklar

  • Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint-cluster region near a transcriptionally active locus on chromosome 18

    Michael L. Cleary;Jeffrey Sklar

  • Importance of replication in microarray gene expression studies: Statistical methods and evidence from repetitive cDNA hybridizations

    Mei-Ling Ting Lee;Frank C. Kuo;G. A. Whitmore;Jeffrey Sklar

  • Detection of Epstein–Barr Viral Genomes in Reed–Sternberg Cells of Hodgkin's Disease

    Lawrence M. Weiss;Lucile A. Movahed;Roger A. Warnke;Jeffrey Sklar

  • Exclusive development of T cell neoplasms in mice transplanted with bone marrow expressing activated Notch alleles.

    Warren S. Pear;Jon C. Aster;Martin L. Scott;Robert P. Hasserjian

  • Molecular analysis of the t(14;18) chromosomal translocation in malignant lymphomas.

    Lawrence M. Weiss;Roger A. Warnke;Jeffrey Sklar;Michael L. Cleary

  • Epstein-Barr viral DNA in tissues of Hodgkin's disease.

    L. M. Weiss;J. G. Strickler;R. A. Warnke;D. T. Purtilo

  • Immunoglobulin gene rearrangement as a diagnostic criterion of B-cell lymphoma

    Michael L. Cleary;James Chao;Roger Warnke;Jeffrey Sklar

  • Calcium depletion dissociates and activates heterodimeric notch receptors.

    Matthew D. Rand;Lisa M. Grimm;Spyros Artavanis-Tsakonas;Vytas Patriub

  • Detection of Clonal T-Cell Receptor |[gamma]| Gene Rearrangements in Early Mycosis Fungoides/Sezary Syndrome by Polymerase Chain Reaction and Denaturing Gradient Gel Electrophoresis (PCR/DGGE)

    Gary S. Wood;Rosnn M. Tung;Andreas C. Heaffner;Carol F. Crooks

  • Clonal T-cell populations in lymphomatoid papulosis. Evidence of a lymphoproliferative origin for a clinically benign disease.

    Lawrence M. Weiss;Gary S. Wood;Martha Trela;Roger A. Warnke

  • Detection of a second t(14;18) breakpoint cluster region in human follicular lymphomas.

    M L Cleary;N Galili;J Sklar

  • Monoclonality of lymphoproliferative lesions in cardiac-transplant recipients: clonal analysis based on immunoglobulin-gene rearrangements

    Michael L. Cleary;Roger Warnke;Jeffrey Sklar

  • Clonal Rearrangements of T-Cell Receptor Genes in Mycosis Fungoides and Dermatopathic Lymphadenopathy

    Lawrence M. Weiss;Eddie Hu;Gary S. Wood;Courtney Moulds

  • Frequent fusion of the JAZF1 and JJAZ1 genes in endometrial stromal tumors

    Jason I. Koontz;A. Lee Soreng;Marisa Nucci;Frank C. Kuo

  • Detection of mutations by cleavage of DNA heteroduplexes with bacteriophage resolvases.

    Robert D. Mashal;Jason Koontz;Jeffrey Sklar

  • Emergence of idiotype variants during treatment of B-cell lymphoma with anti-idiotype antibodies.

    Timothy Meeker;James Lowder;Michael L. Cleary;Stanford Stewart

  • A neoplastic gene fusion mimics trans-splicing of RNAs in normal human cells.

    Hui Li;Jinglan Wang;Gil Mor;Jeffrey Sklar

  • Importance of replication in microarray gene expression studies: Statistical methods and evidence from repetitive cDNA

    Ting Lee;Frank C. Kuo;G. A. Whitmore;Jeffrey Sklar

Frequent Co-Authors

Michael L. Cleary
Michael L. Cleary Stanford University
Roger A. Warnke
Roger A. Warnke Stanford University
Lawrence M. Weiss
Lawrence M. Weiss City Of Hope National Medical Center
Jon C. Aster
Jon C. Aster Harvard Medical School
Gary S. Wood
Gary S. Wood University of Wisconsin–Madison
Ronald Levy
Ronald Levy Stanford University
Michael P. Link
Michael P. Link Stanford University
Stanley R. Hamilton
Stanley R. Hamilton City Of Hope National Medical Center
A. John Iafrate
A. John Iafrate Harvard University
Richard T. Hoppe
Richard T. Hoppe Stanford University

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