Richard S. Lewis

Overview

Best Publications

• A mutation in Orai1 causes immune deficiency by abrogating CRAC channel function

  Stefan Feske;Yousang Gwack;Murali Prakriya;Sonal Srikanth

  2602
  Citations

• Differential activation of transcription factors induced by Ca2+ response amplitude and duration

  Ricardo E. Dolmetsch;Richard S. Lewis;Christopher C. Goodnow;James I. Healy

  2389
  Citations

• Calcium oscillations increase the efficiency and specificity of gene expression

  Ricardo E. Dolmetsch;Keli Xu;Richard S. Lewis

  2379
  Citations

• Store-Operated Calcium Channels

  Murali Prakriya;Richard S. Lewis

  1153
  Citations

• STIM1 Clusters and Activates CRAC Channels via Direct Binding of a Cytosolic Domain to Orai1

  Chan Young Park;Paul J. Hoover;Franklin M. Mullins;Priti Bachhawat

  1140
  Citations

• Calcium Signaling Mechanisms in T Lymphocytes

  Richard S Lewis

  1136
  Citations

• Mitogen-regulated Ca2+ current of T lymphocytes is activated by depletion of intracellular Ca2+ stores

  Adam Zweifach;Richard S. Lewis

  995
  Citations

• Ca2+ store depletion causes STIM1 to accumulate in ER regions closely associated with the plasma membrane.

  Minnie M. Wu;JoAnn Buchanan;Riina M. Luik;Richard S. Lewis

  925
  Citations

• Molecular Basis of Calcium Signaling in Lymphocytes: STIM and ORAI

  Patrick G. Hogan;Richard S. Lewis;Anjana Rao

  876
  Citations

• Role of membrane potential and hydrogen bonding in the mechanism of translocation of guanidinium-rich peptides into cells.

  Jonathan B Rothbard;Theodore C Jessop;Richard S Lewis;Bryce A Murray

  761
  Citations

• The elementary unit of store-operated Ca2+ entry: local activation of CRAC channels by STIM1 at ER–plasma membrane junctions

  Riina M. Luik;Minnie M. Wu;JoAnn Buchanan;Richard S. Lewis

  757
  Citations

• Abnormal Calcium Handling Properties Underlie Familial Hypertrophic Cardiomyopathy Pathology in Patient-Specific Induced Pluripotent Stem Cells

  Feng Lan;Andrew S. Lee;Ping Liang;Veronica Sanchez-Freire

  725
  Citations

• Oligomerization of STIM1 couples ER calcium depletion to CRAC channel activation

  Riina M. Luik;Bin Wang;Murali Prakriya;Murali Prakriya;Minnie M. Wu

  655
  Citations

• Potassium and calcium channels in lymphocytes.

  Richard S Lewis;Michael D Cahalan

  619
  Citations

• Mitochondrial Regulation of Store-operated Calcium Signaling in T Lymphocytes

  Markus Hoth;Christopher M. Fanger;Richard S. Lewis

  616
  Citations

• The molecular choreography of a store-operated calcium channel

  Richard S. Lewis

  601
  Citations

• Potentiation and inhibition of Ca2+ release‐activated Ca2+ channels by 2‐aminoethyldiphenyl borate (2‐APB) occurs independently of IP3 receptors

  Murali Prakriya;Richard S. Lewis

  581
  Citations

• Mitogen-induced oscillations of cytosolic Ca2+ and transmembrane Ca2+ current in human leukemic T cells.

  R S Lewis;M D Cahalan

  530
  Citations

• Rapid inactivation of depletion-activated calcium current (ICRAC) due to local calcium feedback.

  A Zweifach;R S Lewis

  527
  Citations

• Different nuclear signals are activated by the B cell receptor during positive versus negative signaling.

  James I Healy;Ricardo E Dolmetsch;Luika A Timmerman;Jason G Cyster

  487
  Citations