World's Best Scientists 2026 revealed!
Hiroshi Ohshima

Hiroshi Ohshima

D-Index & Metrics

Biology and Biochemistry

D-Index
71
Citations
16296
World Ranking
6726
National Ranking
448

Overview

Hiroshi Ohshima was affiliated with the University of Shizuoka in Japan. Their research primarily focused on medicine, with significant work conducted in subfields such as physiology, cardiology and cardiovascular medicine, dermatology, biomedical engineering, and health, toxicology, and mutagenesis.

The scientist's work concentrated on topics that included spaceflight effects on biology, heart rate variability and autonomic control, climate change and health impacts, EEG and brain-computer interfaces, non-invasive vital sign monitoring, high altitude and hypoxia, and circadian rhythm and melatonin.

Frequent publication venues for their research comprised Scientific Reports, Research Square, JBMR Plus, and Skin Research and Technology. The scientific collaborator network included coauthors such as Kuniaki Otsuka, Germaine Cornélissen, Satoshi Furukawa, Yutaka Kubo, and Koichi Shibata.

Some of the recent notable papers authored or coauthored by Hiroshi Ohshima included:

  • Astronauts well-being and possibly anti-aging improved during long-duration spaceflight (2021, Scientific Reports)
  • Unconscious mind activates central cardiovascular network and promotes adaptation to microgravity possibly anti-aging during 1-year-long spaceflight (2022, Scientific Reports)
  • Bisphosphonate Use May Reduce the Risk of Urolithiasis in Astronauts on Long-Term Spaceflights (2021, JBMR Plus)
  • Methods for assessing change in brain plasticity at night and psychological resilience during daytime between repeated long-duration space missions (2023, Scientific Reports)
  • New solution of beauty problem by Staphylococcus hominis: Relevance between skin microbiome and skin condition in healthy subject (2021, Skin Research and Technology)

Best Publications

  • Chronic infections and inflammatory processes as cancer risk factors : possible role of nitric oxide in carcinogenesis

    H. Ohshima;H. Bartsch

  • Chemical basis of inflammation-induced carcinogenesis ☆

    Hiroshi Ohshima;Masayuki Tatemichi;Tomohiro Sawa

  • DNA damage induced by peroxynitrite: subsequent biological effects.

    Csaba Szabó;Hiroshi Ohshima

  • Quantitative estimation of endogenous nitrosation in humans by monitoring N-nitrosoproline excreted in the urine.

    Hiroshi Ohshima;Helmut Bartsch

  • Formation of 8-nitroguanine in DNA treated with peroxynitrite in vitro and its rapid removal from DNA by depurination

    Vladimir Yermilov;Julieta Rubio;Hiroshi Ohshima

  • Formation of 8-nitroguanine by the reaction of guanine with peroxynitrite in vitro

    Vladimir Yermilov;Julieta Rubio;Michel Becchi;Marlin D. Friesen

  • Inhibitors of endogenous nitrosation. Mechanisms and implications in human cancer prevention.

    Helmut Bartsch;Hiroshi Ohshima;Brigitte Pignatelli

  • Antioxidant and pro-oxidant actions of flavonoids: effects on DNA damage induced by nitric oxide, peroxynitrite and nitroxyl anion.

    Hiroshi Ohshima;Yumiko Yoshie;Sebastien Auriol;Isabelle Gilibert

  • Nitrotyrosine as a new marker for endogenous nitrosation and nitration of proteins

    H. Ohshima;M. Friesen;I. Brouet;H. Bartsch

  • Tobacco-specific and betel nut-specific N-nitroso compounds: occurrence in saliva and urine of betel quid chewers and formation in vitro by nitrosation of betel quid

    J. Nair;H. Ohshima;M. Friesen;A. Croisy

  • Nitrated and Oxidized Plasma Proteins in Smokers and Lung Cancer Patients

    Brigitte Pignatelli;Chun-Qi Li;Paolo Boffetta;Qiping Chen

  • Nitrative DNA damage in inflammation and its possible role in carcinogenesis

    Tomohiro Sawa;Hiroshi Ohshima

  • Nitric Oxide Induces Conformational and Functional Modifications of Wild-Type p53 Tumor Suppressor Protein

    Sylvie Calmels;Pierre Hainaut;Hiroshi Ohshima

  • Effects of carbon dioxide/bicarbonate on induction of DNA single-strand breaks and formation of 8-nitroguanine, 8-oxoguanine and base-propenal mediated by peroxynitrite

    Vladimir Yermilov;Yumiko Yoshie;Julieta Rubio;Hiroshi Ohshima

  • Prevention of human cancer by modulation of chronic inflammatory processes.

    Hiroshi Ohshima;Hiroshi Tazawa;Bakary S. Sylla;Tomohiro Sawa

  • Expression of nitric oxide synthase isoforms in bone and bone cell cultures.

    Miep H. Helfrich;Deborah E. Evans;Peter S. Grabowski;Peter S. Grabowski;Jennifer S. Pollock

  • Suppression of Intestinal Polyposis in ApcMin/+ Mice by Inhibiting Nitric Oxide Production

    Byeongwoo Ahn;Hiroshi Ohshima

  • Urinary excretion of N-nitrosamino acids and nitrate by inhabitants of high- and low-risk areas for esophageal cancer in northern China: endogenous formation of nitrosoproline and its inhibition by vitamin C

    Shih-Hsin Lu;Hiroshi Ohshima;Hua-Ming Fu;Yuan Tian

  • Chlorination of Guanosine and Other Nucleosides by Hypochlorous Acid and Myeloperoxidase of Activated Human Neutrophils: CATALYSIS BY NICOTINE AND TRIMETHYLAMINE *

    Mitsuharu Masuda;Mitsuharu Masuda;Toshinori Suzuki;Marlin D. Friesen;Jean Luc Ravanat

  • Quantitative Estimation of Endogenous Nitrosation in Humans by Monitoring /V-Nitrosoproline Excreted in the Urine1

    Hiroshi Ohshima;Helmut Bartsch

Frequent Co-Authors

Helmut Bartsch
Helmut Bartsch German Cancer Research Center
Pierre Hainaut
Pierre Hainaut Grenoble Alpes University
László Virág
László Virág University of Debrecen
Csaba Szabó
Csaba Szabó University of Fribourg
Martin Crespi
Martin Crespi University of Paris-Saclay
Yoshimasa Nakamura
Yoshimasa Nakamura Okayama University
Kunio Kitahama
Kunio Kitahama Tokyo Metropolitan Institute of Medical Science
Shinya Toyokuni
Shinya Toyokuni Nagoya University
Hiroyasu Esumi
Hiroyasu Esumi Tokyo University of Science
Nubia Muñoz
Nubia Muñoz International Agency For Research On Cancer

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