Donald S. Davies

Overview

Best Publications

• Clinical pharmacology and pharmacokinetics of clonidine.

  C. T. Dollery;D. S. Davies;G. H. Draffan;H. J. Dargie

  356
  Citations

• Pharmacokinetics and concentration‐effect relationships of intravenous and oral clonidine

  D. S. Davies;L. M. H. Wing;J. L. Reid;E. Neill

  356
  Citations

• Mechanisms of cell death

  Alan R. Boobis;Duncan J. Fawthrop;Donald S. Davies

  354
  Citations

• A form of cytochrome P450 in man, orthologous to form d in the rat, catalyses the O-deethylation of phenacetin and is inducible by cigarette smoking.

  D Sesardic;AR Boobis;RJ Edwards;DS Davies

  341
  Citations

• Meta-analysis of Studies of Alcohol and Breast Cancer with Consideration of the Methodological Issues

  Jane Key;Susan Hodgson;Rumana Z. Omar;Tina K. Jensen

  336
  Citations

• Furafylline is a potent and selective inhibitor of cytochrome P450IA2 in man.

  D Sesardic;AR Boobis;BP Murray;S Murray

  330
  Citations

• CYP1A2-catalyzed Conversion of Dietary Heterocyclic Amines to Their Proximate Carcinogens Is Their Major Route of Metabolism in Humans

  A R Boobis;A M Lynch;S Murray;R de la Torre

  326
  Citations

• Resistance to β-adrenoceptor stimulants (a possible explanation for the rise in asthma deaths)

  M. E. Conolly;D. S. Davies;C. T. Dollery;C. F. George

  268
  Citations

• Mechanisms of cell death

  Duncan J. Fawthrop;Alan R. Boobis;Donald S. Davies

  245
  Citations

• Investigations into the mechanism by which sulfated polysaccharides inhibit HIV infection in vitro.

  Myra O. McCLURE;John P. Moore;Dominique F. Blanc;Paul Scotting

  232
  Citations

• Monooxygenase activity of human liver in microsomal fractions of needle biopsy specimens.

  AR Boobis;MJ Brodie;GC Kahn;Fletcher

  219
  Citations

• Metabolism of isoprenaline in dog and man

  M. E. Conolly;D. S. Davies;C. T. Dollery;C. D. Morgan

  200
  Citations

• Development of a comprehensive panel of antibodies against the major xenobiotic metabolising forms of cytochrome P450 in humans

  Robert J Edwards;Delyth A Adams;Patricia S Watts;Donald S Davies

  198
  Citations

• Clonidine withdrawal in hypertension. Changes in blood-pressure and plasma and urinary noradrenaline.

  J.L. Reid;H.J. Dargie;D.S. Davies;L.M.H. Wing

  193
  Citations

• Contribution of CYP1A1 and CYP1A2 to the activation of heterocyclic amines in monkeys and human

  Robert J. Edwards;Bernard P. Murray;Stephen Murray;Thomas Schulz

  177
  Citations

• Intra- and Interindividual Variability in Systemic Exposure in Humans to 2-Amino-3,8-dimethylimidazo[4,5-f]quinoxaline and 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, Carcinogens Present in Cooked Beef

  Anthony M. Lynch;Mark G. Knize;Alan R. Boobis;Nigel J. Gooderham

  175
  Citations

• The specificity of inhibition of debrisoquine 4-hydroxylase activity by quinidine and quinine in the rat is the inverse of that in man.

  Shinichi Kobayashi;Stephen Murray;David Watson;Dorothea Sesardic

  173
  Citations

• Species variation in the response of the cytochrome P-450-dependent monooxygenase system to inducers and inhibitors

  A. R. Boobis;D. Sesardic;B. P. Murray;R. J. Edwards

  157
  Citations

• Distribution and induction of CYP3A1 and CYP3A2 in rat liver and extrahepatic tissues.

  Khadija Debri;Alan R. Boobis;Donald S. Davies;Robert J. Edwards

  143
  Citations

• Human cytochromes P-450

  A. R. Boobis;D. S. Davies

  142
  Citations