His main research concerns Molecular biology, Gene, Genetics, Immunology and Antibody. The concepts of his Molecular biology study are interwoven with issues in Gene rearrangement, Chromosomal translocation, DNA, Exon and Notch signaling pathway. His work deals with themes such as Mycosis fungoides and Chromosome 18, which intersect with Gene rearrangement.
When carried out as part of a general Gene research project, his work on Gene expression, Immunoglobulin heavy chain, Nucleic acid sequence and Complementary DNA is frequently linked to work in Classification scheme, therefore connecting diverse disciplines of study. His study focuses on the intersection of Immunology and fields such as Pathology with connections in the field of T lymphocyte. Jeffrey Sklar has researched Antibody in several fields, including B-cell lymphoma, Lymphoma and Germline mutation.
Jeffrey Sklar focuses on Molecular biology, Pathology, Gene, Gene rearrangement and Immunology. The various areas that he examines in his Molecular biology study include Genetics, DNA, Southern blot, Immunoglobulin heavy chain and Chromosomal translocation. His Genetics research focuses on Cancer research and how it relates to Loss of heterozygosity.
He studied Chromosomal translocation and Follicular lymphoma that intersect with breakpoint cluster region. He has included themes like Receptor and T lymphocyte in his Pathology study. His work carried out in the field of Gene rearrangement brings together such families of science as T-Cell Receptor Gene, T-cell receptor, Mycosis fungoides, Flow cytometry and Polymerase chain reaction.
His primary areas of study are MEDLINE, Precision medicine, Cancer, Internal medicine and Oncology. His research integrates issues of Fatal outcome, Presentation, Ascites, Personalized medicine and Autopsy in his study of MEDLINE. His Precision medicine study combines topics from a wide range of disciplines, such as Medical physics and Tumor board.
In his study, Refractory cancer, Cancer Histology, Interim analysis and MutL Protein Homolog 1 is strongly linked to Molecular analysis, which falls under the umbrella field of Internal medicine. As part of one scientific family, Jeffrey Sklar deals mainly with the area of Computational biology, narrowing it down to issues related to the Bioinformatics, and often Cancer research. His Cancer research study incorporates themes from Chromatin, Histone and Biopsy.
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TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms
Leif W. Ellisen;Jeffrey Bird;Daniel C. West;A.Lee Soreng.
Cloning and structural analysis of cDNAs for bcl-2 and a hybrid bcl-2/immunoglobulin transcript resulting from the t(14;18) translocation
Michael L. Cleary;Stephen D. Smith;Jeffrey Sklar.
Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint-cluster region near a transcriptionally active locus on chromosome 18
Michael L. Cleary;Jeffrey Sklar.
Proceedings of the National Academy of Sciences of the United States of America (1985)
Importance of replication in microarray gene expression studies: Statistical methods and evidence from repetitive cDNA hybridizations
Mei-Ling Ting Lee;Frank C. Kuo;G. A. Whitmore;Jeffrey Sklar.
Proceedings of the National Academy of Sciences of the United States of America (2000)
Detection of Epstein–Barr Viral Genomes in Reed–Sternberg Cells of Hodgkin's Disease
Lawrence M. Weiss;Lucile A. Movahed;Roger A. Warnke;Jeffrey Sklar.
The New England Journal of Medicine (1989)
Molecular analysis of the t(14;18) chromosomal translocation in malignant lymphomas.
Lawrence M. Weiss;Roger A. Warnke;Jeffrey Sklar;Michael L. Cleary.
The New England Journal of Medicine (1987)
Immunoglobulin gene rearrangement as a diagnostic criterion of B-cell lymphoma
Michael L. Cleary;James Chao;Roger Warnke;Jeffrey Sklar.
Proceedings of the National Academy of Sciences of the United States of America (1984)
Epstein-Barr viral DNA in tissues of Hodgkin's disease.
L. M. Weiss;J. G. Strickler;R. A. Warnke;D. T. Purtilo.
American Journal of Pathology (1987)
Calcium depletion dissociates and activates heterodimeric notch receptors.
Matthew D. Rand;Lisa M. Grimm;Spyros Artavanis-Tsakonas;Vytas Patriub.
Molecular and Cellular Biology (2000)
Detection of Clonal T-Cell Receptor |[gamma]| Gene Rearrangements in Early Mycosis Fungoides/Sezary Syndrome by Polymerase Chain Reaction and Denaturing Gradient Gel Electrophoresis (PCR/DGGE)
Gary S. Wood;Rosnn M. Tung;Andreas C. Heaffner;Carol F. Crooks.
Journal of Investigative Dermatology (1994)
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