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Christopher Exley

Christopher Exley

D-Index & Metrics

Chemistry

D-Index
62
Citations
12227
World Ranking
8931
National Ranking
496

Overview

Christopher Exley is affiliated with Keele University in the United Kingdom. Their research primarily focuses on the fields of Agricultural and Biological Sciences and Medicine, with a particular emphasis on Plant Science, Physiology, Nutrition and Dietetics, Molecular Biology, and Health, Toxicology and Mutagenesis.

The scientist's major research topics include:

  • Aluminum toxicity and tolerance in plants and animals
  • Alzheimer's disease research and treatments
  • Trace Elements in Health
  • Heavy Metal Exposure and Toxicity
  • Sphingolipid Metabolism and Signaling
  • Silicon Effects in Agriculture
  • Geochemistry and Elemental Analysis

Christopher Exley has contributed to several peer-reviewed publications. Selected recent papers include:

  • "Aluminium in human brain tissue from donors without neurodegenerative disease: A comparison with Alzheimer's disease, multiple sclerosis and autism," 2020, Scientific Reports
  • "Aluminum and Amyloid-β in Familial Alzheimer's Disease," 2020, Journal of Alzheimer s Disease
  • "CERTL reduces C16 ceramide, amyloid-β levels, and inflammation in a model of Alzheimer's disease," 2021, Alzheimer s Research & Therapy
  • "How is silicic acid transported in plants?," 2020, Silicon
  • "Visualising Silicon in Plants: Histochemistry, Silica Sculptures and Elemental Imaging," 2020, Cells

The scientist frequently publishes in the following venues:

  • Journal of Trace Elements in Medicine and Biology
  • Scientific Reports
  • Journal of Alzheimer s Disease
  • Research Square (Research Square)
  • Faculty of 1000 Research Ltd

Frequent collaborators include:

  • Matthew Mold
  • Emma Shardlow
  • Caroline Linhart
  • Simone M. Crivelli
  • Qian Luo

Best Publications

  • The pro-oxidant activity of aluminum

    Christopher Exley

  • Human exposure to aluminium

    Christopher Exley

  • Aluminium, iron, zinc and copper influence the in vitro formation of amyloid fibrils of Abeta42 in a manner which may have consequences for metal chelation therapy in Alzheimer's disease.

    Emily House;Joanna Collingwood;Ayesha Khan;Olga Korchazkina

  • Acute toxicity of aluminium to fish eliminated in silicon-rich acid waters

    J. D. Birchall;C. Exley;J. S. Chappell;M. J. Phillips

  • A molecular mechanism of aluminium-induced Alzheimer's disease?

    Christopher Exley

  • Aluminium in brain tissue in familial Alzheimer’s disease

    Ambreen Mirza;Andrew King;Claire Troakes;Christopher Exley

  • Silicon in life : A bioinorganic solution to bioorganic essentiality

    Christopher Exley

  • The cellular toxicity of aluminium

    Christopher Exley;J. Derek Birchall

  • A mechanism for acute aluminium toxicity in fish.

    C. Exley;J.S. Chappell;J.D. Birchall

  • The toxicity of aluminium in humans.

    Exley C

  • Speciation of aluminum in biological systems.

    W. R. Harris;G. Berthon;J. P. Day;C. Exley

  • Aluminium in the human brain

    Christopher Exley;Emily R. House

  • A biogeochemical cycle for aluminium

    Christopher Exley

  • Aluminium in brain tissue in autism

    Matthew Mold;Dorcas Umar;Andrew King;Christopher Exley

  • Severe cerebral congophilic angiopathy coincident with increased brain aluminium in a resident of Camelford, Cornwall, UK

    C Exley;M M Esiri

  • Darwin, natural selection and the biological essentiality of aluminium and silicon

    Christopher Exley

  • Ferrous iron formation following the co-aggregation of ferric iron and the Alzheimer's disease peptide β-amyloid (1–42)

    J. Everett;E. Céspedes;L. R. Shelford;C. Exley

  • Aluminium, iron and copper in human brain tissues donated to the Medical Research Council's Cognitive Function and Ageing Study.

    Emily House;Margaret Esiri;Gill Forster;Paul G Ince

  • An interaction of β-amyloid with aluminium in vitro

    Christopher Exley;Nicholas C. Price;Sharon M. Kelly;J.Derek Birchall

  • Aluminium and iron, but neither copper nor zinc, are key to the precipitation of beta-sheets of Abeta_{42} in senile plaque cores in Alzheimer's disease.

    Christopher Exley

  • The biological chemistry of the elements: by J. J. R. Fraústo da Silva and R. J. P. Williams, Oxford University Press, 1991. (xxi + 561 pages) ISBN 0 19 855598 9

    Christopher Exley

Frequent Co-Authors

Romain K. Gherardi
Romain K. Gherardi Paris-Est Créteil University
Gea Guerriero
Gea Guerriero Luxembourg Institute of Science and Technology
Alison E. Ashcroft
Alison E. Ashcroft University of Leeds
Paul E. Fraser
Paul E. Fraser University of Toronto
Bruno Giros
Bruno Giros McGill University
Margaret M. Esiri
Margaret M. Esiri University of Oxford
Antonio Fernández
Antonio Fernández University of Las Palmas de Gran Canaria
Athene M. Donald
Athene M. Donald University of Cambridge
Elke Arenholz
Elke Arenholz Lawrence Berkeley National Laboratory
Olivier Tillement
Olivier Tillement Claude Bernard University Lyon 1

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