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D-Index & Metrics

Biology and Biochemistry

D-Index
46
Citations
13459
World Ranking
18834
National Ranking
73

Overview

Alan G. Porter is affiliated with the National University of Singapore in Singapore. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, as well as Medicine. The subfields covered include Molecular Biology and Hematology.

The scientist's work focuses on several main topics, including:

  • Protein Degradation and Inhibitors
  • Multiple Myeloma Research and Treatments
  • Ubiquitin and proteasome pathways

Porter has contributed to the literature with recent publications such as:

  • PCMT1 generates the C-terminal cyclic imide degron on CRBN substrates, published in 2025 in bioRxiv (Cold Spring Harbor Laboratory)

Frequent collaborators in their research include:

  • Zhenguang Zhao
  • Wenqing Xu
  • Ethan Yang Feng
  • Shiyun Cao
  • Alba Hermoso-López

The major venue where Porter's work has appeared is bioRxiv (Cold Spring Harbor Laboratory).

Best Publications

  • Specific cleavage of the retinoblastoma protein by an ICE-like protease in apoptosis.

    R. U. Janicke;P. A. Walker;Xiao Yu Lin;A. G. Porter

  • Caspase-8/FLICE functions as an executioner caspase in anticancer drug-induced apoptosis.

    Ingo H Engels;Ania Stepczynska;Christopher Stroh;Kirsten Lauber

  • Reoxygenation-specific activation of the antioxidant transcription factor Nrf2 mediates cytoprotective gene expression in ischemia-reperfusion injury

    Martin O. Leonard;Niamh E. Kieran;Katherine Howell;Melissa J. Burne

  • The downstream box: an efficient and independent translation initiation signal in Escherichia coli

    M L Sprengart;E Fuchs;A G Porter

  • Expression Analysis of the Human Caspase-1 Subfamily Reveals Specific Regulation of the CASP5 Gene by Lipopolysaccharide and Interferon-γ

    Xiao Yu Lin;Michael Shui Kuen Choi;Alan G. Porter

  • Nitric Oxide-induced Transcriptional Up-regulation of Protective Genes by Nrf2 via the Antioxidant Response Element Counteracts Apoptosis of Neuroblastoma Cells

    Saravanakumar Dhakshinamoorthy;Alan G. Porter

  • NF-κB Activation Mediates Doxorubicin-induced Cell Death in N-type Neuroblastoma Cells

    Xin Bian;Linda M. McAllister-Lucas;Feng Shao;Kurt R. Schumacher

  • AIF suppresses chemical stress-induced apoptosis and maintains the transformed state of tumor cells

    Alexander Urbano;Umayal Lakshmanan;Poh Heok Choo;Jair Chau Kwan

  • Protein translocation in apoptosis

    Alan G. Porter

  • Ionizing radiation but not anticancer drugs causes cell cycle arrest and failure to activate the mitochondrial death pathway in MCF-7 breast carcinoma cells.

    Reiner U Jänicke;Ingo H Engels;Torsten Dunkern;Bernd Kaina

  • JNK-dependent phosphorylation of c-Jun on serine 63 mediates nitric oxide-induced apoptosis of neuroblastoma cells

    Lei Li;Zhiwei Feng;Alan G. Porter

  • Purification and characterization of human brain prolyl endopeptidase.

    Singh Kalwant;A. G. Porter

  • Site-directed mutagenesis suggests close functional relationship between a human rhinovirus 3C cysteine protease and cellular trypsin-like serine proteases.

    K.-C. Cheah;L. E.-C. Leong;A. G. Porter

  • Does apoptosis-inducing factor (AIF) have both life and death functions in cells?

    Alan G. Porter;Alexander G.L. Urbano

  • Caspase-4 Interacts with TNF Receptor-Associated Factor 6 and Mediates Lipopolysaccharide-Induced NF-κB-Dependent Production of IL-8 and CC Chemokine Ligand 4 (Macrophage-Inflammatory Protein-1β)

    Umayal Lakshmanan;Alan G. Porter

  • Neuronal differentiation and protection from nitric oxide-induced apoptosis require c-Jun-dependent expression of NCAM140.

    Zhiwei Feng;Lei Li;Poh Yong Ng;Alan G. Porter

  • Structural and functional domains in human tumour necrosis factors.

    Cynthia R. Goh;Alan G. Porter

  • Unusual Amino Acid Determinants of Host Range in the Mtx2 Family of Mosquitocidal Toxins

    Siew Wee Chan;Thirumaran Thanabalu;Boon Yu Wee;Alan G. Porter

  • Topoisomerase inhibitor camptothecin sensitizes mouse hepatocytes in vitro and in vivo to TNF‐mediated apoptosis

    Hannes Hentze;Hannes Hentze;Markus Latta;Gerald Künstle;Saravanakumar Dhakshinamoorthy

  • Flipping the safety catch of procaspase-3.

    Alan G Porter

Frequent Co-Authors

Klaus Schulze-Osthoff
Klaus Schulze-Osthoff University of Tübingen
Feng Shao
Feng Shao Chinese Academy of Sciences
Cliona O'Farrelly
Cliona O'Farrelly Trinity College Dublin
Keiichi I. Nakayama
Keiichi I. Nakayama Institute of Science Tokyo
Cormac T. Taylor
Cormac T. Taylor University College Dublin
Harald Wajant
Harald Wajant University of Würzburg
Sebastian Wesselborg
Sebastian Wesselborg University of Tübingen
Kirsten Lauber
Kirsten Lauber Ludwig-Maximilians-Universität München
Albrecht Wendel
Albrecht Wendel University of Konstanz
Hamid Rabb
Hamid Rabb Johns Hopkins University

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