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Genetics

D-Index
49
Citations
14900
World Ranking
3973
National Ranking
141

Overview

Rob B. van der Luijt is affiliated with Leiden University Medical Center in the Netherlands. Their research primarily focuses on areas within biochemistry, genetics, and molecular biology, with particular emphasis on genetics and cancer research. Their work also spans molecular biology, public health, environmental and occupational health, and pulmonary and respiratory medicine.

The main topics addressed in their publications include:

  • BRCA gene mutations in cancer
  • Cancer genomics and diagnostics
  • Breast cancer treatment studies
  • Genetic associations and epidemiology
  • Molecular biology techniques and applications
  • Male breast health studies
  • Breast lesions and carcinomas

They have contributed to various scientific venues, frequently publishing in:

  • Cancer Research
  • UNC Libraries
  • The Journal of Pathology Clinical Research
  • PubMed
  • The Journal of Clinical Endocrinology & Metabolism

Frequent co-authors collaborating with Rob B. van der Luijt include:

  • John W.M. Martens
  • Christi J. van Asperen
  • Peter Devilee
  • Anne Vincent-Salomon
  • Irene L. Andrulis

Their recent papers represent a range of studies related to breast cancer genetics and diagnostics:

  • "A high proportion of novel mutations in BRCA1 with strong founder effects among Dutch and Belgian hereditary breast and ovarian cancer families," published in 2020 in PubMed
  • "Inter-observer agreement for the histological diagnosis of invasive lobular breast carcinoma," published in 2021 in The Journal of Pathology Clinical Research
  • "Common Breast Cancer Susceptibility Alleles and the Risk of Breast Cancer for BRCA1 and BRCA2 Mutation Carriers: Implications for Risk Prediction," published in 2020 in UNC Libraries
  • "Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent," published in 2020 in UNC Libraries
  • "Abstract PD9-05: Stromal tumor-infiltrating lymphocytes identify early-stage triple-negative breast cancer patients with favorable outcomes at 10-year follow-up in the absence of systemic therapy: a pooled analysis of 1835 patients," published in 2023 in Cancer Research

Best Publications

  • Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

    Bjarni J. Vilhjálmsson;Jian Yang;Hilary K. Finucane;Alexander Gusev

  • Association analysis identifies 65 new breast cancer risk loci

    Kyriaki Michailidou;Kyriaki Michailidou;Sara Lindström;Sara Lindström;Joe Dennis;Jonathan Beesley

  • Large-scale genotyping identifies 41 new loci associated with breast cancer risk

    Kyriaki Michailidou;Per Hall;Anna Gonzalez-Neira;Maya Ghoussaini

  • Pathology of Breast and Ovarian Cancers among BRCA1 and BRCA2 Mutation Carriers: Results from the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA).

    Nasim Mavaddat;Daniel Barrowdale;Irene L. Andrulis;Susan M. Domchek

  • Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

    Kyriaki Michailidou;Jonathan Beesley;Sara Lindstrom;Sander Canisius

  • Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

    Stig E. Bojesen;Stig E. Bojesen;Karen A. Pooley;Sharon E. Johnatty;Jonathan Beesley

  • MicroRNA related polymorphisms and breast cancer risk

    Sofia Khan;Dario Greco;Dario Greco;Kyriaki Michailidou;Roger L. Milne;Roger L. Milne

  • Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer

    Catherine M Phelan;Karoline B Kuchenbaecker;Karoline B Kuchenbaecker;Jonathan P Tyrer;Siddhartha P Kar

  • The ‘just-right’ signaling model: APC somatic mutations are selected based on a specific level of activation of the β-catenin signaling cascade

    Cristina Albuquerque;Cor Breukel;Rob van der Luijt;Paulo Fidalgo

  • A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population

    Antonis C. Antoniou;Xianshu Wang;Zachary S. Fredericksen;Lesley McGuffog

  • Genetic analysis of von Hippel-Lindau disease.

    Morgan Nordstrom-O'Brien;Rob B. van der Luijt;Ellen van Rooijen;Ans M. van den Ouweland

  • Germline CDKN1B/p27Kip1 mutation in multiple endocrine neoplasia.

    Marianthi Georgitsi;Anniina Raitila;Auli Karhu;Rob B. van der Luijt

  • Rapid Detection of Translation-Terminating Mutations at the Adenomatous Polyposis Coli (APC) Gene by Direct Protein Truncation Test

    Rob van der Luijt;P.Meera Khan;Hans Vasen;Claus van Leeuwen

  • Mutational spectrum in a worldwide study of 29,700 families with BRCA1 or BRCA2 mutations

    Timothy R. Rebbeck;Tara M. Friebel;Eitan Friedman;Ute Hamann

  • Targeted sequencing by proximity ligation for comprehensive variant detection and local haplotyping

    Paula J P de Vree;Elzo de Wit;Mehmet Yilmaz;Monique van de Heijning

  • Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent.

    Yan Guo;Shaneda Warren Andersen;Xiao-Ou Shu;Kyriaki Michailidou

  • Common Breast Cancer Susceptibility Alleles and the Risk of Breast Cancer for BRCA1 and BRCA2 Mutation Carriers: Implications for Risk Prediction

    Antonis C. Antoniou;Jonathan Beesley;Lesley McGuffog;Olga M. Sinilnikova

  • Molecular analysis of the APC gene in 105 Dutch kindreds with familial adenomatous polyposis: 67 germline mutations identified by DGGE, PTT, and southern analysis.

    Rob. B. van der Luijt;P. Meera Khan;Hans F. A. Vasen;Carli M. J. Tops

  • Molecular diagnosis of pituitary adenoma predisposition caused by aryl hydrocarbon receptor-interacting protein gene mutations.

    Marianthi Georgitsi;Anniina Raitila;Auli Karhu;Karoliina Tuppurainen

  • Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer.

    Christopher A. Maxwell;Javier Benitez;Laia Gomez-Baldo;Ana Osorio

Frequent Co-Authors

Irene L. Andrulis
Irene L. Andrulis University of Toronto
Fergus J. Couch
Fergus J. Couch Mayo Clinic
Douglas F. Easton
Douglas F. Easton University of Cambridge
Heli Nevanlinna
Heli Nevanlinna University of Helsinki
Georgia Chenevix-Trench
Georgia Chenevix-Trench QIMR Berghofer Medical Research Institute
Rita K. Schmutzler
Rita K. Schmutzler University of Cologne
Alfons Meindl
Alfons Meindl Technical University of Munich
Esther M. John
Esther M. John Stanford University
Javier Benitez
Javier Benitez Instituto de Salud Carlos III
Ute Hamann
Ute Hamann German Cancer Research Center

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