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Biology and Biochemistry
UK
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
93
Citations
36630
World Ranking
2078
National Ranking
136

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in United Kingdom Leader Award
  • 2017 - Member of Academia Europaea

Overview

Nigel M. Hooper is affiliated with the Manchester Academic Health Science Centre in the United Kingdom. The scientist's research encompasses a wide range of topics primarily within medicine and biochemistry, genetics, and molecular biology.

Their work spans key subfields including:

  • Neurology
  • Physiology
  • Molecular Biology
  • Cellular and Molecular Neuroscience
  • Biomedical Engineering

Research topics covered in their publications include:

  • Alzheimer's disease research and treatments
  • 3D Printing in Biomedical Research
  • Parkinson's Disease Mechanisms and Treatments
  • Neuropeptides and Animal Physiology
  • Trace Elements in Health
  • Heavy Metal Exposure and Toxicity
  • Metabolomics and Mass Spectrometry Studies

Among recent papers authored or co-authored by Nigel M. Hooper are:

  • "Mild Cognitive Impairment: the Manchester consensus," 2020, Age and Ageing
  • "3D hydrogel models of the neurovascular unit to investigate blood-brain barrier dysfunction," 2021, Neuronal Signaling
  • "Widespread Decreases in Cerebral Copper Are Common to Parkinson's Disease Dementia and Alzheimer's Disease Dementia," 2021, Frontiers in Aging Neuroscience
  • "Substantively Lowered Levels of Pantothenic Acid (Vitamin B5) in Several Regions of the Human Brain in Parkinson's Disease Dementia," 2021, Metabolites
  • "Exploiting the neuroprotective effects of α-klotho to tackle ageing- and neurodegeneration-related cognitive dysfunction," 2021, Neuronal Signaling

The scientist frequently publishes work in venues such as:

  • Neuronal Signaling
  • Metabolites
  • Cerebral Circulation - Cognition and Behavior
  • Age and Ageing
  • Frontiers in Aging Neuroscience

Collaborative efforts are a notable aspect of their career, with frequent co-authors including:

  • Katherine A. B. Kellett
  • Kate Fisher
  • Melissa Scholefield
  • Stephanie J. Church
  • Jingshu Xu

Nigel M. Hooper's contributions have been recognized through awards such as becoming a Member of Academia Europaea in 2017.

Best Publications

  • A Human Homolog of Angiotensin-converting Enzyme CLONING AND FUNCTIONAL EXPRESSION AS A CAPTOPRIL-INSENSITIVE CARBOXYPEPTIDASE

    Sarah R. Tipnis;Nigel M. Hooper;Ralph Hyde;Eric Karran

  • Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease.

    Paul Hollingworth;Denise Harold;Rebecca Sims;Amy Gerrish

  • Families of zinc metalloproteases

    Nigel M. Hooper

  • Membrane protein secretases

    Nigel M. Hooper;Eric H. Karran;Anthony J. Turner

  • Tumor necrosis factor-α convertase (ADAM17) mediates regulated ectodomain shedding of the severe-acute respiratory syndrome-coronavirus (SARS-CoV) receptor, angiotensin-converting enzyme-2 (ACE2)

    Daniel W. Lambert;Mike Yarski;Fiona J. Warner;Paul Thornhill

  • Evaluation of angiotensin-converting enzyme (ACE), its homologue ACE2 and neprilysin in angiotensin peptide metabolism

    Gillian I. Rice;Gillian I. Rice;Daniel A. Thomas;Peter J. Grant;Anthony J. Turner

  • ACE2: from vasopeptidase to SARS virus receptor

    Anthony J Turner;Julian A Hiscox;Nigel M Hooper

  • ADAMs family members as amyloid precursor protein α-secretases

    Tobias M. J. Allinson;Edward T. Parkin;Anthony J. Turner;Nigel M. Hooper

  • Detergent-insoluble glycosphingolipid/cholesterol-rich membrane domains, lipid rafts and caveolae (review).

    Nigel M. Hooper

  • The angiotensin–converting enzyme gene family: genomics and pharmacology

    Anthony J Turner;Nigel M Hooper

  • Rare coding variants in the phospholipase D3 gene confer risk for Alzheimer’s disease

    C Cruchaga;CM Karch;SC Jin;BA Benitez

  • The emerging role of ACE2 in physiology and disease

    Inge Hamming;M. E. Cooper;B. L. Haagmans;N. M. Hooper

  • Purification and characterization of smooth muscle cell caveolae.

    Wen-Jinn Chang;Yun-Shu Ying;K. G. Rothberg;N. M. Hooper

  • Exclusively targeting beta-secretase to lipid rafts by GPI-anchor addition up-regulates beta-site processing of the amyloid precursor protein.

    Joanna M. Cordy;Ishrut Hussain;Colin Dingwall;Nigel M. Hooper

  • The prion protein and lipid rafts.

    David R. Taylor;Nigel M. Hooper

  • Cellular prion protein regulates beta-secretase cleavage of the Alzheimer's amyloid precursor protein

    Edward T Parkin;Nicole T Watt;Ishrut Hussain;Elizabeth A Eckman

  • A novel Alzheimer disease locus located near the gene encoding tau protein

    G. Jun;C. A. Ibrahim-Verbaas;M. Vronskaya;J-C Lambert;J-C Lambert;J-C Lambert

  • Ablation of the metal ion-induced endocytosis of the prion protein by disease-associated mutation of the octarepeat region

    W.Sumudhu S. Perera;Nigel M. Hooper

  • Ectoenzymes of the kidney microvillar membrane. Differential solubilization by detergents can predict a glycosyl-phosphatidylinositol membrane anchor.

    N M Hooper;A J Turner

  • Amyloid-β Receptors: The Good, the Bad, and the Prion Protein

    Heledd H. Jarosz-Griffiths;Elizabeth Noble;Jo V. Rushworth;Nigel M. Hooper

Frequent Co-Authors

Anthony J. Turner
Anthony J. Turner University of Leeds
Garth J. S. Cooper
Garth J. S. Cooper University of Auckland
Jean Manson
Jean Manson University of Edinburgh
Peter J. Grant
Peter J. Grant University of Leeds
Uwe Lendeckel
Uwe Lendeckel Greifswald University Hospital
Gillian I. Rice
Gillian I. Rice University of Manchester
Pedro Piccardo
Pedro Piccardo University of Edinburgh
Helen Parkinson
Helen Parkinson European Bioinformatics Institute
Maria Jesus Martin
Maria Jesus Martin European Bioinformatics Institute

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