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Biology and Biochemistry

D-Index
63
Citations
13549
World Ranking
10263
National Ranking
277

Overview

Simon Easteal is affiliated with the Australian National University in Australia and primarily conducts research in the fields of Biochemistry, Genetics, and Molecular Biology, as well as Medicine. Their work spans various subfields including Molecular Biology, Genetics, Public Health, Environmental and Occupational Health, Infectious Diseases, and Physiology.

The scientist's research focuses notably on topics such as Genomics and Rare Diseases, Mitochondrial Function and Pathology, Genomics and Phylogenetic Studies, Molecular Biology Techniques and Applications, Ethics in Clinical Research, Alzheimer's disease research and treatments, and Bioinformatics and Genomic Networks.

Easteal has been involved in several publications with a range of coauthors, frequently collaborating with Azure Hermes, Gareth Baynam, Hardip R. Patel, Devashi Paliwal, and Misty R. Jenkins. The venues where their work appears most often include Nature, bioRxiv (Cold Spring Harbor Laboratory), Frontiers in Pediatrics, The American Journal of Human Genetics, and The Journals of Gerontology Series A.

Notable recent papers authored or co-authored by Simon Easteal include:

  • Indigenous Australian genomes show deep structure and rich novel variation, 2023, Nature
  • Barriers and Considerations for Diagnosing Rare Diseases in Indigenous Populations, 2020, Frontiers in Pediatrics
  • The landscape of genomic structural variation in Indigenous Australians, 2023, Nature
  • Equitable Expanded Carrier Screening Needs Indigenous Clinical and Population Genomic Data, 2020, The American Journal of Human Genetics
  • APOE ε4 and the Influence of Sex, Age, Vascular Risk Factors, and Ethnicity on Cognitive Decline, 2020, The Journals of Gerontology Series A

The scientist's publications often concentrate on genetic diversity in Indigenous Australian populations, structural genomic variation, and the implications of genetics in clinical medicine and public health. Their work on equitable carrier screening highlights the importance of including Indigenous clinical and population genomic data in genetic testing and diagnosis strategies.

Best Publications

  • ACTN3 Genotype Is Associated with Human Elite Athletic Performance

    Nan Yang;Daniel G. MacArthur;Daniel G. MacArthur;Jason P. Gulbin;Allan G. Hahn

  • Identification, characterization, and crystal structure of the Omega class glutathione transferases.

    Philip G. Board;Marjorie Coggan;Gareth Chelvanayagam;Simon Easteal

  • A common nonsense mutation results in alpha-actinin-3 deficiency in the general population.

    Kathryn N. North;Kathryn N. North;Nan Yang;Duangrurdee Wattanasirichaigoon;Michelle Mills

  • Differential expression of the actin-binding proteins, α-actinin-2 and -3, in different species: implications for the evolution of functional redundancy

    Michelle A. Mills;Nan Yang;Ron P. Weinberger;Douglas L. Vander Woude

  • Apolipoprotein E allele ∈4, dementia, and cognitive decline in a population sample

    A.S Henderson;A.F Jorm;A.E Korten;H Christensen

  • Loss of ACTN3 gene function alters mouse muscle metabolism and shows evidence of positive selection in humans.

    Daniel MacArthur;Jane T Seto;Jane T Seto;Joanna M Raftery;Kate G Quinlan;Kate G Quinlan

  • Mitochondrial DNA sequences in ancient Australians: Implications for modern human origins

    Gregory J. Adcock;Elizabeth S. Dennis;Simon Easteal;Gavin A. Huttley

  • Collaborative meta-analysis finds no evidence of a strong interaction between stress and 5-HTTLPR genotype contributing to the development of depression

    R. C. Culverhouse;N. L. Saccone;A. C. Horton;Y. Ma

  • A Population-Based Study of Attention Deficit/Hyperactivity Disorder Symptoms and Associated Impairment in Middle-Aged Adults

    Debjani Das;Nicolas Cherbuin;Peter Butterworth;Kaarin J. Anstey

  • A program for calculating and displaying compatibility matrices as an aid in determining reticulate evolution in molecular sequences

    Ingrid B. Jakobsen;Simon Easteal

  • Cohort Profile: The PATH through life project

    Kaarin Anstey;Helen Christensen;Peter Butterworth;Simon Easteal

  • Memory complaints in a community sample aged 60-64 years: associations with cognitive functioning, psychiatric symptoms, medical conditions, APOE genotype, hippocampus and amygdala volumes, and white-matter hyperintensities.

    Anthony F Jorm;Peter Butterworth;Kaarin J Anstey;Helen M Christensen

  • The history of introductions of Bufo marinus (Amphibia: Anura); a natural experiment in evolution

    Simon Easteal

  • APOE genotype and cognitive functioning in a large age-stratified population sample.

    Anthony F Jorm;Karen A Mather;Peter Butterworth;Kaarin J Anstey

  • Adaptive evolution of the tumour suppressor BRCA1 in humans and chimpanzees. Australian Breast Cancer Family Study.

    Gavin A. Huttley;Simon Easteal;Melissa C. Southey;Andrea Tesoriero

  • An association study of a functional polymorphism of the serotonin transporter gene with personality and psychiatric symptoms

    A F Jorm;A S Henderson;P A Jacomb;H Christensen

  • Corpus callosum size, reaction time speed and variability in mild cognitive disorders and in a normative sample.

    Kaarin J Anstey;Holly A Mack;Helen M Christensen;Shu-Chen Li

  • The selective advantage of attendant ants for the larvae of a lycaenid butterfly, Glaucopsyche lygdamus

    N. E. Pierce;S. Easteal

  • Mind the Gaps: Evidence of Bias in Estimates of Multiple Sequence Alignments

    Tanya Golubchik;Michael J Wise;Simon Easteal;Lars Sommer Jermiin

  • Characterization of the Omega class glutathione transferases

    Philip Board;Marjorie Coggan;Gareth Chelvanayagam;Simon Easteal

Frequent Co-Authors

Kaarin J. Anstey
Kaarin J. Anstey University of New South Wales
Anthony F. Jorm
Anthony F. Jorm University of Melbourne
Perminder S. Sachdev
Perminder S. Sachdev University of New South Wales
Helen Christensen
Helen Christensen University of New South Wales
Mauricio Arcos-Burgos
Mauricio Arcos-Burgos University of Antioquia
Lars S. Jermiin
Lars S. Jermiin Australian National University
Patricia A. Jacomb
Patricia A. Jacomb Australian National University
Andrew Mackinnon
Andrew Mackinnon University of New South Wales
Peter Butterworth
Peter Butterworth Australian National University
Wei Wen
Wei Wen University of New South Wales

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