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Hideki Yamamoto

Hideki Yamamoto

D-Index & Metrics

Biology and Biochemistry

D-Index
53
Citations
14442
World Ranking
15967
National Ranking
1139

Overview

Hideki Yamamoto is affiliated with Osaka University in Japan and has contributed to the field of medicine with a focus on oncology and molecular biology. Their research encompasses several areas within cancer study and treatment, particularly relating to gastrointestinal tumors and pancreatic oncology.

The scientist's recent publications include the following:

  • Homologous Recombination Deficiencies and Hereditary Tumors (2021), International Journal of Molecular Sciences
  • The Dickkopf1 and FOXM1 positive feedback loop promotes tumor growth in pancreatic and esophageal cancers (2021), Oncogene
  • CKAP4 is a potential exosomal biomarker and therapeutic target for lung cancer (2023), Translational Lung Cancer Research
  • Newly developed humanized anti-CKAP4 antibody suppresses pancreatic cancer growth by inhibiting DKK1-CKAP4 signaling (2024), Cancer Science
  • Genotypes and phenotypes of neurofibromatosis type 1 patients in Japan: A Hereditary Tumor Cohort Study (2024), Human Genome Variation

Yamamoto frequently collaborates with several researchers in their field, including:

  • Daisuke Ennishi (8 collaborations)
  • Toshiki Ozato (7 collaborations)
  • Yoshiyasu Kono (7 collaborations)
  • Motoyuki Otsuka (7 collaborations)
  • Akira Hirasawa (6 collaborations)

The prominent venues where Yamamoto publishes include:

  • European Journal of Cancer (2 publications)
  • Journal of Clinical Oncology (2 publications)
  • International Journal of Molecular Sciences (1 publication)
  • Translational Lung Cancer Research (1 publication)
  • Oncogene (1 publication)

Their main fields of study cover:

  • Medicine (30 publications)

Within this broad field, Yamamoto's work is concentrated in several subfields, including:

  • Oncology (7 publications)
  • Molecular Biology (5 publications)
  • Pulmonary and Respiratory Medicine (5 publications)
  • Gastroenterology (4 publications)
  • Surgery (3 publications)

Key research topics explored by Yamamoto include:

  • Gastrointestinal Tumor Research and Treatment (8 publications)
  • Pancreatic and Hepatic Oncology Research (6 publications)
  • Cholangiocarcinoma and Gallbladder Cancer Studies (6 publications)
  • Neuroendocrine Tumor Research Advances (6 publications)
  • Sarcoma Diagnosis and Treatment (4 publications)
  • Gastric Cancer Management and Outcomes (4 publications)
  • Genetic factors in colorectal cancer (4 publications)

Best Publications

  • Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK‐3β and β‐catenin and promotes GSK‐3β‐dependent phosphorylation of β‐catenin

    Satoshi Ikeda;Shosei Kishida;Hideki Yamamoto;Hiroshi Murai

  • Axin, a Negative Regulator of the Wnt Signaling Pathway, Directly Interacts with Adenomatous Polyposis Coli and Regulates the Stabilization of β-Catenin

    Shosei Kishida;Hideki Yamamoto;Satoshi Ikeda;Michiko Kishida

  • Expression of Wnt-5a is correlated with aggressiveness of gastric cancer by stimulating cell migration and invasion.

    Manabu Kurayoshi;Naohide Oue;Hideki Yamamoto;Michiko Kishida

  • DIX Domains of Dvl and Axin Are Necessary for Protein Interactions and Their Ability To Regulate β-Catenin Stability

    Shosei Kishida;Shosei Kishida;Hideki Yamamoto;Shin-ichiro Hino;Satoshi Ikeda

  • Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3beta regulates its stability.

    Hideki Yamamoto;Shosei Kishida;Shosei Kishida;Michiko Kishida;Satoshi Ikeda

  • Caveolin Is Necessary for Wnt-3a-Dependent Internalization of LRP6 and Accumulation of β-Catenin

    Hideki Yamamoto;Hideyuki Komekado;Akira Kikuchi

  • Wnt5a regulates distinct signalling pathways by binding to Frizzled2

    Akira Sato;Hideki Yamamoto;Hiroshi Sakane;Hirofumi Koyama

  • Activation of AMP-activated Protein Kinase Induces p53-dependent Apoptotic Cell Death in Response to Energetic Stress

    Rintaro Okoshi;Toshinori Ozaki;Hideki Yamamoto;Kiyohiro Ando

  • Multiplicity of the interactions of Wnt proteins and their receptors

    Akira Kikuchi;Hideki Yamamoto;Shosei Kishida

  • Polo-like kinase 1 (Plk1) inhibits p53 function by physical interaction and phosphorylation.

    Kiyohiro Ando;Toshinori Ozaki;Hideki Yamamoto;Kazushige Furuya

  • New insights into the mechanism of Wnt signaling pathway activation.

    Akira Kikuchi;Hideki Yamamoto;Akira Sato;Shinji Matsumoto

  • Post-translational palmitoylation and glycosylation of Wnt-5a are necessary for its signalling

    Manabu Kurayoshi;Hideki Yamamoto;Shunsuke Izumi;Akira Kikuchi

  • Selective activation mechanisms of Wnt signaling pathways

    Akira Kikuchi;Hideki Yamamoto;Akira Sato

  • Wnt3a and Dkk1 Regulate Distinct Internalization Pathways of LRP6 to Tune the Activation of β-Catenin Signaling

    Hideki Yamamoto;Hiroshi Sakane;Tatsuo Michiue;Akira Kikuchi

  • Wnt5a signaling is involved in the aggressiveness of prostate cancer and expression of metalloproteinase.

    H Yamamoto;N Oue;A Sato;Y Hasegawa

  • Regulation of Wnt signaling by protein-protein interaction and post-translational modifications

    Akira Kikuchi;Shosei Kishida;Hideki Yamamoto

  • Glycosylation and palmitoylation of Wnt-3a are coupled to produce an active form of Wnt-3a

    Hideyuki Komekado;Hideki Yamamoto;Tsutomu Chiba;Akira Kikuchi

  • Axil, a Member of the Axin Family, Interacts with Both Glycogen Synthase Kinase 3β and β-Catenin and Inhibits Axis Formation of Xenopus Embryos

    Hideki Yamamoto;Shosei Kishida;Takaaki Uochi;Satoshi Ikeda

  • Sumoylation is involved in β‐catenin‐dependent activation of Tcf‐4

    Hideki Yamamoto;Motomasa Ihara;Yoshiharu Matsuura;Akira Kikuchi

  • Active and water-soluble form of lipidated Wnt protein is maintained by a serum glycoprotein afamin/α-albumin

    Emiko Mihara;Hidenori Hirai;Hideki Yamamoto;Keiko Tamura-Kawakami

Frequent Co-Authors

Akira Kikuchi
Akira Kikuchi Osaka University
Katsuya Nagai
Katsuya Nagai Osaka University
Wataru Yasui
Wataru Yasui Hiroshima University
Makoto Asashima
Makoto Asashima Teikyo University
Toshio Ogihara
Toshio Ogihara Osaka University
Satoru Todo
Satoru Todo Hokkaido University
Toshifumi Takao
Toshifumi Takao Osaka University
Yuko Fukata
Yuko Fukata National Institutes of Natural Sciences
Hirokazu Kimura
Hirokazu Kimura RMIT University

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