World's Best Scientists 2026 revealed!
René P. Zahedi

René P. Zahedi

D-Index & Metrics

Biology and Biochemistry

D-Index
60
Citations
13347
World Ranking
11922
National Ranking
409

Overview

René P. Zahedi is affiliated with the University of Manitoba in Canada and has contributed extensively to the fields of biochemistry, genetics, molecular biology, and medicine. Their research primarily focuses on molecular biology and has a significant output in areas such as spectroscopy, oncology, pulmonary and respiratory medicine, and hematology.

The scientist's work covers several main topics, including advanced proteomics techniques and applications, mass spectrometry techniques and applications, ubiquitin and proteasome pathways, PI3K/AKT/mTOR signaling in cancer, metabolism with a focus on diabetes and cancer, cancer involving hypoxia and metabolism, and platelet disorders and treatments.

Some of the recent papers authored or co-authored by René P. Zahedi illustrate the breadth and relevance of their research interests:

  • Hyperinsulinemia acts via acinar insulin receptors to initiate pancreatic cancer by increasing digestive enzyme production and inflammation, 2023, Cell Metabolism
  • Omics approaches for the assessment of biological responses to nanoparticles, 2023, Advanced Drug Delivery Reviews
  • Early Prediction of COVID-19 Patient Survival by Targeted Plasma Multi-Omics and Machine Learning, 2022, Molecular & Cellular Proteomics
  • Utility, promise, and limitations of liquid chromatography-mass spectrometry-based therapeutic drug monitoring in precision medicine, 2021, Journal of Mass Spectrometry
  • Mild proteasomal stress improves photosynthetic performance in Arabidopsis chloroplasts, 2020, Nature Communications

Frequent collaborators of Zahedi include Christoph H. Borchers, Vincent R. Richard, Gerald Batist, Victor Spicer, and Ying Lao. These coauthors represent a network that has contributed repeatedly to various aspects of Zahedi's research areas.

The scientist has published multiple papers in well-known academic venues. The most frequent publication outlets are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Analytical Chemistry
  • Molecular & Cellular Proteomics
  • International Journal of Molecular Sciences
  • SSRN Electronic Journal

Best Publications

  • The proteome of Saccharomyces cerevisiae mitochondria

    Albert Sickmann;Jörg Reinders;Yvonne Wagner;Cornelia Joppich

  • The first comprehensive and quantitative analysis of human platelet protein composition allows the comparative analysis of structural and functional pathways.

    Julia M. Burkhart;Marc Vaudel;Stepan Gambaryan;Sonja Radau

  • PeptideShaker enables reanalysis of MS-derived proteomics data sets

    Marc Vaudel;Julia M Burkhart;René P Zahedi;Eystein Oveland

  • Global Analysis of the Mitochondrial N-Proteome Identifies a Processing Peptidase Critical for Protein Stability

    F-Nora Vögtle;Stefanie Wortelkamp;René P Zahedi;Dorothea Becker;Dorothea Becker

  • Toward the complete yeast mitochondrial proteome: multidimensional separation techniques for mitochondrial proteomics.

    Joerg Reinders;René P. Zahedi;Nikolaus Pfanner;Chris Meisinger

  • The Protein Import Machinery of Mitochondria—A Regulatory Hub in Metabolism, Stress, and Disease

    Angelika B. Harbauer;René P. Zahedi;Albert Sickmann;Albert Sickmann;Nikolaus Pfanner

  • Systematic and quantitative comparison of digest efficiency and specificity reveals the impact of trypsin quality on MS-based proteomics.

    Julia Maria Burkhart;Cornelia Schumbrutzki;Stefanie Wortelkamp;Albert Sickmann;Albert Sickmann

  • The next level of complexity: Crosstalk of posttranslational modifications

    A. Saskia Venne;Laxmikanth Kollipara;René P. Zahedi

  • Regulation of mitochondrial protein import by cytosolic kinases.

    Oliver Schmidt;Angelika B. Harbauer;Sanjana Rao;Beate Eyrich

  • Proteomic analysis of the yeast mitochondrial outer membrane reveals accumulation of a subclass of preproteins.

    Rene P. Zahedi;Albert Sickmann;Andreas M. Boehm;Christiane Winkler

  • Amyloid-β Peptide Induces Mitochondrial Dysfunction by Inhibition of Preprotein Maturation

    Dirk Mossmann;F.-Nora Vögtle;Asli Aras Taskin;Pedro Filipe Teixeira

  • Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase.

    Jörg Reinders;Karina Wagner;Rene P. Zahedi;Diana Stojanovski

  • Intermembrane Space Proteome of Yeast Mitochondria

    F.-Nora Vögtle;Julia M. Burkhart;Sanjana Rao;Carolin Gerbeth

  • The Human Platelet Membrane Proteome Reveals Several New Potential Membrane Proteins

    Jan Moebius;Reneí Peiman Zahedi;Urs Lewandrowski;Claudia Berger

  • Phosphoproteome of resting human platelets.

    René P. Zahedi;Urs Lewandrowski;Julia Wiesner;Stefanie Wortelkamp

  • Current strategies and findings in clinically relevant post-translational modification-specific proteomics.

    Oliver Pagel;Stefan Loroch;Albert Sickmann;René P Zahedi

  • PARL mediates Smac proteolytic maturation in mitochondria to promote apoptosis

    Shotaro Saita;Hendrik Nolte;Kai Uwe Fiedler;Hamid Kashkar

  • Platelet membrane proteomics: a novel repository for functional research

    Urs Lewandrowski;Stefanie Wortelkamp;Katharina Lohrig;René P. Zahedi

  • Dual function of Sdh3 in the respiratory chain and TIM22 protein translocase of the mitochondrial inner membrane.

    Natalia Gebert;Michael Gebert;Silke Oeljeklaus;Karina von der Malsburg

  • Protein carbamylation: in vivo modification or in vitro artefact?

    Laxmikanth Kollipara;René P. Zahedi

Frequent Co-Authors

Albert Sickmann
Albert Sickmann Leibniz Institute for Neurobiology
Chris Meisinger
Chris Meisinger University of Freiburg
Lennart Martens
Lennart Martens Ghent University
Ulrich Walter
Ulrich Walter Johannes Gutenberg University of Mainz
Hanns Lochmüller
Hanns Lochmüller University of Freiburg
Joachim Weis
Joachim Weis RWTH Aachen University
Nikolaus Pfanner
Nikolaus Pfanner University of Freiburg
Christoph H. Borchers
Christoph H. Borchers McGill University
Agapios Sachinidis
Agapios Sachinidis University of Cologne
Jan G. Hengstler
Jan G. Hengstler TU Dortmund University

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