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Immunology

D-Index
56
Citations
16362
World Ranking
3675
National Ranking
253

Overview

Hugo O. Besedovsky is affiliated with Philipp University of Marburg in Germany. Their research spans multiple fields, primarily focusing on Medicine, Neuroscience, and Biochemistry, Genetics, and Molecular Biology. In particular, their work covers subfields such as Neurology, Molecular Biology, Infectious Diseases, Immunology, and Developmental Neuroscience.

The scientist's research topics include neuroinflammation and neurodegeneration mechanisms, vagus nerve stimulation research, long-term effects of COVID-19, COVID-19 clinical research studies, receptor mechanisms and signaling, immune response and inflammation, and advanced drug delivery systems.

Recent papers by Besedovsky include:

  • "Intranasal Dexamethasone Reduces Mortality and Brain Damage in a Mouse Experimental Ischemic Stroke Model," 2020, Neurotherapeutics
  • "Nose-to-Brain Delivery of Dexamethasone: Biodistribution Studies in Mice," 2021, Journal of Pharmacology and Experimental Therapeutics
  • "Intranasal dexamethasone: a new clinical trial for the control of inflammation and neuroinflammation in COVID-19 patients," 2022, Trials
  • "To protect or to kill: A persisting Darwinian immune dilemma," 2022, Brain Behavior and Immunity
  • "Sympathetic-Immune Interactions during Different Types of Immune Challenge," 2023, NeuroImmunoModulation

Frequent coauthors collaborating with Besedovsky include:

  • Gladis Fragoso
  • Gabriela Meneses
  • Edda Sciutto
  • Adriana del Rey
  • Alejandro Espinosa

Frequent venues for publishing their research are:

  • Brain Behavior and Immunity
  • NeuroImmunoModulation
  • Neurotherapeutics
  • Journal of Pharmacology and Experimental Therapeutics
  • Trials

Best Publications

  • Immune-neuro-endocrine interactions: facts and hypotheses.

    H O Besedovsky;A del Rey

  • Immunoregulatory feedback between interleukin-1 and glucocorticoid hormones

    H Besedovsky;A del Rey;E Sorkin;CA Dinarello

  • A neuromodulatory role of interleukin-1β in the hippocampus

    H Schneider;F Pitossi;Detlef Balschun;A Wagner

  • The immune response evokes changes in brain noradrenergic neurons

    H Besedovsky;A del Rey;E Sorkin;M Da Prada

  • Changes in blood hormone levels during the immune response.

    H Besedovsky;E Sorkin;M Keller;J Müller

  • Microglial activation with atypical proinflammatory cytokine expression in a rat model of Parkinson's disease.

    Amaicha M. Depino;Chris Earl;Elke Kaczmarczyk;Carina Ferrari

  • What do the immune system and the brain know about each other

    Hugo O. Besedovsky;Adriana E. del Rey;Ernst Sorkin

  • Physiology of psychoneuroimmunology: a personal view.

    Hugo O. Besedovsky;Adriana del Rey

  • Induction of cytokine transcripts in the central nervous system and pituitary following peripheral administration of endotoxin to mice

    Fernando Pitossi;Adriana del Rey;Alexa Kabiersch;Hugo Besedovsky

  • Lymphokine-containing supernatants from con A-stimulated cells increase corticosterone blood levels.

    H O Besedovsky;A del Rey;E Sorkin

  • A cytokine network involving brain-borne IL-1β, IL-1ra, IL-18, IL-6, and TNFα operates during long-term potentiation and learning.

    Adriana del Rey;Detlef Balschun;Wolfram Wetzel;Anke Randolf

  • Neuroendocrine, sympathetic and metabolic responses induced by interleukin-1.

    Frank Berkenbosch;Dimphena E.C. de Goeij;Adriana del Rey;Hugo O. Besedovsky

  • The cytokine-HPA axis feed-back circuit.

    H.O. Besedovsky;A. del Rey

  • Interleukin-1 induces changes in norepinephrine metabolism in the rat brain

    Unknown

  • Interleukin 1 affects glucose homeostasis.

    A. del Rey;H. Besedovsky

  • Lymphoid cells produce an immunoregulatory glucocorticoid increasing factor (GIF) acting through the pituitary gland.

    H O Besedovsky;A Del Rey;E Sorkin;W Lotz

  • Selective Depletion of Macrophages Prevents Pituitary-Adrenal Activation in Response to Subpyrogenic, but not to Pyrogenic, Doses of Bacterial Endotoxin in Rats

    Roel Derijk;Nico Van Rooijen;Fred J. H. Tilders;Hugo O. Besedovsky

  • Endogenous glucocorticoids cause thymus atrophy but are protective during acute Trypanosoma cruzi infection.

    Eduardo Roggero;Ana R Pérez;Maximiliano Tamae-Kakazu;Isabel Piazzon

  • Central and peripheral cytokines mediate immune-brain connectivity.

    Hugo O. Besedovsky;Adriana del Rey

  • Thymus atrophy during Trypanosoma cruzi infection is caused by an immuno-endocrine imbalance

    Ana Rosa Pérez;Eduardo Roggero;Alicia Nicora;Jorge Palazzi

  • Endocrine and cytokine responses in humans with pulmonary tuberculosis.

    Adriana del Rey;Carolina V. Mahuad;Verónica V. Bozza;Cristina Bogue

Frequent Co-Authors

Manfred Schedlowski
Manfred Schedlowski University of Duisburg-Essen
Rainer H. Straub
Rainer H. Straub University of Regensburg
Gladis Fragoso
Gladis Fragoso National Autonomous University of Mexico
Edda Sciutto
Edda Sciutto National Autonomous University of Mexico
Harald Engler
Harald Engler Essen University Hospital
A. Vania Apkarian
A. Vania Apkarian Northwestern University
William Rostène
William Rostène Institut de la Vision
Martin K.-H. Schäfer
Martin K.-H. Schäfer Philipp University of Marburg
Wilson Savino
Wilson Savino Oswaldo Cruz Foundation

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