Toshimitsu Uede

Best Publications

• Immunologic Self-Tolerance Maintained by Cd25+Cd4+Regulatory T Cells Constitutively Expressing Cytotoxic T Lymphocyte–Associated Antigen 4

  Takeshi Takahashi;Tomoyuki Tagami;Sayuri Yamazaki;Toshimitsu Uede

  2863
  Citations

• Tumor-infiltrating DCs suppress nucleic acid–mediated innate immune responses through interactions between the receptor TIM-3 and the alarmin HMGB1

  Shigeki Chiba;Muhammad Baghdadi;Hisaya Akiba;Hironori Yoshiyama

  910
  Citations

• Osteopontin deficiency protects joints against destruction in anti-type II collagen antibody-induced arthritis in mice

  Kenji Yumoto;Muneaki Ishijima;Susan R. Rittling;Kunikazu Tsuji

  293
  Citations

• Osteopontin as a Mediator of NKT Cell Function in T Cell-Mediated Liver Diseases

  Hongyan Diao;Shigeyuki Kon;Kazuya Iwabuchi;Chiemi Kimura

  271
  Citations

• Essential role of the cryptic epitope SLAYGLR within osteopontin in a murine model of rheumatoid arthritis.

  Nobuchika Yamamoto;Fumihiko Sakai;Shigeyuki Kon;Junko Morimoto

  257
  Citations

• Osteopontin functionally activates dendritic cells and induces their differentiation toward a Th1-polarizing phenotype.

  Andreas C. Renkl;Julia Wussler;Thomas Ahrens;Käthe Thoma

  239
  Citations

• Interleukin-17A Deficiency Accelerates Unstable Atherosclerotic Plaque Formation in Apolipoprotein E-Deficient Mice

  Keiko Danzaki;Yutaka Matsui;Masahiro Ikesue;Daichi Ohta

  237
  Citations

• Role of osteopontin in the pathogenesis of bleomycin-induced pulmonary fibrosis

  Fumiyuki Takahashi;Kazuhisa Takahashi;Tatsuma Okazaki;Kayo Maeda

  229
  Citations

• Extracellular matrix protein tenascin-C is required in the bone marrow microenvironment primed for hematopoietic regeneration.

  Ayako Nakamura-Ishizu;Yuji Okuno;Yoshiki Omatsu;Keisuke Okabe

  183
  Citations

• Role of the integrin-binding protein osteopontin in lymphatic metastasis of breast cancer.

  Alison L. Allan;Rosamma George;Rosamma George;Sharon A. Vantyghem;Mark W. Lee;Mark W. Lee

  161
  Citations

• Enhanced local production of osteopontin in rheumatoid joints

  Shiro Ohshima;Norihiko Yamaguchi;Katsuhiro Nishioka;Toru Mima

  157
  Citations

• Functions and development of red pulp macrophages.

  Daisuke Kurotaki;Toshimitsu Uede;Tomohiko Tamura

  127
  Citations

• Osteopontin, a coordinator of host defense system : A cytokine or an extracellular adhesive protein?

  Toshimitsu Uede;Yohko Katagiri;Junko Iizuka;Masaaki Murakami

  122
  Citations

• Induction of immunologic tolerance to cardiac allograft by simultaneous blockade of inducible co-stimulator and cytotoxic T-lymphocyte antigen 4 pathway.

  Hisanori Kosuge;Jun-Ichi Suzuki;Ryo Gotoh;Noritaka Koga

  121
  Citations

• Mechanism of macrophage activation by chitin derivatives.

  Takashi Mori;Masaaki Murakami;Masahiro Okumura;Tsuyoshi Kadosawa

  115
  Citations

• Development of autoimmune insulitis is prevented in Eαd but not in Aβk NOD transgenic mice

  Masahiro Uehira;Masashi Uno;Thomas Kürner;Hitoshi Kikutani

  113
  Citations

• Osteopontin; as a target molecule for the treatment of inflammatory diseases.

  Junko Morimoto;Shigeyuki Kon;Yutaka Matsui;Toshimitsu Uede

  112
  Citations

• A CD153+CD4+ T Follicular Cell Population with Cell-Senescence Features Plays a Crucial Role in Lupus Pathogenesis via Osteopontin Production

  Suhail Tahir;Yuji Fukushima;Keiko Sakamoto;Kyosuke Sato

  108
  Citations

• Accelerated development of aging-associated and instability-induced osteoarthritis in osteopontin-deficient mice.

  Yuichiro Matsui;Norimasa Iwasaki;Shigeyuki Kon;Daisuke Takahashi

  108
  Citations

• Mapping of functional epitopes of osteopontin by monoclonal antibodies raised against defined internal sequences

  Shigeyuki Kon;Yasuyuki Yokosaki;Masahiro Maeda;Tatsuya Segawa

  100
  Citations