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Biology and Biochemistry

D-Index
65
Citations
12710
World Ranking
9321
National Ranking
714

Overview

Christine J. Watson is affiliated with the University of Cambridge in the United Kingdom. Their research spans multiple areas within biochemistry, genetics, molecular biology, medicine, and immunology.

The main fields of study for Watson include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine
  • Immunology and Microbiology

Their subfields of study highlight specialized focus areas such as:

  • Molecular Biology
  • Oncology
  • Immunology
  • Genetics
  • Epidemiology

The primary topics covered in their body of work include:

  • Cancer Cells and Metastasis
  • Immunotherapy and Immune Responses
  • Cell death mechanisms and regulation
  • Animal Genetics and Reproduction
  • Epigenetics and DNA Methylation
  • Wnt/β-catenin signaling in development and cancer
  • Cancer Risks and Factors

Watson has published several papers across various journals, with key recent publications consisting of:

  • "Mammary development in the embryo and adult: new insights into the journey of morphogenesis and commitment" (2020, Development)
  • "Gpr125 is a unifying hallmark of multiple mammary progenitors coupled to tumor latency" (2022, Nature Communications)
  • "The immune environment of the mammary gland fluctuates during post-lactational regression and correlates with tumour growth rate" (2022, Development)
  • "Alveolar cells in the mammary gland: lineage commitment and cell death" (2022, Biochemical Journal)
  • "How should we define mammary stem cells?" (2021, Trends in Cell Biology)

The frequent co-authors that appear in Watson's publications include:

  • Bethan Lloyd-Lewis
  • Walid T. Khaled
  • Elena Spina
  • Julia Simundza
  • Angela Incassati

Watson has contributed to various publication venues, most notably:

  • FEBS Journal
  • Development
  • Nature Communications
  • Biochemical Journal
  • Trends in Cell Biology

Best Publications

  • Suppression of epithelial apoptosis and delayed mammary gland involution in mice with a conditional knockout of Stat3

    Rachel S. Chapman;Paula C. Lourenco;Elizabeth Tonner;David J. Flint

  • Mammary development in the embryo and adult: a journey of morphogenesis and commitment.

    Christine J. Watson;Walid T. Khaled

  • Critical research gaps and translational priorities for the successful prevention and treatment of breast cancer.

    Suzanne A. Eccles;Eric O. Aboagye;Simak Ali;Annie S. Anderson

  • Gene expression profiling of mammary gland development reveals putative roles for death receptors and immune mediators in post-lactational regression

    Richard W E Clarkson;Matthew T Wayland;Jennifer Lee;Tom Freeman

  • Phenotypic and functional characterisation of the luminal cell hierarchy of the mammary gland

    Mona Shehata;Andrew Teschendorff;Gemma Sharp;Nikola Novcic

  • Stat3 controls lysosomal-mediated cell death in vivo

    Peter A. Kreuzaler;Anna D. Staniszewska;Wenjing Li;Nader Omidvar

  • Elevated levels of members of the STAT family of transcription factors in breast carcinoma nuclear extracts.

    CJ Watson;WR Miller

  • Collagen-hyaluronic acid scaffolds for adipose tissue engineering.

    Natalia Davidenko;Jonathan James Campbell;ES Thian;ES Thian;Christine Jannette Watson

  • A STAT3-mediated metabolic switch is involved in tumour transformation and STAT3 addiction

    Marco Demaria;Marco Demaria;Carlotta Giorgi;Magdalena Lebiedzinska;Giovanna Esposito

  • Key stages in mammary gland development - Involution: apoptosis and tissue remodelling that convert the mammary gland from milk factory to a quiescent organ

    Christine J Watson

  • A dual, non-redundant, role for LIF as a regulator of development and STAT3-mediated cell death in mammary gland

    Ekaterini A. Kritikou;Andrew Sharkey;Kathrine Abell;Paul J. Came

  • Killing a cancer: what are the alternatives?

    Peter Kreuzaler;Christine J. Watson

  • STAT3 the oncogene – still eluding therapy?

    Matthew S Wake;Christine Jannette Watson

  • IL-6 acts on endothelial cells to preferentially increase their adherence for lymphocytes.

    C. Watson;S. Whittaker;N. Smith;A. J. Vora

  • Stat5 as a Target for Regulation by Extracellular Matrix

    C. H. Streuli;G. M. Edwards;M. Delcommenne;C. B A Whitelaw

  • Mammary-specific deletion of parathyroid hormone–related protein preserves bone mass during lactation

    Joshua N. VanHouten;Pamela Dann;Andrew F. Stewart;Christine J. Watson

  • Constitutively active Stat3 enhances neu-mediated migration and metastasis in mammary tumors via upregulation of Cten.

    Isaia Barbieri;Sara Pensa;Tania Pannellini;Elena Quaglino

  • The Genes Induced by Signal Transducer and Activators of Transcription (STAT)3 and STAT5 in Mammary Epithelial Cells Define the Roles of these STATs in Mammary Development

    Richard W. E. Clarkson;Marion P. Boland;Ekaterini A. Kritikou;Jennifer M. Lee

  • Remodeling mechanisms of the mammary gland during involution

    Christine J. Watson;Peter A. Kreuzaler

  • Stat3 controls cell death during mammary gland involution by regulating uptake of milk fat globules and lysosomal membrane permeabilization

    Timothy J Sargeant;Bethan Lloyd-Lewis;Henrike K Resemann;Antonio Ramos-Montoya

Frequent Co-Authors

Ruth E. Cameron
Ruth E. Cameron University of Cambridge
Ian Paterson
Ian Paterson University of Cambridge
Valeria Poli
Valeria Poli University of Turin
Alan Richard Clarke
Alan Richard Clarke Cardiff University
Marco Demaria
Marco Demaria University Medical Center Groningen
Charles H. Streuli
Charles H. Streuli University of Manchester
Matthew John Smalley
Matthew John Smalley Cardiff University
Jane E. Visvader
Jane E. Visvader Walter and Eliza Hall Institute of Medical Research
Paolo Provero
Paolo Provero University of Turin
Geoffrey J. Lindeman
Geoffrey J. Lindeman Peter MacCallum Cancer Centre

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