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Wentzel C. A. Gelderblom

Wentzel C. A. Gelderblom

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Biology and Biochemistry
South Africa
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
68
Citations
19331
World Ranking
7703
National Ranking
11

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in South Africa Leader Award
  • 2022 - Research.com Biology and Biochemistry in South Africa Leader Award

Overview

Wentzel C. A. Gelderblom was affiliated with Stellenbosch University in South Africa and had a research focus spanning medicine, agricultural and biological sciences, and biochemistry, genetics, and molecular biology. Their work contributed to several subfields including plant science, pathology and forensic medicine, biochemistry, molecular biology, and cancer research.

The primary research topics pursued by Gelderblom included mycotoxins in agriculture and food, phytochemicals and antioxidant activities, carcinogens and genotoxicity assessment, plant pathogens and fungal diseases, tea polyphenols and their effects, tannin and tannase with anticancer activities, and glutathione transferases and polymorphisms.

Gelderblom's scholarly output featured multiple publications in scientific journals. Notable papers included:

  • "Enzymatic detoxification of the fumonisin mycotoxins during dry milling of maize" (2020) in Food Control
  • "Differential Cytotoxicity of Rooibos and Green Tea Extracts against Primary Rat Hepatocytes and Human Liver and Colon Cancer Cells - Causal Role of Major Flavonoids" (2020) in Nutrition and Cancer
  • "Fumonisin B1 protects against long-chained polyunsaturated fatty acid-induced cell death in HepG2 cells - implications for cancer promotion" (2024) in Biochimica et Biophysica Acta (BBA) - Biomembranes
  • "Biocontrol of Fusarium Species Utilizing Indigenous Rooibos and Honeybush Extracts" (2023) in Microbiology Spectrum
  • "Autophagy-induced cell death by aqueous and polyphenol-enriched extracts of honeybush (Cyclopia spp.) in liver and colon cancer cells" (2024) in Food Science & Nutrition

The scientist collaborated frequently with a number of co-authors, including Hester-Mari Burger, Sedicka Samodien, Maryna de Kock, Elizabeth Joubert, and Sonja Swanevelder, each with two joint publications.

Gelderblom's research appeared regularly in respected journals such as Food Control, Nutrition and Cancer, Biochimica et Biophysica Acta (BBA) - Biomembranes, Microbiology Spectrum, and Food Science & Nutrition.

Best Publications

  • Fumonisins--novel mycotoxins with cancer-promoting activity produced by Fusarium moniliforme.

    W. C. A. Gelderblom;K. Jaskiewicz;W. F. O. Marasas;P. G. Thiel

  • IARC Monographs on the evaluation of carcinogenic risks to humans: Some traditional herbal medicines, some mycotoxins, naphthalene and styrene

    Ahti Anttila;Ramesh V. Bhat;James A. Bond;Susan J. Borghoff

  • Leukoencephalomalacia in a horse induced by fumonisin B1 isolated from Fusarium moniliforme.

    Wfo Marasas;TS Kellerman;Wentzel Ca Gelderblom;Jaw Coetzer

  • Toxicity and carcinogenicity of the fusanum monilzforine metabolite, fumonisin B1, in rats.

    Wentzel Ca Gelderblom;Npj Kriek;Wfo Marasas;PG Thiel

  • Structure elucidation of the fumonisins, mycotoxins from Fusarium moniliforme

    S. Catherine Bezuidenhout;Wentzel C. A. Gelderblom;Charles P. Gorst-Allman;R. Marthinus Horak

  • Fumonisins Disrupt Sphingolipid Metabolism, Folate Transport, and Neural Tube Development in Embryo Culture and In Vivo: A Potential Risk Factor for Human Neural Tube Defects among Populations Consuming Fumonisin-Contaminated Maize

    Walter F O Marasas;Ronald T. Riley;Katherine A. Hendricks;Victoria L. Stevens

  • Leukoencephalomalacia in two horses induced by oral dosing of fumonisin B1.

    T. S. Kellerman;W. F. O. Marasas;P. G. Thiel;W. C. A. Gelderblom

  • Quantitative Determination of Fumonisins B1 and B2 by High-Performance Liquid Chromatography with Fluorescence Detection

    G. S. Shephard;E. W. Sydenham;P. G. Thiel;W. C. A. Gelderblom

  • South African herbal teas: Aspalathus linearis, Cyclopia spp. and Athrixia phylicoides—A review

    E. Joubert;W. C. A. Gelderblom;W. C. A. Gelderblom;Ann Louw;D. De Beer

  • The implications of naturally occurring levels of fumonisins in corn for human and animal health.

    Pieter G. Thiel;Walter F. O. Marasas;Eric W. Sydenham;Gordon S. Shephard

  • Degradation of aflatoxin B1 by fungal laccase enzymes

    J.F. Alberts;W.C.A. Gelderblom;W.C.A. Gelderblom;A. Botha;W.H. van Zyl

  • Isolation of the fumonisin mycotoxins: A quantitative approach

    Maria E. Cawood;Wentzel C. A. Gelderblom;Robert Vleggaar;Yosef Behrend

  • Survey of fumonisin production by Fusarium species.

    P G Thiel;W F Marasas;E W Sydenham;G S Shephard

  • Evidence for the natural occurrence of fumonisin B1, a mycotoxin produced by Fusarium moniliforme in corn.

    Eric W. Sydenham;Wentzel C. A. Gelderblom;Pieter G. Thiel;Walter F. O. Marasas

  • Antioxidant Activity of South African Red and White Cultivar Wines: Free Radical Scavenging

    Dalene De Beer;Elizabeth Joubert;Wentzel C A Gelderblom;Marena Manley

  • Effects of temperature and incubation period on production of fumonisin B1 by Fusarium moniliforme.

    J. F. Alberts;W. C. A. Gelderblom;P. G. Thiel;W. F. O. Marasas

  • Fumonisins: isolation, chemical characterization and biological effects.

    Wentzel C. A. Gelderblom;Walter F. O. Marasas;R. Vleggaar;Pieter G. Thiel

  • Fumonisin-Induced Hepatocarcinogenesis: Mechanisms Related to Cancer Initiation and Promotion

    Wentzel C. A. Gelderblom;Stefan Abel;Cornelius M. Smuts;Jeanine Marnewick

  • Structure-activity relationships of fumonisins in short-term carcinogenesis and cytotoxicity assays.

    W.C.A. Gelderblom;M.E. Cawood;S.D. Snyman;R. Vleggaar

  • Oxidative damage and fumonisin B1-induced toxicity in primary rat hepatocytes and rat liver in vivo

    S Abel;W.C.A Gelderblom

Frequent Co-Authors

Walter F. O. Marasas
Walter F. O. Marasas Stellenbosch University
Elizabeth Joubert
Elizabeth Joubert Stellenbosch University
Gordon S. Shephard
Gordon S. Shephard Cape Peninsula University of Technology
John P. Rheeder
John P. Rheeder Cape Peninsula University of Technology
Christopher P. Wild
Christopher P. Wild International Agency For Research On Cancer
Ronald T. Riley
Ronald T. Riley Agricultural Research Service
Timothy D. Phillips
Timothy D. Phillips Texas A&M University
J. David Miller
J. David Miller Carleton University
Kenneth A. Voss
Kenneth A. Voss Agricultural Research Service
Sandra Combrinck
Sandra Combrinck Tshwane University of Technology

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