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Microbiology

D-Index
48
Citations
8524
World Ranking
4684
National Ranking
1808

Overview

Patricia J. Simner is affiliated with Johns Hopkins University School of Medicine in the United States. Their research spans multiple aspects of infectious diseases, clinical biochemistry, and molecular medicine, with a focus on antimicrobial resistance and bacterial identification. The scientist has contributed extensively to studies related to antibiotic resistance, antibiotic pharmacokinetics, and bacterial susceptibility testing.

The main fields of study covered in Patricia J. Simner's work include Biochemistry, Genetics and Molecular Biology, and Medicine. Subfields where they have a notable publication record include Molecular Medicine, Clinical Biochemistry, Infectious Diseases, Pharmacology, and Epidemiology.

Their research addresses various topics, mainly:

  • Antibiotic Resistance in Bacteria
  • Bacterial Identification and Susceptibility Testing
  • Antibiotics Pharmacokinetics and Efficacy
  • Antibiotic Use and Resistance
  • Antimicrobial Resistance in Staphylococcus
  • Mycobacterium research and diagnosis
  • Gut microbiota and health

Frequent collaborators of Patricia J. Simner include Pranita D. Tamma, Yehudit Bergman, Romney M. Humphries, Emily Jacobs, and Karen C. Carroll.

The scientist has published extensively in several peer-reviewed journals. The most frequent publication venues are:

  • Journal of Clinical Microbiology
  • Open Forum Infectious Diseases
  • Clinical Infectious Diseases
  • Antimicrobial Agents and Chemotherapy
  • ClinMicroNow

Recent papers authored or co-authored by Patricia J. Simner include:

  • "Extended-spectrum β-lactamases: an update on their characteristics, epidemiology and detection," 2021, JAC-Antimicrobial Resistance
  • "Metagenomic Next-Generation Sequencing of Nasopharyngeal Specimens Collected from Confirmed and Suspect COVID-19 Patients," 2020, mBio
  • "Evaluation of Metagenomic and Targeted Next-Generation Sequencing Workflows for Detection of Respiratory Pathogens from Bronchoalveolar Lavage Fluid Specimens," 2022, Journal of Clinical Microbiology
  • "Cefiderocol Antimicrobial Susceptibility Testing Considerations: the Achilles' Heel of the Trojan Horse?", 2020, Journal of Clinical Microbiology
  • "Comparing the analytical performance of three SARS-CoV-2 molecular diagnostic assays," 2020, Journal of Clinical Virology

Best Publications

  • Understanding the Promises and Hurdles of Metagenomic Next-Generation Sequencing as a Diagnostic Tool for Infectious Diseases.

    Patricia J Simner;Steven Miller;Karen C Carroll

  • Extended-spectrum β-lactamases: an update on their characteristics, epidemiology and detection

    Mariana Castanheira;Patricia J Simner;Patricia A Bradford

  • Comparing the Outcomes of Patients With Carbapenemase-Producing and Non-Carbapenemase-Producing Carbapenem-Resistant Enterobacteriaceae Bacteremia

    Pranita D. Tamma;Katherine E. Goodman;Anthony D. Harris;Tsigereda Tekle

  • Modified Carbapenem Inactivation Method for Phenotypic Detection of Carbapenemase Production among Enterobacteriaceae

    Virginia M. Pierce;Patricia J. Simner;David R. Lonsway;Darcie E. Roe-Carpenter

  • A Primer on AmpC β-Lactamases: Necessary Knowledge for an Increasingly Multidrug-resistant World.

    Pranita D Tamma;Yohei Doi;Robert A Bonomo;J Kristie Johnson

  • Phenotypic Detection of Carbapenemase-Producing Organisms from Clinical Isolates.

    Pranita D. Tamma;Patricia J. Simner

  • Can Multidrug-Resistant Candida auris Be Reliably Identified in Clinical Microbiology Laboratories?

    Masako Mizusawa;Heather Miller;Rachel Green;Richard Lee

  • Evaluation of Metagenomic and Targeted Next-Generation Sequencing Workflows for Detection of Respiratory Pathogens from Bronchoalveolar Lavage Fluid Specimens

    Unknown

  • Molecular epidemiology of extended-spectrum β-lactamase-, AmpC β-lactamase- and carbapenemase-producing Escherichia coli and Klebsiella pneumoniae isolated from Canadian hospitals over a 5 year period: CANWARD 2007–11

    Andrew J Denisuik;Philippe R S Lagacé-Wiens;Philippe R S Lagacé-Wiens;Johann D Pitout;Michael R Mulvey;Michael R Mulvey

  • Antimicrobial Resistance in Urinary Tract Pathogens in Canada from 2007 to 2009: CANWARD Surveillance Study

    James A. Karlowsky;Philippe R. S. Lagacé-Wiens;Patricia J. Simner;Melanie R. DeCorby

  • Multicenter Evaluation of the Accelerate PhenoTest™ BC Kit for Rapid Identification and Phenotypic Antimicrobial Susceptibility Testing Using Morphokinetic Cellular Analysis

    Preeti Pancholi;Karen C. Carroll;Blake W. Buchan;Raymond C. Chan

  • Metagenomic Next-Generation Sequencing of Nasopharyngeal Specimens Collected from Confirmed and Suspect COVID-19 Patients

    Heba H. Mostafa;John A. Fissel;Brian Fanelli;Yehudit Bergman

  • Comparison of a Novel, Rapid Chromogenic Biochemical Assay, the Carba NP Test, with the Modified Hodge Test for Detection of Carbapenemase-Producing Gram-Negative Bacilli

    Shawn Vasoo;Scott A. Cunningham;Peggy C. Kohner;Patricia J. Simner

  • Human Colon Cancer–Derived Clostridioides difficile Strains Drive Colonic Tumorigenesis in Mice

    Unknown

  • Cefiderocol Antimicrobial Susceptibility Testing Considerations: the Achilles' Heel of the Trojan Horse?

    Patricia J. Simner;Robin Patel

  • Comparison of 11 Phenotypic Assays for Accurate Detection of Carbapenemase-Producing Enterobacteriaceae

    Pranita D. Tamma;Belita N. A. Opene;Andrew Gluck;Krizia K. Chambers

  • Infection control implications of heterogeneous resistance mechanisms in carbapenem-resistant Enterobacteriaceae (CRE)

    KE Goodman;PJ Simner;PD Tamma;AM Milstone

  • Next-Generation Sequencing in Clinical Microbiology: Are We There Yet?

    Stephanie L. Mitchell;Patricia J. Simner

  • Carbapenem-Resistant Non-Glucose-Fermenting Gram-Negative Bacilli: the Missing Piece to the Puzzle.

    Thomas J. Gniadek;Karen C. Carroll;Patricia J. Simner

  • Comparing the analytical performance of three SARS-CoV-2 molecular diagnostic assays.

    Katharine Uhteg;Junko Jarrett;Mahmia Richards;Craig Howard

  • Activity of NXL104 in Combination with β-Lactams against Genetically Characterized Escherichia coli and Klebsiella pneumoniae Isolates Producing Class A Extended-Spectrum β-Lactamases and Class C β-Lactamases

    P. R. S. Lagacé-Wiens;F. Tailor;P. Simner;M. DeCorby

  • EDTA-Modified Carbapenem Inactivation Method: a Phenotypic Method for Detecting Metallo-β-Lactamase-Producing Enterobacteriaceae.

    M. M. Sfeir;J. A. Hayden;K. A. Fauntleroy;C. Mazur

  • Prevalence and characterization of extended-spectrum β-lactamase- and AmpC β-lactamase-producing Escherichia coli: results of the CANWARD 2007-2009 study.

    Patricia J. Simner;George G. Zhanel;Johann Pitout;Franil Tailor

Frequent Co-Authors

Karen C. Carroll
Karen C. Carroll Johns Hopkins University School of Medicine
Philippe R. S. Lagacé-Wiens
Philippe R. S. Lagacé-Wiens University of Manitoba
James A. Karlowsky
James A. Karlowsky University of Manitoba
George G. Zhanel
George G. Zhanel University of Manitoba
Daryl J. Hoban
Daryl J. Hoban University of Manitoba
Michael C. Schatz
Michael C. Schatz Johns Hopkins University
Heather J. Adam
Heather J. Adam University of Manitoba
Stephen G. Jenkins
Stephen G. Jenkins Cornell University
Michael R. Mulvey
Michael R. Mulvey University of Manitoba

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