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Nicholas John Craddock

Nicholas John Craddock

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Psychology
UK
2026

D-Index & Metrics

Psychology

D-Index
129
Citations
101307
World Ranking
172
National Ranking
29

Medicine

D-Index
134
Citations
106296
World Ranking
2095
National Ranking
222

Research.com Recognitions

  • 2026 - Research.com Psychology in United Kingdom Leader Award

Overview

Nicholas John Craddock is affiliated with Cardiff University in the United Kingdom. Their research primarily focuses on the intersection of genetics, genomics, and psychiatric disorders, contributing to the understanding of rare genetic variants and their role in mental health conditions.

Their recent publications cover a range of topics related to genetic associations and psychiatric illnesses. Notable papers include:

  • Rare coding variants in ten genes confer substantial risk for schizophrenia (2022, Nature)
  • Exome sequencing in bipolar disorder identifies AKAP11 as a risk gene shared with schizophrenia (2022, Nature Genetics)
  • Perinatal sleep disruption and postpartum psychosis in bipolar disorder: Findings from the UK BDRN Pregnancy Study (2023, Journal of Affective Disorders)
  • Exome sequencing in bipolar disorder reveals shared risk gene AKAP11 with schizophrenia (2021, bioRxiv - Cold Spring Harbor Laboratory)
  • Distinct genetic liability profiles define clinically relevant patient strata across common diseases (2024, Nature Communications)

These works highlight cross-disorder genetic risk factors, especially between schizophrenia and bipolar disorder, as well as investigations into maternal mental health and perinatal factors.

Common co-authors in Craddock's research include:

  • Andrew McQuillin
  • Andrew M. McIntosh
  • Jordan W. Smoller
  • Douglas Blackwood
  • Aiden Corvin

They have published in several prominent academic venues, including:

  • Nature
  • Nature Genetics
  • Journal of Affective Disorders
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications

Craddock's main field of study is Biochemistry, Genetics and Molecular Biology, with an emphasis on genetic research in psychiatry. Their work spans several subfields:

  • Genetics
  • Psychiatry and Mental Health
  • Public Health, Environmental and Occupational Health
  • Experimental and Cognitive Psychology
  • Economics and Econometrics

Key research topics covered in their publications include:

  • Genomics and Rare Diseases
  • Genetic Associations and Epidemiology
  • Bipolar Disorder and Treatment
  • Genetics and Neurodevelopmental Disorders
  • Genomic Variations and Chromosomal Abnormalities
  • Maternal Mental Health During Pregnancy and Postpartum
  • Sleep and Related Disorders

Best Publications

  • Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

    Paul R. Burton;David G. Clayton;Lon R. Cardon;Nick Craddock

  • Biological insights from 108 schizophrenia-associated genetic loci

    Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Aiden Corvin;James T. R. Walters

  • Common polygenic variation contributes to risk of schizophrenia and bipolar disorder

    Shaun M. Purcell;Shaun M. Purcell;Naomi R. Wray;Jennifer L. Stone;Jennifer L. Stone;Peter M. Visscher

  • Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

    Jordan W. Smoller;Kenneth Kendler;Nicholas John Craddock;Phil Hyoun Lee

  • Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

    Naomi R. Wray;Stephan Ripke;Stephan Ripke;Stephan Ripke;Manuel Mattheisen;MacIej Trzaskowski

  • Genome-wide association study identifies five new schizophrenia loci

    Stephan Ripke;Alan R. Sanders;Kenneth S. Kendler;Douglas F. Levinson

  • Genetic relationship between five psychiatric disorders estimated from genome-wide SNPs

    S. Hong Lee;Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Stephen V. Faraone

  • Analysis of shared heritability in common disorders of the brain

    Verneri Anttila;Verneri Anttila;Brendan Bulik-Sullivan;Brendan Bulik-Sullivan;Hilary K. Finucane;Raymond K. Walters;Raymond K. Walters

  • Genome-wide association analysis identifies 13 new risk loci for schizophrenia

    Stephan Ripke;Stephan Ripke;Colm T. O'Dushlaine;Kimberly D. Chambert;Jennifer L. Moran

  • Genome-wide association study identifies 30 loci associated with bipolar disorder

    Eli A. Stahl;Eli A. Stahl;Gerome Breen;Andreas J. Forstner;Andrew McQuillin

  • Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

    Pamela Sklar;Pamela Sklar;Stephan Ripke;Stephan Ripke;Laura J. Scott;Ole A. Andreassen

  • Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

    Bjarni J. Vilhjálmsson;Jian Yang;Hilary K. Finucane;Alexander Gusev

  • Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

    Niamh Mullins;Andreas J. Forstner;Andreas J. Forstner;Andreas J. Forstner;Kevin S. O'Connell;Kevin S. O'Connell;Brandon Coombes

  • Genome-wide association study identifies eight loci associated with blood pressure

    Christopher Newton-Cheh;Christopher Newton-Cheh;Toby Johnson;Toby Johnson;Vesela Gateva;Martin D. Tobin

  • Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder

    Manuel A R Ferreira;Michael C O'Donovan;Yan A Meng;Ian R Jones

  • Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants

    Paul R Burton;David G Clayton;Lon R Cardon;Nick Craddock

  • Rare chromosomal deletions and duplications increase risk of schizophrenia

    Jennifer L. Stone;Jennifer L. Stone;Jennifer L. Stone;Michael C. O’Donovan;Hugh Gurling;George K. Kirov

  • Genomic Relationships, Novel Loci, and Pleiotropic Mechanisms across Eight Psychiatric Disorders

    Phil H. Lee;Verneri Anttila;Hyejung Won;Yen-Chen A. Feng

  • Identification of loci associated with schizophrenia by genome-wide association and follow-up

    Michael C. O'Donovan;Nicholas Craddock;Nadine Norton;Hywel Williams

  • A mega-analysis of genome-wide association studies for major depressive disorder

    Stephan Ripke;Naomi R Wray;Cathryn M Lewis;Steven P Hamilton

  • A mega-analysis of genome-wide association studies for major depressive disorder

    S. Ripke;N. R. Wray;C. M. Lewis;S. P. Hamilton

Frequent Co-Authors

Michael John Owen
Michael John Owen Cardiff University
Ian Jones
Ian Jones Cardiff University
Michael Conlon O'Donovan
Michael Conlon O'Donovan Cardiff University
Lisa Jones
Lisa Jones University of Worcester
Katherine Gordon-Smith
Katherine Gordon-Smith University of Worcester
Peter McGuffin
Peter McGuffin King's College London
George Kirov
George Kirov Cardiff University
Peter Holmans
Peter Holmans Cardiff University
Michael Gill
Michael Gill Trinity College Dublin
Marcella Rietschel
Marcella Rietschel Heidelberg University

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