Pierre Chardin

Overview

Best Publications

• Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling.

  N. Li;A. Batzer;R. Daly;V. Yajnik

  1217
  Citations

• Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2.

  P. Chardin;J. H. Camonis;N. W. Gale;L. Van Aelst

  1062
  Citations

• Cyclic GMP-dependent Protein Kinase Signaling Pathway Inhibits RhoA-induced Ca2+ Sensitization of Contraction in Vascular Smooth Muscle

  Vincent Sauzeau;Hélène Le Jeune;Chrystelle Cario-Toumaniantz;Albert Smolenski

  756
  Citations

• The ras protein family: evolutionary tree and role of conserved amino acids.

  Alfonso Valencia;Pierre Chardin;Alfred Wittinghofer;Chris Sander

  754
  Citations

• The mammalian G protein rhoC is ADP-ribosylated by Clostridium botulinum exoenzyme C3 and affects actin microfilaments in Vero cells.

  P. Chardin;P. Boquet;P. Madaule;M. R. Popoff

  723
  Citations

• A human exchange factor for ARF contains Sec7- and pleckstrin-homology domains.

  Pierre Chardin;Sonia Paris;Bruno Antonny;Sylviane Robineau

  612
  Citations

• Toxin-induced activation of the G protein p21 Rho by deamidation of glutamine

  Gilles Flatau;Emmanuel Lemichez;Michel Gauthier;Pierre Chardin

  567
  Citations

• Diaphanous-Related Formins Bridge Rho GTPase and Src Tyrosine Kinase Signaling

  Tomoko Tominaga;Erik Sahai;Pierre Chardin;Pierre Chardin;Frank McCormick

  544
  Citations

• The Human Rab Genes Encode a Family of GTP-binding Proteins Related to Yeast YPT1 and SEC4 Products Involved in Secretion

  A Zahraoui;N Touchot;P Chardin;A Tavitian

  525
  Citations

• Four additional members of the ras gene superfamily isolated by an oligonucleotide strategy: molecular cloning of YPT-related cDNAs from a rat brain library.

  Nicolas Touchot;Pierre Chardin;Armand Tavitian

  522
  Citations

• cAMP antagonizes p21ras-directed activation of extracellular signal-regulated kinase 2 and phosphorylation of mSos nucleotide exchange factor.

  B. M. T. Burgering;G. J. Pronk;P. C. Van Weeren;P. Chardin

  498
  Citations

• GEFs: structural basis for their activation of small GTP-binding proteins

  Jacqueline Cherfils;Pierre Chardin

  480
  Citations

• A New Member of the Rho Family, Rnd1, Promotes Disassembly of Actin Filament Structures and Loss of Cell Adhesion

  Catherine D. Nobes;Inger Lauritzen;Marie-Geneviève Mattei;Sonia Paris

  478
  Citations

• Human cDNAs rap1 and rap2 homologous to the Drosophila gene Dras3 encode proteins closely related to ras in the 'effector' region.

  Pizon;Chardin P;Lerosey I;Olofsson B

  471
  Citations

• N-terminal hydrophobic residues of the G-protein ADP-ribosylation factor-1 insert into membrane phospholipids upon GDP to GTP exchange.

  Bruno Antonny;Sophie Beraud-Dufour;Pierre Chardin;Marc Chabre

  451
  Citations

• Inhibition of GTPase activating protein stimulation of Ras-p21 GTPase by the Krev-1 gene product

  Matthias Frech;Jacob John;Veronique Pizon;Pierre Chardin

  351
  Citations

• Common haplotype dependency of high G gamma-globin gene expression and high Hb F levels in beta-thalassemia and sickle cell anemia patients.

  D Labie;J Pagnier;C Lapoumeroulie;F Rouabhi

  328
  Citations

• Function and regulation of Rnd proteins

  Pierre Chardin

  292
  Citations

• Myristoylation of ADP-ribosylation factor 1 facilitates nucleotide exchange at physiological Mg2+ levels.

  Michel Franco;Pierre Chardin;Marc Chabre;Sonia Paris

  260
  Citations

• Ras, Rap, and Rac Small GTP-binding Proteins Are Targets for Clostridium sordellii Lethal Toxin Glucosylation

  Michel R. Popoff;Esteban Chaves-Olarte;Emmanuel Lemichez;Emmanuel Lemichez;Christoph von Eichel-Streiber

  254
  Citations