D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 56 Citations 10,567 183 World Ranking 9971 National Ranking 280

Overview

What is she best known for?

The fields of study she is best known for:

  • Gene
  • Cancer
  • DNA

Her primary scientific interests are in Cancer research, Apoptosis, Cisplatin, Drug resistance and Cell culture. Her Cancer research study integrates concerns from other disciplines, such as Cytotoxic T cell, Lung cancer, Immunology and Cytotoxicity. The study incorporates disciplines such as Tumor suppressor gene, Tumor progression and DNA damage in addition to Apoptosis.

The various areas that she examines in her Cisplatin study include Ovarian carcinoma, Ovarian cancer, Oxaliplatin and Platinum Compound. Her research integrates issues of Camptothecin and Tumour heterogeneity in her study of Drug resistance. Her studies deal with areas such as Endocrinology and Internal medicine as well as Cell culture.

Her most cited work include:

  • Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment. (601 citations)
  • Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles. (598 citations)
  • Inhibition of proteasome deubiquitinating activity as a new cancer therapy (355 citations)

What are the main themes of her work throughout her whole career to date?

Paola Perego mainly investigates Cancer research, Cisplatin, Apoptosis, Cell culture and Pharmacology. Her Cancer research research incorporates themes from Cell, Cancer, Internal medicine, Immunology and Cytotoxicity. Her Cisplatin research is multidisciplinary, incorporating elements of Osteosarcoma, Ovarian carcinoma, Ovarian cancer, Oxaliplatin and Molecular biology.

Her Apoptosis research includes elements of Tumor suppressor gene, Cytotoxic T cell, DNA damage and In vivo. Her Cell culture research is multidisciplinary, incorporating perspectives in Caspase 3, A431 cells, Biochemistry and Melanoma. Paola Perego combines subjects such as Camptothecin, Cancer cell, Topotecan, Topoisomerase and Drug resistance with her study of Pharmacology.

She most often published in these fields:

  • Cancer research (47.22%)
  • Cisplatin (33.33%)
  • Apoptosis (23.89%)

What were the highlights of her more recent work (between 2014-2021)?

  • Cancer research (47.22%)
  • Pharmacology (16.67%)
  • Apoptosis (23.89%)

In recent papers she was focusing on the following fields of study:

Her primary areas of investigation include Cancer research, Pharmacology, Apoptosis, Cisplatin and Cancer. She interconnects Cell, Cell growth, Tyrosine-kinase inhibitor, Cytotoxic T cell and In vivo in the investigation of issues within Cancer research. Her biological study spans a wide range of topics, including Cell culture, DNA damage, Ovarian carcinoma, Receptor and Drug resistance.

Her Apoptosis study combines topics in areas such as Drug interaction, microRNA and Transcription factor. Paola Perego has included themes like Lung cancer, Oxaliplatin and DNA repair in her Cisplatin study. Her study looks at the relationship between DNA repair and topics such as Topoisomerase, which overlap with Molecular biology.

Between 2014 and 2021, her most popular works were:

  • Resistance mechanisms to osimertinib in EGFR-mutated non-small cell lung cancer. (130 citations)
  • Microenvironment-Modulated Metastatic CD133+/CXCR4+/EpCAM- Lung Cancer-Initiating Cells Sustain Tumor Dissemination and Correlate with Poor Prognosis. (56 citations)
  • New mechanisms for old drugs: Insights into DNA-unrelated effects of platinum compounds and drug resistance determinants (33 citations)

In her most recent research, the most cited papers focused on:

  • Gene
  • Cancer
  • DNA

Paola Perego spends much of her time researching Cancer research, Cell growth, Pharmacology, Drug resistance and Cisplatin. With her scientific publications, her incorporates both Cancer research and Peptidomimetic. Her research investigates the connection with Cell growth and areas like Cancer cell which intersect with concerns in Intracellular, Biochemistry and Antioxidant.

Her Pharmacology research focuses on DNA damage and how it relates to PKC alpha, Transfection, Ovarian carcinoma, microRNA and Apoptosis. Her Drug resistance study combines topics from a wide range of disciplines, such as Tumor microenvironment, Immune system, Programmed cell death, Platinum Compound and Mitochondrion. Her work carried out in the field of Cisplatin brings together such families of science as FOXO1, Transcription factor, Oxaliplatin and DNA repair.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Highly tumorigenic lung cancer CD133+ cells display stem-like features and are spared by cisplatin treatment.

Giulia Bertolini;Luca Roz;Paola Perego;Monica Tortoreto.
Proceedings of the National Academy of Sciences of the United States of America (2009)

931 Citations

Induction of lymphocyte apoptosis by tumor cell secretion of FasL-bearing microvesicles.

Giovanna Andreola;Licia Rivoltini;Chiara Castelli;Veronica Huber.
Journal of Experimental Medicine (2002)

857 Citations

Association between Cisplatin Resistance and Mutation of p53 Gene and Reduced Bax Expression in Ovarian Carcinoma Cell Systems

Paola Perego;Monica Giarola;Sabina C. Righetti;Rosanna Supino.
Cancer Research (1996)

493 Citations

Inhibition of proteasome deubiquitinating activity as a new cancer therapy

Pádraig D'Arcy;Slavica Brnjic;Maria Hägg Olofsson;Mårten Fryknäs.
Nature Medicine (2011)

443 Citations

Expression of the anti-apoptotic gene survivin correlates with taxol resistance in human ovarian cancer.

N. Zaffaroni;M. Pennati;G. Colella;P. Perego.
Cellular and Molecular Life Sciences (2002)

405 Citations

A novel trinuclear platinum complex overcomes cisplatin resistance in an osteosarcoma cell system.

Paola Perego;Claudia Caserini;Laura Gatti;Nives Carenini.
Molecular Pharmacology (1999)

197 Citations

A proteomic approach to cisplatin resistance in the cervix squamous cell carcinoma cell line A431.

Annalisa Castagna;Paolo Antonioli;Hubert Astner;Malimoud Hamdan.
Proteomics (2004)

183 Citations

In vitro and in vivo interaction between cisplatin and topotecan in ovarian carcinoma systems

Simona Romanelli;Paola Perego;Graziella Pratesi;Nives Carenini.
Cancer Chemotherapy and Pharmacology (1998)

166 Citations

p53 Gene Status and Response to Platinum/Paclitaxel-Based Chemotherapy in Advanced Ovarian Carcinoma

Cinzia Lavarino;Silvana Pilotti;Maria Oggionni;Laura Gatti.
Journal of Clinical Oncology (2000)

166 Citations

A novel charged trinuclear platinum complex effective against cisplatin-resistant tumours: hypersensitivity of p53-mutant human tumour xenografts

G Pratesi;P Perego;D Polizzi;S C Righetti.
British Journal of Cancer (1999)

158 Citations

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