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Neuroscience

D-Index
46
Citations
10533
World Ranking
6616
National Ranking
2872

Overview

Gavin Rumbaugh is affiliated with the Scripps Research Institute in the United States. Their research spans significant areas within biochemistry, genetics, molecular biology, and neuroscience, with a particular focus on molecular biology and cellular and molecular neuroscience.

The scientist has contributed extensively to the understanding of neural development, gene regulation, and neuropharmacology. Their main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Neuroscience

Within these broader disciplines, Rumbaugh's work further explores subfields such as:

  • Molecular Biology
  • Cellular and Molecular Neuroscience
  • Cell Biology
  • Cognitive Neuroscience
  • Genetics

Their research covers various topics including:

  • Neuroscience and Neuropharmacology Research
  • Genetics and Neurodevelopmental Disorders
  • Neuroscience and Neural Engineering
  • RNA Research and Splicing
  • Cellular transport and secretion
  • Memory and Neural Mechanisms
  • Cardiomyopathy and Myosin Studies

Rumbaugh's publication record includes multiple papers in high-impact journals and respected venues. Some of the notable recent papers include:

  • "Vagal sensory neurons mediate the Bezold-Jarisch reflex and induce syncope", 2023, Nature
  • "Design, Optimization, and Study of Small Molecules That Target Tau Pre-mRNA and Affect Splicing", 2020, Journal of the American Chemical Society
  • "SYNGAP1 Controls the Maturation of Dendrites, Synaptic Function, and Network Activity in Developing Human Neurons", 2020, Journal of Neuroscience
  • "Non-synaptic function of the autism spectrum disorder-associated gene SYNGAP1 in cortical neurogenesis", 2023, Nature Neuroscience
  • "SynGAP splice variants display heterogeneous spatio-temporal expression and subcellular distribution in the developing mammalian brain", 2020, Journal of Neurochemistry

Frequent publication venues for Rumbaugh include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Neuroscience
  • Cell
  • Neuro-Oncology
  • Nature

Collaboration has been a key component of Rumbaugh's scientific work, with frequent coauthors such as:

  • Courtney A. Miller
  • László Radnai
  • Theodore M. Kamenecka
  • Camilo Rojas
  • Thomas Vaissière

Best Publications

  • Phosphorylation of the AMPA Receptor GluR1 Subunit Is Required for Synaptic Plasticity and Retention of Spatial Memory

    Hey Kyoung Lee;Kogo Takamiya;Jung Soo Han;Hengye Man

  • Arc/Arg3.1 Mediates Homeostatic Synaptic Scaling of AMPA Receptors

    Jason D. Shepherd;Gavin Rumbaugh;Jing Wu;Shoaib Chowdhury

  • Inhibitors of class 1 histone deacetylases reverse contextual memory deficits in a mouse model of Alzheimer's disease.

    Mark Kilgore;Courtney A Miller;Daniel M Fass;Daniel M Fass;Krista M Hennig;Krista M Hennig

  • Cortical DNA methylation maintains remote memory.

    Courtney A Miller;Courtney A Miller;Cristin F Gavin;Cristin F Gavin;Jason A White;R Ryley Parrish

  • Surface Mobility of Postsynaptic AMPARs Tunes Synaptic Transmission

    Martin Heine;Laurent Groc;Renato Frischknecht;Jean Claude Béïque

  • Pathogenic SYNGAP1 mutations impair cognitive development by disrupting maturation of dendritic spine synapses.

    James P. Clement;Massimiliano Aceti;Thomas K. Creson;Emin D. Ozkan

  • SynGAP regulates synaptic strength and mitogen-activated protein kinases in cultured neurons.

    Gavin Rumbaugh;J. Paige Adams;J. Paige Adams;Jee H. Kim;Richard L. Huganir

  • Differential regulation of AMPA receptor subunit trafficking by palmitoylation of two distinct sites.

    Takashi Hayashi;Gavin Rumbaugh;Richard L. Huganir

  • Distinct Synaptic and Extrasynaptic NMDA Receptors in Developing Cerebellar Granule Neurons

    Gavin Rumbaugh;Stefano Vicini

  • Synapse-Associated Protein-97 Isoform-Specific Regulation of Surface AMPA Receptors and Synaptic Function in Cultured Neurons

    Gavin Rumbaugh;Gek Ming Sia;Craig C. Garner;Richard L. Huganir

  • An interactive framework for whole-brain maps at cellular resolution

    Daniel Fürth;Thomas Vaissière;Ourania Tzortzi;Yang Xuan

  • Myosin IIb regulates actin dynamics during synaptic plasticity and memory formation.

    Christopher S. Rex;Cristin F. Gavin;Maria D. Rubio;Eniko A. Kramar

  • Interaction of the N-Terminal Domain of the AMPA Receptor GluR4 Subunit with the Neuronal Pentraxin NP1 Mediates GluR4 Synaptic Recruitment

    Gek Ming Sia;Jean Claude Béïque;Gavin Rumbaugh;Richard Cho

  • Synaptic evidence for the efficacy of spaced learning

    Enikö A. Kramár;Alex H. Babayan;Cristin F. Gavin;Conor D. Cox

  • C75, a Fatty Acid Synthase Inhibitor, Modulates AMP-activated Protein Kinase to Alter Neuronal Energy Metabolism

    Leslie E. Landree;Andrea L. Hanlon;David W. Strong;Gavin Rumbaugh

  • MicroRNA-182 regulates amygdala-dependent memory formation.

    Erica M. Griggs;Erica J. Young;Gavin Rumbaugh;Courtney A. Miller

  • Impaired NMDA receptor-mediated postsynaptic function and blunted NMDA receptor-dependent persistent pain in mice lacking postsynaptic density-93 protein.

    Yuan Xiang Tao;Gavin Rumbaugh;Guo Du Wang;Ronald S. Petralia

  • Reduced cognition in Syngap1 mutants is caused by isolated damage within developing forebrain excitatory neurons.

    Emin D. Ozkan;Thomas K. Creson;Enikö A. Kramár;Camilo Rojas

  • Reduced expression of the NMDA receptor-interacting protein SynGAP causes behavioral abnormalities that model symptoms of Schizophrenia.

    Xiaochuan Guo;Peter J Hamilton;Nicholas J Reish;J David Sweatt

  • Syngap1 haploinsufficiency damages a postnatal critical period of pyramidal cell structural maturation linked to cortical circuit assembly

    Massimiliano Aceti;Thomas K. Creson;Thomas Vaissiere;Camilo Rojas

  • Exon 5 and Spermine Regulate Deactivation of NMDA Receptor Subtypes

    Gavin Rumbaugh;Kate Prybylowski;Jian Feng Wang;Stefano Vicini

Frequent Co-Authors

Richard L. Huganir
Richard L. Huganir Johns Hopkins University School of Medicine
Eric Vermetten
Eric Vermetten Leiden University Medical Center
Stefano Vicini
Stefano Vicini Georgetown University Medical Center
J. David Sweatt
J. David Sweatt University of Alabama at Birmingham
Christine M. Gall
Christine M. Gall University of California, Irvine
Enikö A. Kramár
Enikö A. Kramár University of California, Irvine
Elbert Geuze
Elbert Geuze Utrecht University
Kerry J. Ressler
Kerry J. Ressler Harvard University
Marco P. Boks
Marco P. Boks University of Amsterdam
Jos C. S. Kleinjans
Jos C. S. Kleinjans Maastricht University

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