D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 61 Citations 14,931 93 World Ranking 7349 National Ranking 3380

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

Mu-En Lee mostly deals with Vascular smooth muscle, Internal medicine, Endocrinology, Molecular biology and Heme oxygenase. His Vascular smooth muscle research incorporates elements of Homocysteine, Biochemistry, Cell biology, Cell cycle and In vivo. His study in the field of Endothelium, Plasminogen activator and Suprachiasmatic nucleus also crosses realms of Umbilical vein.

He interconnects Neuropeptide and PAS domain, Transcription factor in the investigation of issues within Endocrinology. The study incorporates disciplines such as Regulation of gene expression, Regulator gene, GATAD2B, Consensus sequence and Transcription in addition to Molecular biology. Mu-En Lee combines subjects such as Hypoxia, Nitric oxide and Pharmacology with his study of Heme oxygenase.

His most cited work include:

  • Promotion of vascular smooth muscle cell growth by homocysteine: a link to atherosclerosis (735 citations)
  • Tumor necrosis factor downregulates an endothelial nitric oxide synthase mRNA by shortening its half-life. (691 citations)
  • SMOOTH MUSCLE CELL-DERIVED CARBON MONOXIDE IS A REGULATOR OF VASCULAR CGMP (640 citations)

What are the main themes of his work throughout his whole career to date?

Mu-En Lee spends much of his time researching Molecular biology, Vascular smooth muscle, Cell biology, Internal medicine and Endocrinology. His biological study spans a wide range of topics, including Transfection, Complementary DNA, Gene, Regulation of gene expression and Transcription. His Vascular smooth muscle study integrates concerns from other disciplines, such as Cell, Cell growth, In situ hybridization, Neural crest and Myosin.

The various areas that Mu-En Lee examines in his Cell growth study include Cyclin A and In vivo. The Cell biology study combines topics in areas such as Growth factor, Smooth muscle cell differentiation, Cellular differentiation and Gene expression. His research integrates issues of Endothelin receptor, Atheroma and Heme oxygenase in his study of Endocrinology.

He most often published in these fields:

  • Molecular biology (56.73%)
  • Vascular smooth muscle (33.65%)
  • Cell biology (30.77%)

What were the highlights of his more recent work (between 2000-2008)?

  • Heme oxygenase (12.50%)
  • Cell biology (30.77%)
  • Internal medicine (24.04%)

In recent papers he was focusing on the following fields of study:

Mu-En Lee mainly investigates Heme oxygenase, Cell biology, Internal medicine, Endocrinology and Gene expression. His studies in Heme oxygenase integrate themes in fields like Kidney, Nitric oxide, Pharmacology and Vasodilation. His studies deal with areas such as Smooth muscle cell differentiation and Carboxypeptidase as well as Cell biology.

His Endocrinology study often links to related topics such as Endothelin receptor. His Gene expression research is multidisciplinary, incorporating perspectives in Regulation of gene expression, Transcription factor, Vascular smooth muscle and Transfection. In his research, Molecular biology is intimately related to Cryptochrome, which falls under the overarching field of Regulation of gene expression.

Between 2000 and 2008, his most popular works were:

  • Heme oxygenase-1 protects against vascular constriction and proliferation. (461 citations)
  • Cardiac-Specific Expression of Heme Oxygenase-1 Protects Against Ischemia and Reperfusion Injury in Transgenic Mice (380 citations)
  • Akt participation in the Wnt signaling pathway through Dishevelled. (285 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

Mu-En Lee focuses on Heme oxygenase, Pharmacology, Vasodilation, Heme and Dishevelled. His biological study spans a wide range of topics, including Internal medicine, Renovascular hypertension, Blood pressure and Pathology. His Pharmacology research includes elements of Cell growth, Genetically modified mouse, Transgene and Reperfusion injury, Ischemia.

The concepts of his Vasodilation study are interwoven with issues in Vascular smooth muscle, HMOX1, Nitric oxide, Vasoconstriction and In vivo. His Heme study incorporates themes from Oxidative stress, Anesthesia, Hypoxia, Bilirubin and Kidney. As part of his Cell biology and Frizzled and Dishevelled studies, Mu-En Lee is studying Dishevelled.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Promotion of vascular smooth muscle cell growth by homocysteine: a link to atherosclerosis

J C Tsai;M A Perrella;M Yoshizumi;C M Hsieh.
Proceedings of the National Academy of Sciences of the United States of America (1994)

1231 Citations

Tumor necrosis factor downregulates an endothelial nitric oxide synthase mRNA by shortening its half-life.

Masao Yoshizumi;Mark A. Perrella;John C. Burnett;Mu En Lee.
Circulation Research (1993)

977 Citations

SMOOTH MUSCLE CELL-DERIVED CARBON MONOXIDE IS A REGULATOR OF VASCULAR CGMP

Toshisuke Morita;Mark A. Perrella;Mu-En Lee;Stella Kourembanas.
Proceedings of the National Academy of Sciences of the United States of America (1995)

909 Citations

Heme oxygenase-1 protects against vascular constriction and proliferation.

Henricus J. Duckers;Manfred Boehm;Andrea L. True;Shaw Fang Yet.
Nature Medicine (2001)

727 Citations

Cardiac-Specific Expression of Heme Oxygenase-1 Protects Against Ischemia and Reperfusion Injury in Transgenic Mice

Shaw Fang Yet;Rong Tian;Matthew D. Layne;Zhi Yuan Wang.
Circulation Research (2001)

546 Citations

Hypoxia induces severe right ventricular dilatation and infarction in heme oxygenase-1 null mice.

Shaw-Fang Yet;Mark A. Perrella;Matthew D. Layne;Chung-Ming Hsieh.
Journal of Clinical Investigation (1999)

483 Citations

Induction of Vascular Endothelial Growth Factor Gene Expression by Interleukin-1 β in Rat Aortic Smooth Muscle Cells (∗)

Jian Li;Mark A. Perrella;Mark A. Perrella;Jer-Chia Tsai;Shaw-Fang Yet.
Journal of Biological Chemistry (1995)

477 Citations

Akt participation in the Wnt signaling pathway through Dishevelled.

Shinya Fukumoto;Chung-Ming Hsieh;Koji Maemura;Matthew D. Layne.
Journal of Biological Chemistry (2001)

414 Citations

Cloning of the GATA-binding protein that regulates endothelin-1 gene expression in endothelial cells.

Mu-En Lee;D. H. Temizer;J. A. Clifford;T. Quertermous.
Journal of Biological Chemistry (1991)

328 Citations

Inhibition of Growth and p21ras Methylation in Vascular Endothelial Cells by Homocysteine but Not Cysteine

Hong Wang;Masao Yoshizumi;Kaihua Lai;Jer-Chia Tsai.
Journal of Biological Chemistry (1997)

319 Citations

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