His main research concerns Retina, Retinal degeneration, Retinal, Cell biology and Retinal pigment epithelium. His study in Retina is interdisciplinary in nature, drawing from both Neurotrophic factors, Ciliary neurotrophic factor, Basic fibroblast growth factor and Anatomy. His research integrates issues of Photoreceptor cell, Rhodopsin, Genetic enhancement and Retinitis pigmentosa in his study of Retinal degeneration.
His Rhodopsin study combines topics in areas such as Molecular biology and Visual phototransduction. His study in the field of Erg and Electroretinography is also linked to topics like Adeno-associated virus. In his research on the topic of Cell biology, Regulator, Transgene, Cell culture, Opsin and Signal transduction is strongly related with Apoptosis.
Matthew M. LaVail mostly deals with Retinal degeneration, Cell biology, Retina, Retinal and Molecular biology. His Retinal degeneration research integrates issues from Electroretinography, Degeneration, Retinitis pigmentosa, Photoreceptor cell and Rhodopsin. His work in Cell biology covers topics such as Ciliary neurotrophic factor which are related to areas like Basic fibroblast growth factor and Glial fibrillary acidic protein.
The Retina study which covers Neurotrophic factors that intersects with Endocrinology. His Retinal research is multidisciplinary, relying on both Genetic enhancement and Pathology. His studies deal with areas such as Gene expression and Transgene as well as Molecular biology.
His main research concerns Retinal degeneration, Cell biology, Retinal, Rhodopsin and Retinitis pigmentosa. Retina and Genetics are the two main areas of interest in his Retinal degeneration studies. His research on Retina focuses in particular on Disc shedding.
His Cell biology study integrates concerns from other disciplines, such as Apoptosis, Ceramide and Programmed cell death. His studies examine the connections between Retinal and genetics, as well as such issues in Neuroscience, with regards to Internal medicine, Endocrinology and Regeneration. His study in Rhodopsin is interdisciplinary in nature, drawing from both Mutant, Endoplasmic-reticulum-associated protein degradation, Photoreceptor cell, Transgenic Rats and Degenerative disease.
His primary scientific interests are in Retinal, Retinal degeneration, Cell biology, Retinitis pigmentosa and Molecular biology. Retinal is closely attributed to Retina in his research. His work in the fields of Retinal pigment epithelium overlaps with other areas such as C-Mer Tyrosine Kinase.
His work in Retinal degeneration addresses issues such as Rhodopsin, which are connected to fields such as Photoreceptor cell, Degenerative Disorder and Tissue Degeneration. In his study, which falls under the umbrella issue of Cell biology, Protein kinase B, Sirolimus, PI3K/AKT/mTOR pathway and Cancer research is strongly linked to Programmed cell death. His Molecular biology research is multidisciplinary, incorporating elements of Gene expression and Outer nuclear layer.
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IRE1 Signaling Affects Cell Fate During the Unfolded Protein Response
Jonathan H. Lin;Han Li;Douglas Yasumura;Hannah R. Cohen.
Mutation of the receptor tyrosine kinase gene Mertk in the retinal dystrophic RCS rat
Patricia M. D’Cruz;Douglas Yasumura;Jessica Weir;Michael T. Matthes.
Human Molecular Genetics (2000)
Retrograde Axonal Transport in the Central Nervous System
Jennifer H. Lavail;Matthew M. Lavail.
Photoreceptor degeneration in inherited retinal dystrophy delayed by basic fibroblast growth factor
Ella G. Faktorovich;Roy H. Steinberg;Douglas Yasumura;Michael T. Matthes.
Multiple growth factors, cytokines, and neurotrophins rescue photoreceptors from the damaging effects of constant light.
Matthew M. Lavail;Kazuhiko Unoki;Douglas Yasumura;Michael T. Matthes.
Proceedings of the National Academy of Sciences of the United States of America (1992)
Rod outer segment disk shedding in rat retina: relationship to cyclic lighting
Matthew M. LaVail.
Rods and cones in the mouse retina. I. Structural analysis using light and electron microscopy
Louvenia D. Carter-Dawson;Matthew M. Lavail;Matthew M. Lavail.
The Journal of Comparative Neurology (1979)
The retrograde intraaxonal transport of horseradish peroxidase in the chick visual system: a light and electron microscopic study.
Jennifer H. LaVail;Matthew M. LaVail.
The Journal of Comparative Neurology (1974)
Protection of mouse photoreceptors by survival factors in retinal degenerations.
Matthew M. LaVail;Douglas Yasumura;Michael T. Matthes;Cathy Lau-Villacorta.
Investigative Ophthalmology & Visual Science (1998)
Inherited retinal dystrophy: primary defect in pigment epithelium determined with experimental rat chimeras
Richard J. Mullen;Matthew M. LaVail.
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