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Overview

Giuliano Freddi is a researcher affiliated with the Stazione Sperimentale per la Seta in Italy. Their work primarily explores the field of Materials Science, with a focus on several subfields including Biomaterials, Orthopedics and Sports Medicine, Molecular Biology, Biomedical Engineering, and Cellular and Molecular Neuroscience.

The main topics addressed in Freddi's research involve silk-based biomaterials and applications, electrospun nanofibers in biomedical applications, tendon structure and treatment, bone tissue engineering materials, nerve injury and regeneration, polymer surface interaction studies, and biochemical and structural characterization.

Freddi has contributed to numerous publications, including papers covering diverse aspects of silk fibroin and its biomedical implications. Notable publications include:

  • Exosomes of adult human fibroblasts cultured on 3D silk fibroin nonwovens intensely stimulate neoangiogenesis (2021, Burns & Trauma)
  • Preclinical Validation of SilkBridgeTM for Peripheral Nerve Regeneration (2020, Frontiers in Bioengineering and Biotechnology)
  • Electrospun Silk Fibroin Scaffolds for Tissue Regeneration: Chemical, Structural, and Toxicological Implications of the Formic Acid-Silk Fibroin Interaction (2022, Frontiers in Bioengineering and Biotechnology)
  • Peptide-Enriched Silk Fibroin Sponge and Trabecular Titanium Composites to Enhance Bone Ingrowth of Prosthetic Implants in an Ovine Model of Bone Gaps (2020, Frontiers in Bioengineering and Biotechnology)
  • In-vivo evaluation of silk fibroin small-diameter vascular grafts: state of art of preclinical studies and animal models (2023, Frontiers in Surgery)

Freddi's frequent coauthors include Antonio Alessandrino, Marco Biagiotti, Giulia Alessandra Bassani, Anna Chiarini, and Ilaria Dal Prà.

The researcher has published extensively in several venues, with a particular concentration in:

  • Frontiers in Bioengineering and Biotechnology
  • Burns & Trauma
  • Frontiers in Surgery
  • ACS Applied Bio Materials
  • Cells

Best Publications

  • In vitro evaluation of the inflammatory potential of the silk fibroin.

    Matteo Santin;Antonella Motta;Giuliano Freddi;Mario Cannas

  • Biodegradation of Bombyx mori silk fibroin fibers and films

    Takayuki Arai;Giuliano Freddi;Riccardo Innocenti;Masuhiro Tsukada

  • Biodegradable Materials Based on Silk Fibroin and Keratin

    Andreia Vasconcelos;Giuliano Freddi;Artur Cavaco-Paulo

  • Enzymatic surface hydrolysis of PET : effect of structural diversity on kinetic properties of cutinases from thermobifida

    Enrique Herrero Acero;Doris Ribitsch;Georg Steinkellner;Karl Gruber

  • Structural changes of silk fibroin membranes induced by immersion in methanol aqueous solutions

    Masuhiro Tsukada;Yoko Gotoh;Masanobu Nagura;Norihiko Minoura

  • De novo engineering of reticular connective tissue in vivo by silk fibroin nonwoven materials.

    Ilaria Dal Pra;Giuliano Freddi;Jasminka Minic;Anna Chiarini

  • A fully organic retinal prosthesis restores vision in a rat model of degenerative blindness

    José Fernando Maya-Vetencourt;Diego Ghezzi;Diego Ghezzi;Maria Rosa Antognazza;Elisabetta Colombo

  • Silk fibroin/cellulose blend films : preparation, structure, and physical properties

    Giuliano Freddi;Maria Romanò;Maria Rosaria Massafra;Masuhiro Tsukada

  • Surface structure and properties of poly-(ethylene terephthalate) hydrolyzed by alkali and cutinase

    Ilaria Donelli;Giuliano Freddi;Vincent A. Nierstrasz;Paola Taddei

  • Structure and compatibility of poly(vinyl alcohol)‐silk fibroin (PVA/SA) blend films

    Masuhiro Tsukada;Giuliano Freddi;John S. Crighton

  • Compliant electrospun silk fibroin tubes for small vessel bypass grafting

    Benedetto Marelli;Antonio Alessandrino;Antonio Alessandrino;Silvia Farè;Giuliano Freddi

  • Hydrolysis of polyethyleneterephthalate by p-nitrobenzylesterase from Bacillus subtilis.

    Doris Ribitsch;Sonja Heumann;Eva Trotscha;Enrique Herrero Acero

  • Physical properties and dyeability of silk fibers degummed with citric acid.

    Md. Majibur Rahman Khan;Masuhiro Tsukada;Yasuo Gotoh;Hideaki Morikawa

  • Vascular Tissue Engineering: Recent Advances in Small Diameter Blood Vessel Regeneration

    Valentina Catto;Silvia Farè;Giuliano Freddi;Maria Cristina Tanzi

  • Preparation and application of porous silk fibroin materials

    Masuhiro Tsukada;Giuliano Freddi;Norihiko Minoura;Giulia Allara

  • Raman spectroscopic characterization of Bombyx mori silk fibroin: Raman spectrum of Silk I

    P. Monti;P. Taddei;G. Freddi;T. Asakura

  • Enzymatic surface modification and functionalization of PET: A water contact angle, FTIR, and fluorescence spectroscopy study

    Ilaria Donelli;Paola Taddei;Philippe F. Smet;Dirk Poelman

  • Structure and physical properties of silk fibroin/polyacrylamide blend films

    Giuliano Freddi;Masuhiro Tsukada;Silvia Beretta

  • Swelling and dissolution of silk fibroin (Bombyx mori) in N-methyl morpholine N-oxide.

    G Freddi;G Pessina;M Tsukada

  • Tyrosinase-catalyzed grafting of sericin peptides onto chitosan and production of protein-polysaccharide bioconjugates.

    Anna Anghileri;Raija Lantto;Kristiina Kruus;Cristina Arosio

  • Small diameter electrospun silk fibroin vascular grafts: Mechanical properties, in vitro biodegradability, and in vivo biocompatibility.

    Valentina Catto;Silvia Farè;Irene Cattaneo;Marina Figliuzzi

  • Tyrosinase-catalyzed modification of Bombyx mori silk fibroin: grafting of chitosan under heterogeneous reaction conditions.

    Giuliano Freddi;Anna Anghileri;Sandra Sampaio;Johanna Buchert

Frequent Co-Authors

Paola Taddei
Paola Taddei University of Bologna
Maria Cristina Tanzi
Maria Cristina Tanzi Polytechnic University of Milan
Showan N. Nazhat
Showan N. Nazhat McGill University
Silvia Farè
Silvia Farè Polytechnic University of Milan
Dirk Poelman
Dirk Poelman Ghent University
Fabio Benfenati
Fabio Benfenati Italian Institute of Technology
Jake E. Barralet
Jake E. Barralet McGill University
Guglielmo Lanzani
Guglielmo Lanzani Italian Institute of Technology
Artur Cavaco-Paulo
Artur Cavaco-Paulo University of Minho

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