World's Best Scientists 2026 revealed!

D-Index & Metrics

Molecular Biology

D-Index
56
Citations
9779
World Ranking
2216
National Ranking
1098

Overview

Silvia Santamarina-Fojo is affiliated with the National Institutes of Health in the United States. Their research primarily focuses on the intersection of biochemistry, genetics, and molecular biology, with specific attention to medicine. The scientist's work spans several subfields including genetics and epidemiology.

The main topics covered in their research include diabetes and associated disorders as well as liver disease diagnosis and treatment.

  • Diabetes and associated disorders
  • Liver Disease Diagnosis and Treatment

Silvia Santamarina-Fojo has contributed to publications in recognized venues such as UNC Libraries.

  • UNC Libraries

One recent publication authored in collaboration with Junji Kobayashi is titled "Analysis of Protein Structure-Function in Vivo: ADENOVIRUS-MEDIATED TRANSFER OF LIPASE LID MUTANTS IN HEPATIC LIPASE-DEFICIENT MICE", published in 2021 by UNC Libraries.

  • Analysis of Protein Structure-Function in Vivo: ADENOVIRUS-MEDIATED TRANSFER OF LIPASE LID MUTANTS IN HEPATIC LIPASE-DEFICIENT MICE (2021, UNC Libraries)

The scientist frequently collaborates with colleagues including:

  • Junji Kobayashi
  • Deborah Applebaum-Bowden
  • Klaus A. Dugi
  • David R. Brown
  • Vikram S. Kashyap

The scope of Silvia Santamarina-Fojo's research illustrates an integration of clinical and molecular approaches to better understand metabolic and liver-related diseases. Their work involving protein structure and function analysis in vivo highlights an emphasis on experimental techniques that contribute to biomedical knowledge in hepatic and metabolic disorders.

Best Publications

  • Cellular localization and trafficking of the human ABCA1 transporter.

    Edward B. Neufeld;Alan T. Remaley;Stephen J. Demosky;John A. Stonik

  • Apolipoprotein Specificity for Lipid Efflux by the Human ABCAI Transporter

    Alan T. Remaley;John A. Stonik;Steven J. Demosky;Edward B. Neufeld

  • Human ATP-binding cassette transporter 1 (ABC1): Genomic organization and identification of the genetic defect in the original Tangier disease kindred

    Alan T. Remaley;Stephan Rust;Marie Rosier;Cathy Knapper

  • The role of hepatic lipase in lipoprotein metabolism and atherosclerosis

    Unknown

  • High plasma HDL concentrations associated with enhanced atherosclerosis in transgenic mice overexpressing lecithin-cholesteryl acyltransferase.

    Annie M. Bérard;Bernhard Föger;Alan Remaley;Robert Shamburek

  • Synthetic amphipathic helical peptides promote lipid efflux from cells by an ABCA1-dependent and an ABCA1-independent pathway.

    Alan T. Remaley;Fairwell Thomas;John A. Stonik;Steve J. Demosky

  • The ABCA1 transporter modulates late endocytic trafficking: insights from the correction of the genetic defect in Tangier disease.

    Edward B. Neufeld;John A. Stonik;Stephen J. Demosky;Catherine L. Knapper

  • Complete genomic sequence of the human ABCA1 gene: Analysis of the human and mouse ATP-binding cassette A promoter

    Silvia Santamarina-Fojo;Katherine Peterson;Catherine Knapper;Yang Qiu

  • Regulation and intracellular trafficking of the ABCA1 transporter.

    Silvia Santamarina-Fojo;Alan T. Remaley;Edward B. Neufeld;H. Bryan Brewer

  • The human ABCG1 gene: identification of LXR response elements that modulate expression in macrophages and liver

    Steven L. Sabol;H. Bryan Brewer;Silvia Santamarina-Fojo

  • Plasma Phospholipid Transfer Protein: ADENOVIRUS-MEDIATED OVEREXPRESSION IN MICE LEADS TO DECREASED PLASMA HIGH DENSITY LIPOPROTEIN (HDL) AND ENHANCED HEPATIC UPTAKE OF PHOSPHOLIPIDS AND CHOLESTERYL ESTERS FROM HDL *

    Bernhard Föger;Silvia Santamarina-Fojo;Robert D. Shamburek;Catherine L. Parrot

  • Analysis of Glomerulosclerosis and Atherosclerosis in Lecithin Cholesterol Acyltransferase-deficient Mice

    Gilles Lambert;Naohiko Sakai;Boris L. Vaisman;Edward B. Neufeld

  • Structure, function and role of lipoprotein lipase in lipoprotein metabolism.

    Unknown

  • Hepatic lipase promotes the selective uptake of high density lipoprotein-cholesteryl esters via the scavenger receptor B1.

    Gilles Lambert;Michael B. Chase;Klaus Dugi;Andre Bensadoun

  • Targeted Disruption of the Mouse Lecithin:Cholesterol Acyltransferase (LCAT) Gene: GENERATION OF A NEW ANIMAL MODEL FOR HUMAN LCAT DEFICIENCY

    Sakai N;Vaisman Bl;Koch Ca;Hoyt Rf

  • Effects of FXR in foam-cell formation and atherosclerosis development.

    Grace L. Guo;Silvia Santamarina-Fojo;Taro E. Akiyama;Marcelo J.A. Amar

  • The orphan nuclear receptor LRH-1 activates the ABCG5/ABCG8 intergenic promoter.

    Lita A. Freeman;Arion Kennedy;Justina Wu;Samantha Bark

  • Lecithin-cholesterol acyltransferase: role in lipoprotein metabolism, reverse cholesterol transport and atherosclerosis.

    Silvia Santamarina-Fojo;Gilles Lambert;Jeffrey Hoeg;H. Brewer

  • The ABCA1 transporter functions on the basolateral surface of hepatocytes

    Edward B Neufeld;Steven J Demosky;John A Stonik;Christian Combs

  • ABCA1 overexpression in the liver of LDLr-KO mice leads to accumulation of Pro-atherogenic lipoproteins and enhanced atherosclerosis

    Charles W. Joyce;Elke M. Wagner;Federica Basso;Marcelo J. Amar

Frequent Co-Authors

H. Bryan Brewer
H. Bryan Brewer MedStar Washington Hospital Center
Alan T. Remaley
Alan T. Remaley National Institutes of Health
Beverly Paigen
Beverly Paigen University of Pennsylvania
Santica M. Marcovina
Santica M. Marcovina University of Washington
Nobuyo Maeda
Nobuyo Maeda University of North Carolina at Chapel Hill
Donald S. Fredrickson
Donald S. Fredrickson National Institutes of Health
André Bensadoun
André Bensadoun Cornell University
Daniel J. Rader
Daniel J. Rader University of Pennsylvania
Giovanna Chimini
Giovanna Chimini Grenoble Alpes University
Michael Dean
Michael Dean National Institutes of Health

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Best Scientists Citing Silvia Santamarina-Fojo