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Domitilla Del Vecchio

Domitilla Del Vecchio

D-Index & Metrics

Engineering and Technology

D-Index
41
Citations
7004
World Ranking
6950
National Ranking
1893

Overview

Domitilla Del Vecchio is a researcher affiliated with MIT in the United States. Their work primarily focuses on biochemistry, genetics, and molecular biology, with a strong emphasis on molecular biology as a subfield. The scientific contributions encompass topics related to gene regulatory network analysis, CRISPR and genetic engineering, microbial metabolic engineering and bioproduction, epigenetics and DNA methylation, genomics and chromatin dynamics, bacterial genetics and biotechnology, and pluripotent stem cells research.

Recent publications by Del Vecchio include the following papers:

  • "An endoribonuclease-based feedforward controller for decoupling resource-limited genetic modules in mammalian cells," 2020, Nature Communications
  • "Context-aware synthetic biology by controller design: Engineering the mammalian cell," 2021, Cell Systems
  • "dCas9 regulator to neutralize competition in CRISPRi circuits," 2021, Nature Communications
  • "Design of genetic circuits that are robust to resource competition," 2021, Current Opinion in Systems Biology
  • "Epigenetic cell memory: The gene's inner chromatin modification circuit," 2022, PLoS Computational Biology

Del Vecchio has frequently collaborated with several scientists, including:

  • Simone Bruno
  • Ron Weiss
  • Yili Qian
  • Katherine Ilia
  • Hsin-Ho Huang

The researcher's work is often published in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • arXiv (Cornell University)
  • Nature Communications
  • 2022 IEEE 61st Conference on Decision and Control (CDC)
  • PLoS Computational Biology

The disciplinary concentration of Del Vecchio's research is largely in the biological sciences, with 130 publications classified under biochemistry, genetics, and molecular biology. This research extends deeply into molecular biology, which accounts for 117 publications, followed by genetics. Considerable work also spans biomedical engineering, computational theory and mathematics, and artificial intelligence, reflecting a multidisciplinary approach.

Best Publications

  • Modular cell biology: retroactivity and insulation.

    Domitilla Del Vecchio;Alexander J Ninfa;Eduardo D Sontag

  • Cooperative Collision Avoidance at Intersections: Algorithms and Experiments

    Michael R. Hafner;Drew Cunningham;Lorenzo Caminiti;Domitilla Del Vecchio

  • Resource Competition Shapes the Response of Genetic Circuits.

    Yili Qian;Hsin-Ho Huang;José I. Jiménez;José I. Jiménez;Domitilla Del Vecchio

  • Control theory meets synthetic biology.

    Domitilla Del Vecchio;Aaron J. Dy;Aaron J. Dy;Yili Qian

  • Isocost Lines Describe the Cellular Economy of Genetic Circuits.

    Andras Gyorgy;José I. Jiménez;José I. Jiménez;John Yazbek;Hsin Ho Huang

  • Biomolecular Feedback Systems

    Domitilla Del Vecchio;Richard M. Murray

  • Duckietown: An open, inexpensive and flexible platform for autonomy education and research

    Liam Paull;Jacopo Tani;Heejin Ahn;Javier Alonso-Mora

  • Decomposition of human motion into dynamics-based primitives with application to drawing tasks

    Domitilla Del Vecchio;Richard M. Murray;Pietro Perona

  • Retroactivity controls the temporal dynamics of gene transcription.

    Shridhar Jayanthi;Shridhar Jayanthi;Kayzad Soli Nilgiriwala;Domitilla Del Vecchio

  • A load driver device for engineering modularity in biological networks

    Deepak Mishra;Phillip M Rivera;Allen Lin;Domitilla Del Vecchio

  • Efficient algorithms for collision avoidance at intersections

    Alessandro Colombo;Domitilla Del Vecchio

  • Least Restrictive Supervisors for Intersection Collision Avoidance: A Scheduling Approach

    Alessandro Colombo;Domitilla Del Vecchio

  • Biophysical Constraints Arising from Compositional Context in Synthetic Gene Networks.

    Enoch Yeung;Aaron J. Dy;Aaron J. Dy;Kyle B. Martin;Andrew H. Ng

  • Modularity, context-dependence, and insulation in engineered biological circuits

    Domitilla Del Vecchio

  • A quasi-integral controller for adaptation of genetic modules to variable ribosome demand

    Hsin-Ho Huang;Yili Qian;Domitilla Del Vecchio

  • Realizing 'integral control' in living cells: how to overcome leaky integration due to dilution?

    Yili Qian;Domitilla Del Vecchio

  • An endoribonuclease-based feedforward controller for decoupling resource-limited genetic modules in mammalian cells.

    Ross D. Jones;Yili Qian;Velia Siciliano;Breanna DiAndreth

  • Signaling properties of a covalent modification cycle are altered by a downstream target.

    Alejandra C. Ventura;Peng Jiang;Lauren Van Wassenhove;Domitilla Del Vecchio

  • Development of a Scaled Vehicle With Longitudinal Dynamics of an HMMWV for an ITS Testbed

    R. Verma;D. Del Vecchio;H.K. Fathy

  • Load-Induced Modulation of Signal Transduction Networks

    Peng Jiang;Alejandra C. Ventura;Eduardo D. Sontag;Sofia D. Merajver

  • Isocost Lines Describe the Cellular Economy of Genetic Circuits

    John Yazbek;Hsin-Ho Huang;Hattie Chung;Ron Weiss

  • A load driver device for engineering modularity in biological networks

    Deepak Mishra;Allen Lin;Domitilla Del Vecchio;Ron Weiss

Frequent Co-Authors

Richard M. Murray
Richard M. Murray California Institute of Technology
Eduardo D. Sontag
Eduardo D. Sontag Northeastern University
Sofia D. Merajver
Sofia D. Merajver University of Michigan–Ann Arbor
Alexander J. Ninfa
Alexander J. Ninfa University of Michigan–Ann Arbor
Riccardo Marino
Riccardo Marino University of Rome Tor Vergata
Patrizio Tomei
Patrizio Tomei University of Rome Tor Vergata
Pietro Perona
Pietro Perona California Institute of Technology
Pamela A. Silver
Pamela A. Silver Harvard University

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