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Biology and Biochemistry

D-Index
63
Citations
17938
World Ranking
10056
National Ranking
771

Overview

Olivia Fletcher is affiliated with the Institute of Cancer Research in the United Kingdom. Their research focuses on genetics, molecular biology, and oncology, with a significant portion of work dedicated to biochemistry, genetics, and molecular biology fields. They have contributed extensively to understanding cancer genetics and related epidemiological factors.

The main topics covered in Olivia Fletcher's scientific contributions include:

  • BRCA gene mutations in cancer
  • Genetic associations and epidemiology
  • Nutrition, genetics, and disease
  • Bioinformatics and genomic networks
  • Genomics and chromatin dynamics
  • Epigenetics and DNA methylation
  • Gene expression and cancer classification

Several recent papers highlight key research efforts led or co-authored by Fletcher:

  • Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes, 2020, Nature Genetics
  • Physical activity, sedentary time and breast cancer risk: a Mendelian randomisation study, 2022, British Journal of Sports Medicine
  • Transcriptome-wide association study of breast cancer risk by estrogen-receptor status, 2020, Genetic Epidemiology
  • Understanding the genetic complexity of puberty timing across the allele frequency spectrum, 2024, Nature Genetics
  • Evaluation of the Association of Polymorphisms With Palbociclib-Induced Neutropenia: Pharmacogenetic Analysis of PALOMA-2/-3, 2021, The Oncologist

Olivia Fletcher collaborates frequently with various researchers in related disciplines and has maintained productive partnerships with notable co-authors, including:

  • Manjeet K. Bolla
  • Hermann Brenner
  • Kamila Czene
  • Thilo Dörk
  • Stig E. Bojesen

The scientist's publications have appeared prominently in venues known for their contributions to cancer and genetics research, such as:

  • UNC Libraries
  • Nature Genetics
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Clinical Oncology
  • British Journal of Sports Medicine

Olivia Fletcher's work spans a range of subfields within their discipline, with contributions recorded in genetics, molecular biology, oncology, public health, environmental and occupational health, and immunology. This diverse expertise supports interdisciplinary approaches to cancer research and genomic studies.

Best Publications

  • Genome-wide association study identifies novel breast cancer susceptibility loci

    Douglas F. Easton;Karen A. Pooley;Alison M. Dunning;Paul D. P. Pharoah

  • Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

    Bjarni J. Vilhjálmsson;Jian Yang;Hilary K. Finucane;Alexander Gusev

  • Association analysis identifies 65 new breast cancer risk loci

    Kyriaki Michailidou;Kyriaki Michailidou;Sara Lindström;Sara Lindström;Joe Dennis;Jonathan Beesley

  • Large-scale genotyping identifies 41 new loci associated with breast cancer risk

    Kyriaki Michailidou;Per Hall;Anna Gonzalez-Neira;Maya Ghoussaini

  • Polygenic Risk Scores for Prediction of Breast Cancer and Breast Cancer Subtypes

    Nasim Mavaddat;Kyriaki Michailidou;Kyriaki Michailidou;Joe Dennis;Michael Lush

  • A common coding variant in CASP8 is associated with breast cancer risk

    Angela Cox;Alison M. Dunning;Montserrat Garcia-Closas;Sabapathy Balasubramanian

  • Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

    Kyriaki Michailidou;Jonathan Beesley;Sara Lindstrom;Sander Canisius

  • Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer

    Stig E. Bojesen;Stig E. Bojesen;Karen A. Pooley;Sharon E. Johnatty;Jonathan Beesley

  • MicroRNA related polymorphisms and breast cancer risk

    Sofia Khan;Dario Greco;Dario Greco;Kyriaki Michailidou;Roger L. Milne;Roger L. Milne

  • Newly discovered breast cancer susceptibility loci on 3p24 and 17q23.2.

    Shahana Ahmed;Gilles Thomas;Maya Ghoussaini;Catherine S. Healey

  • Genome-wide association studies identify four ER negative-specific breast cancer risk loci

    Montserrat Garcia-Closas;Fergus J. Couch;Sara Lindstrom;Kyriaki Michailidou

  • Lifetime Risks of Common Cancers Among Retinoblastoma Survivors

    Olivia Fletcher;Douglas Easton;Kristin Anderson;Clare Gilham

  • Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer.

    Roger L Milne;Roger L Milne;Karoline B Kuchenbaecker;Karoline B Kuchenbaecker;Kyriaki Michailidou;Kyriaki Michailidou;Jonathan Beesley

  • Genome-wide association analysis identifies three new breast cancer susceptibility loci

    Maya Ghoussaini;Olivia Fletcher;Kyriaki Michailidou;Clare Turnbull

  • Novel breast cancer susceptibility locus at 9q31.2: results of a genome-wide association study.

    Olivia Fletcher;Nichola Johnson;Nick Orr;Fay J. Hosking

  • Architecture of inherited susceptibility to common cancer

    Olivia Fletcher;Richard S. Houlston

  • Unbiased analysis of potential targets of breast cancer susceptibility loci by Capture Hi-C

    Nicola H. Dryden;Laura R. Broome;Frank Dudbridge;Nichola Johnson

  • Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent.

    Yan Guo;Shaneda Warren Andersen;Xiao-Ou Shu;Kyriaki Michailidou

  • Evidence of gene-environment interactions between common breast cancer susceptibility loci and established environmental risk factors.

    Stefan Nickels;Thérèse Truong;Rebecca Hein;Kristen N. Stevens

  • ARTICLES Lifetime Risks of Common Cancers Among Retinoblastoma Survivors

    Olivia Fletcher;Douglas Easton;Kristin Anderson;Clare Gilham

Frequent Co-Authors

Hiltrud Brauch
Hiltrud Brauch German Cancer Research Center
Graham G. Giles
Graham G. Giles University of Melbourne
Peter A. Fasching
Peter A. Fasching University of Erlangen-Nuremberg
Roger L. Milne
Roger L. Milne Cancer Council Victoria
Julian Peto
Julian Peto London School of Hygiene & Tropical Medicine
Stig E. Bojesen
Stig E. Bojesen University of Copenhagen
Melissa C. Southey
Melissa C. Southey Monash University
Barbara Burwinkel
Barbara Burwinkel Heidelberg University
Jenny Chang-Claude
Jenny Chang-Claude German Cancer Research Center
Irene L. Andrulis
Irene L. Andrulis University of Toronto

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