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Neuroscience

D-Index
77
Citations
18707
World Ranking
1858
National Ranking
168

Overview

Hans-Georg Schaible is affiliated with Friedrich Schiller University Jena in Germany, contributing extensively to the field of Medicine, particularly focusing on Physiology, Psychiatry and Mental Health, Pharmacology, Rheumatology, and Cellular and Molecular Neuroscience.

The scientist's research spans several main topics, including Pain Mechanisms and Treatments, Osteoarthritis Treatment and Mechanisms, Fibromyalgia and Chronic Fatigue Syndrome Research, Receptor Mechanisms and Signaling, Inflammatory Mediators and NSAID Effects, Neuropeptides and Animal Physiology, and Musculoskeletal Pain and Rehabilitation.

Frequent publication venues where Schaible's work appears encompass Der Schmerz, Osteoarthritis and Cartilage, Journal of Neurochemistry, International Journal of Molecular Sciences, and Experimental Neurology.

Selected recent papers authored include:

  • Regulation of acute reflectory hyperinflammation in viral and other diseases by means of stellate ganglion block. A conceptual view with a focus on Covid-19, 2021, Autonomic Neuroscience
  • Impact of Diabetes Mellitus on Knee Osteoarthritis Pain and Physical and Mental Status: Data From the Osteoarthritis Initiative, 2020, Arthritis Care & Research
  • Oncostatin M induces hyperalgesic priming and amplifies signaling of cAMP to ERK by RapGEF2 and PKA, 2020, Journal of Neurochemistry
  • Inhibition of Inducible Nitric Oxide Synthase Prevents IL-1β-Induced Mitochondrial Dysfunction in Human Chondrocytes, 2021, International Journal of Molecular Sciences
  • Spinal pain processing in arthritis: Neuron and glia (inter)actions, 2022, Journal of Neurochemistry

Schaible has collaborated frequently with several researchers throughout their career. Notable co-authors include Annett Eitner, Christian König, Andrea Ebersberger, Frank Richter, and Gunther O. Hofmann.

Best Publications

  • Afferent and spinal mechanisms of joint pain

    Unknown

  • Descending control of persistent pain: inhibitory or facilitatory?

    Horacio Vanegas;Hans-Georg Schaible

  • Prostaglandins and cycloxygenases in the spinal cord

    Horacio Vanegas;Hans-Georg Schaible

  • Effects of an experimental arthritis on the sensory properties of fine articular afferent units.

    H. G. Schaible;R. F. Schmidt

  • Time course of mechanosensitivity changes in articular afferents during a developing experimental arthritis.

    H. G. Schaible;R. F. Schmidt

  • Nociceptive neurons detect cytokines in arthritis

    Unknown

  • A de novo gain-of-function mutation in SCN11A causes loss of pain perception

    Enrico Leipold;Lutz Liebmann;G Christoph Korenke;Theresa Heinrich

  • Excitation and sensitization of fine articular afferents from cat's knee joint by prostaglandin E2.

    H G Schaible;R F Schmidt

  • Release of immunoreactive substance P in the spinal cord during development of acute arthritis in the knee joint of the cat: a study with antibody microprobes.

    H.-G. Schaible;B. Jarrott;P.J. Hope;A.W. Duggan

  • Effects of antagonists to high-threshold calcium channels upon spinal mechanisms of pain, hyperalgesia and allodynia.

    Horacio Vanegas;Hans-Georg Schaible

  • Evidence for a central component in the sensitization of spinal neurons with joint input during development of acute arthritis in cat's knee.

    V. Neugebauer;H. G. Schaible

  • Release, spread and persistence of immunoreactive neurokinin A in the dorsal horn of the cat following noxious cutaneous stimulation. Studies with antibody microprobes

    A.W. Duggan;P.J. Hope;B. Jarrott;H.-G. Schaible

  • Mechanisms of Chronic Pain in Osteoarthritis

    Unknown

  • Sensitization of unmyelinated sensory fibers of the joint nerve to mechanical stimuli by interleukin-6 in the rat: an inflammatory mechanism of joint pain.

    Unknown

  • Mechanical sensitivity of group III and IV afferents from posterior articular nerve in normal and inflamed cat knee.

    Unknown

  • Enhancement of the responses of ascending tract cells in the cat spinal cord by acute inflammation of the knee joint.

    H. G. Schaible;R. F. Schmidt;W. D. Willis

  • Joint pain

    Hans-Georg Schaible;Frank Richter;Andrea Ebersberger;Michael K. Boettger

  • Requirement of metabotropic glutamate receptors for the generation of inflammation-evoked hyperexcitability in rat spinal cord neurons.

    Volker Neugebauer;Thomas Lücke;Hans‐Georg Schaible

  • Changes in tonic descending inhibition of spinal neurons with articular input during the development of acute arthritis in the cat

    H. G. Schaible;V. Neugebauer;F. Cervero;R. F. Schmidt

  • Activation of groups III and IV sensory units in medial articular nerve by local mechanical stimulation of knee joint.

    H G Schaible;R F Schmidt

  • Antinociceptive effects of tumor necrosis factor alpha neutralization in a rat model of antigen-induced arthritis: evidence of a neuronal target.

    Michael K. Boettger;Susanne Hensellek;Frank Richter;Mieczyslaw Gajda

  • Mechanisms of Osteoarthritic Pain. Studies in Humans and Experimental Models.

    Annett Eitner;Gunther O. Hofmann;Hans-Georg Schaible

  • Opiates inhibit the discharges of fine afferent units from inflamed knee joint of the cat.

    N.J.W. Russell;H.-G. Schaible;R.F. Schmidt

  • Discharge characteristics of fine medial articular afferents at rest and during passive movements of inflamed knee joints

    Richard E. Coggeshall;Kyung Ah Park Hong;Lauren A. Langford;Hans Georg Schaible

  • The cytokine TNFalpha increases the proportion of DRG neurones expressing the TRPV1 receptor via the TNFR1 receptor and ERK activation.

    Susanne Hensellek;Patrice Brell;Hans-Georg Schaible;Rolf Bräuer

  • Mechanisms of Pain in Arthritis

    Unknown

Frequent Co-Authors

Robert F. Schmidt
Robert F. Schmidt University of Würzburg
Horacio Vanegas
Horacio Vanegas Instituto Venezolano de Investigaciones Científicas
Vincent Timmerman
Vincent Timmerman University of Antwerp
Wilfrid Jänig
Wilfrid Jänig Kiel University
Herta Flor
Herta Flor Heidelberg University
Peter Nürnberg
Peter Nürnberg University of Cologne
Janine Altmüller
Janine Altmüller University of Cologne
Ralf Schneggenburger
Ralf Schneggenburger École Polytechnique Fédérale de Lausanne
Peter De Jonghe
Peter De Jonghe University of Antwerp
Mark Sullivan
Mark Sullivan University of Southampton

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