What is he best known for?
The fields of study he is best known for:
- Gene
- Internal medicine
- Cancer
Hideki Yamamoto mainly investigates Wnt signaling pathway, Phosphorylation, Cell biology, LRP6 and Molecular biology.
His Wnt signaling pathway study combines topics in areas such as Secretion and Cancer research.
His Phosphorylation research includes elements of Beta-catenin, Axin Protein, Catenin, Gene knockdown and Carbohydrate metabolism.
Cell biology is closely attributed to Internalization in his study.
His study ties his expertise on LRP5 together with the subject of LRP6.
Hideki Yamamoto has researched Molecular biology in several fields, including Enzyme activator, Apoptosis, Downregulation and upregulation and Protein kinase A.
His most cited work include:
- Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK‐3β and β‐catenin and promotes GSK‐3β‐dependent phosphorylation of β‐catenin (1125 citations)
- Axin, a Negative Regulator of the Wnt Signaling Pathway, Directly Interacts with Adenomatous Polyposis Coli and Regulates the Stabilization of β-Catenin (451 citations)
- Expression of Wnt-5a is correlated with aggressiveness of gastric cancer by stimulating cell migration and invasion. (371 citations)
What are the main themes of his work throughout his whole career to date?
Hideki Yamamoto mainly focuses on Wnt signaling pathway, Cell biology, Internal medicine, Molecular biology and Endocrinology.
In his study, Axin Protein is strongly linked to Phosphorylation, which falls under the umbrella field of Wnt signaling pathway.
Hideki Yamamoto works mostly in the field of Cell biology, limiting it down to concerns involving Secretion and, occasionally, Glycosylation.
His Internal medicine research incorporates elements of Allele and Oncology.
His Molecular biology research integrates issues from Apoptosis, Catenin, Downregulation and upregulation, SUMO protein and Adenomatous polyposis coli.
His LRP6 research incorporates themes from Endocytic cycle, Plasma protein binding and Frizzled.
He most often published in these fields:
- Wnt signaling pathway (28.57%)
- Cell biology (24.81%)
- Internal medicine (22.56%)
What were the highlights of his more recent work (between 2012-2021)?
- Cancer research (15.79%)
- Cell biology (24.81%)
- Wnt signaling pathway (28.57%)
In recent papers he was focusing on the following fields of study:
Cancer research, Cell biology, Wnt signaling pathway, Clathrin and Secretion are his primary areas of study.
His research in Cancer research intersects with topics in Protein kinase B, Cancer cell, DNA mismatch repair and Cell invasion, Metastasis.
His study in Cell biology is interdisciplinary in nature, drawing from both Cell, Endocytosis, A549 cell and Cell growth.
His study in LRP6 and LRP5 is carried out as part of his studies in Wnt signaling pathway.
His research integrates issues of PI3K/AKT/mTOR pathway and DKK1 in his study of LRP6.
His Secretion research is multidisciplinary, incorporating elements of Cyst, Receptor, Signal transducing adaptor protein, WNT5A and Apoptosis.
Between 2012 and 2021, his most popular works were:
- Active and water-soluble form of lipidated Wnt protein is maintained by a serum glycoprotein afamin/α-albumin (92 citations)
- Wnt5b-associated exosomes promote cancer cell migration and proliferation. (64 citations)
- The apical and basolateral secretion of Wnt11 and Wnt3a in polarized epithelial cells is regulated by different mechanisms. (48 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Internal medicine
- Cancer
Hideki Yamamoto spends much of his time researching Cancer research, Cell biology, Wnt signaling pathway, Cancer cell and Cell growth.
His Cancer research research integrates issues from Tyrosine, Protein tyrosine phosphatase, Protein kinase B and Targeted therapy.
His studies in Cell biology integrate themes in fields like Epithelial polarity, Secretion, Immunology, A549 cell and Immunoelectron microscopy.
His Secretion study integrates concerns from other disciplines, such as Transmembrane protein, Glycan, Glycosylation and Clathrin.
His Wnt signaling pathway study incorporates themes from Albumin and Glycoprotein.
His biological study deals with issues like Cancer stem cell, which deal with fields such as Pathology, Cluster of differentiation, CD44 and Cell migration.
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