Hideki Yamamoto mainly investigates Wnt signaling pathway, Phosphorylation, Cell biology, LRP6 and Molecular biology. His Wnt signaling pathway study combines topics in areas such as Secretion and Cancer research. His Phosphorylation research includes elements of Beta-catenin, Axin Protein, Catenin, Gene knockdown and Carbohydrate metabolism.
Cell biology is closely attributed to Internalization in his study. His study ties his expertise on LRP5 together with the subject of LRP6. Hideki Yamamoto has researched Molecular biology in several fields, including Enzyme activator, Apoptosis, Downregulation and upregulation and Protein kinase A.
Hideki Yamamoto mainly focuses on Wnt signaling pathway, Cell biology, Internal medicine, Molecular biology and Endocrinology. In his study, Axin Protein is strongly linked to Phosphorylation, which falls under the umbrella field of Wnt signaling pathway. Hideki Yamamoto works mostly in the field of Cell biology, limiting it down to concerns involving Secretion and, occasionally, Glycosylation.
His Internal medicine research incorporates elements of Allele and Oncology. His Molecular biology research integrates issues from Apoptosis, Catenin, Downregulation and upregulation, SUMO protein and Adenomatous polyposis coli. His LRP6 research incorporates themes from Endocytic cycle, Plasma protein binding and Frizzled.
Cancer research, Cell biology, Wnt signaling pathway, Clathrin and Secretion are his primary areas of study. His research in Cancer research intersects with topics in Protein kinase B, Cancer cell, DNA mismatch repair and Cell invasion, Metastasis. His study in Cell biology is interdisciplinary in nature, drawing from both Cell, Endocytosis, A549 cell and Cell growth.
His study in LRP6 and LRP5 is carried out as part of his studies in Wnt signaling pathway. His research integrates issues of PI3K/AKT/mTOR pathway and DKK1 in his study of LRP6. His Secretion research is multidisciplinary, incorporating elements of Cyst, Receptor, Signal transducing adaptor protein, WNT5A and Apoptosis.
Hideki Yamamoto spends much of his time researching Cancer research, Cell biology, Wnt signaling pathway, Cancer cell and Cell growth. His Cancer research research integrates issues from Tyrosine, Protein tyrosine phosphatase, Protein kinase B and Targeted therapy. His studies in Cell biology integrate themes in fields like Epithelial polarity, Secretion, Immunology, A549 cell and Immunoelectron microscopy.
His Secretion study integrates concerns from other disciplines, such as Transmembrane protein, Glycan, Glycosylation and Clathrin. His Wnt signaling pathway study incorporates themes from Albumin and Glycoprotein. His biological study deals with issues like Cancer stem cell, which deal with fields such as Pathology, Cluster of differentiation, CD44 and Cell migration.
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Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK‐3β and β‐catenin and promotes GSK‐3β‐dependent phosphorylation of β‐catenin
Satoshi Ikeda;Shosei Kishida;Hideki Yamamoto;Hiroshi Murai.
The EMBO Journal (1998)
Axin, a Negative Regulator of the Wnt Signaling Pathway, Directly Interacts with Adenomatous Polyposis Coli and Regulates the Stabilization of β-Catenin
Shosei Kishida;Hideki Yamamoto;Satoshi Ikeda;Michiko Kishida.
Journal of Biological Chemistry (1998)
Expression of Wnt-5a is correlated with aggressiveness of gastric cancer by stimulating cell migration and invasion.
Manabu Kurayoshi;Naohide Oue;Hideki Yamamoto;Michiko Kishida.
Cancer Research (2006)
DIX Domains of Dvl and Axin Are Necessary for Protein Interactions and Their Ability To Regulate β-Catenin Stability
Shosei Kishida;Shosei Kishida;Hideki Yamamoto;Shin-ichiro Hino;Satoshi Ikeda.
Molecular and Cellular Biology (1999)
Phosphorylation of axin, a Wnt signal negative regulator, by glycogen synthase kinase-3beta regulates its stability.
Hideki Yamamoto;Shosei Kishida;Shosei Kishida;Michiko Kishida;Satoshi Ikeda.
Journal of Biological Chemistry (1999)
Caveolin Is Necessary for Wnt-3a-Dependent Internalization of LRP6 and Accumulation of β-Catenin
Hideki Yamamoto;Hideyuki Komekado;Akira Kikuchi.
Developmental Cell (2006)
Wnt5a regulates distinct signalling pathways by binding to Frizzled2
Akira Sato;Hideki Yamamoto;Hiroshi Sakane;Hirofumi Koyama.
The EMBO Journal (2010)
Activation of AMP-activated Protein Kinase Induces p53-dependent Apoptotic Cell Death in Response to Energetic Stress
Rintaro Okoshi;Toshinori Ozaki;Hideki Yamamoto;Kiyohiro Ando.
Journal of Biological Chemistry (2008)
Multiplicity of the interactions of Wnt proteins and their receptors
Akira Kikuchi;Hideki Yamamoto;Shosei Kishida.
Cellular Signalling (2007)
Polo-like kinase 1 (Plk1) inhibits p53 function by physical interaction and phosphorylation.
Kiyohiro Ando;Toshinori Ozaki;Hideki Yamamoto;Kazushige Furuya.
Journal of Biological Chemistry (2004)
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