World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
70
Citations
25339
World Ranking
6870
National Ranking
173

Overview

David L. Topping is affiliated with the Commonwealth Scientific and Industrial Research Organisation in Australia. Their research spans multiple areas within biochemistry, genetics, molecular biology, and environmental science, focusing notably on health, toxicology, mutagenesis, and physiology.

Their recent publications cover topics related to gut microbiota, respiratory diseases, and environmental toxicology. Notable papers include "Maternal carriage of Prevotella during pregnancy associates with protection against food allergy in the offspring" published in 2020 in Nature Communications, and "Oxidative stress generated DNA damage by 6PPD and other tyre additives in A549 human lung epithelial cells" published in 2025 in Scientific Reports.

The scientist's work is situated in fields such as

  • Biochemistry, Genetics and Molecular Biology
  • Environmental Science

Their subfields of study explore

  • Health, Toxicology and Mutagenesis
  • Molecular Biology
  • General Health Professions
  • Physiology
  • Cancer Research

Key research topics covered in their work include

  • Gut microbiota and health
  • Indigenous Studies and Ecology
  • Asthma and respiratory diseases
  • Indoor Air Quality and Microbial Exposure
  • Carcinogens and Genotoxicity Assessment
  • Toxic Organic Pollutants Impact

David L. Topping has frequently published in venues such as

  • Nature Communications
  • Scientific Reports

Their collaborative network includes frequent co-authorship with

  • Peter Vuillermin
  • Martin O'Hely
  • Fiona Collier
  • Katrina J. Allen
  • Mimi L.K. Tang

Best Publications

  • Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

    Yukihiro Furusawa;Yuuki Obata;Shinji Fukuda;Takaho A. Endo

  • Short-Chain Fatty Acids and Human Colonic Function: Roles of Resistant Starch and Nonstarch Polysaccharides

    David L. Topping;Peter M. Clifton

  • Bifidobacteria can protect from enteropathogenic infection through production of acetate

    Shinji Fukuda;Hidehiro Toh;Koji Hase;Kenshiro Oshima

  • Gut microbial metabolites limit the frequency of autoimmune T cells and protect against type 1 diabetes

    Eliana Mariño;James L Richards;Keiran H McLeod;Dragana Stanley

  • High-amylose wheat generated by RNA interference improves indices of large-bowel health in rats

    Ahmed Regina;Anthony Bird;David Topping;Sarah Bowden

  • The adaptive effects of dietary fish and safflower oil on lipid and lipoprotein metabolism in perfused rat liver

    S H Wong;P J Nestel;R P Trimble;G B Storer

  • Resistant starch as a prebiotic and synbiotic: state of the art.

    David L. Topping;Michihiro Fukushima;Anthony R. Bird

  • Cereal complex carbohydrates and their contribution to human health

    David Topping

  • A review of the potential mechanisms for the lowering of colorectal oncogenesis by butyrate.

    Kim Y. C. Fung;Leah Cosgrove;Trevor Lockett;Richard Head

  • Starches, resistant starches, the gut microflora and human health.

    Anthony R Bird;Ian L Brown;David L Topping

  • Over-expression of specific HvCslF cellulose synthase-like genes in transgenic barley increases the levels of cell wall (1,3;1,4)-β-d-glucans and alters their fine structure.

    Rachel A. Burton;Helen M. Collins;Natalie A. J. Kibble;Jessica A. Smith

  • Fecal Butyrate Levels Vary Widely among Individuals but Are Usually Increased by a Diet High in Resistant Starch

    Alexandra L. McOrist;Rosalind B. Miller;Anthony R. Bird;Jennifer B. Keogh

  • Resistant starch, large bowel fermentation and a broader perspective of prebiotics and probiotics

    A R Bird;M A Conlon;C T Christophersen;D L Topping

  • Variability in Fine Structures of Noncellulosic Cell Wall Polysaccharides from Cereal Grains: Potential Importance in Human Health and Nutrition

    Helen M. Collins;Rachel A. Burton;David L. Topping;Ming-Long Liao

  • Hypocholesterolaemic effects of dietary propionate: studies in whole animals and perfused rat liver.

    Richard J. Illman;David L. Topping;Graeme H. Mclntosh;Rodney P. Trimble

  • Fecal Numbers of Bifidobacteria Are Higher in Pigs Fed Bifidobacterium longum with a High Amylose Cornstarch Than with a Low Amylose Cornstarch

    Ian Brown;Michelle Warhurst;Jayashree Arcot;Martin Playne

  • Acetylated, Propionylated or Butyrylated Starches Raise Large Bowel Short-Chain Fatty Acids Preferentially When Fed to Rats

    Geoffrey Annison;Richard J. Illman;David L. Topping

  • The effects of dietary fish oil on hepatic high density and low density lipoprotein receptor activities in the rat.

    Paul D. Roach;Ambrosios M. Kambouris;Rodney P. Trimble;David L. Topping

  • Two high-amylose maize starches with different amounts of resistant starch vary in their effects on fermentation, tissue and digesta mass accretion, and bacterial populations in the large bowel of pigs

    Anthony R. Bird;Michelle Vuaran;Ian L. Brown;David L. Topping

  • Smoking and health.

    D Topping

Frequent Co-Authors

Anthony R. Bird
Anthony R. Bird Commonwealth Scientific and Industrial Research Organisation
Matthew K. Morell
Matthew K. Morell Commonwealth Scientific and Industrial Research Organisation
Manny Noakes
Manny Noakes Commonwealth Scientific and Industrial Research Organisation
Graeme P. Young
Graeme P. Young Flinders University
Michael Fenech
Michael Fenech University of South Australia
Christopher S. McSweeney
Christopher S. McSweeney Commonwealth Scientific and Industrial Research Organisation
Ying Hu
Ying Hu National Institutes of Health
Michael J. Gidley
Michael J. Gidley University of Queensland
Jun Kikuchi
Jun Kikuchi Yokohama City University
Paul J. Nestel
Paul J. Nestel Baker IDI Heart and Diabetes Institute

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