Mary C. Nakamura mainly investigates Cell biology, Receptor, Immune system, Immunology and Syk. Mary C. Nakamura works mostly in the field of Cell biology, limiting it down to concerns involving ZAP70 and, occasionally, B-cell receptor. His research integrates issues of Myeloid, Cell culture, Transferrin and In vitro in his study of Receptor.
His Immune system research is multidisciplinary, incorporating perspectives in Inflammatory bowel disease and Arthritis. Many of his studies involve connections with topics such as Signal transduction and Immunology. The Cancer research study combines topics in areas such as Osteoclast and Bone resorption.
His primary areas of study are Cell biology, Immunology, Receptor, Osteoclast and Inflammation. His Cell biology research is multidisciplinary, incorporating elements of Immune receptor, Lymphokine-activated killer cell, Natural killer cell, TREM2 and Major histocompatibility complex. His Receptor study integrates concerns from other disciplines, such as Molecular biology, Lysis and MHC class I.
Mary C. Nakamura interconnects Endocrinology, Bone remodeling, Bone resorption and RANKL in the investigation of issues within Osteoclast. Mary C. Nakamura has researched RANKL in several fields, including Cancer research and Signal transduction. His Inflammation research also works with subjects such as
His primary areas of study are Cancer research, Immunology, Inflammation, Lung and Bone healing. His research on Cancer research also deals with topics like
His Lung research is multidisciplinary, incorporating perspectives in NKG2D, Innate immune system and Cell. In his study, which falls under the umbrella issue of Bioinformatics, Immune system is strongly linked to Inflammatory response. As part of his studies on Cell biology, Mary C. Nakamura often connects relevant subjects like TREM2.
Mary C. Nakamura mainly focuses on Osteoimmunology, Bone healing, Extramural, Neuroscience and Energy metabolism. His work carried out in the field of Bone healing brings together such families of science as Wnt signaling pathway, Nuclear localization sequence, Angiogenesis and Beta. He merges Extramural with Integrated systems in his research.
His Cartilage research incorporates Infiltration, Transcriptome, Pathology, Macrophage and Age related. His work on Inflammation expands to the thematically related Infiltration. Mary C. Nakamura has included themes like Tumor necrosis factor alpha and Psoriatic arthritis, Arthritis in his Inflammation study.
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The immunomodulatory adapter proteins DAP12 and Fc receptor γ-chain (FcRγ) regulate development of functional osteoclasts through the Syk tyrosine kinase
Attila Mócsai;Mary Beth Humphrey;Jessica A. G. Van Ziffle;Yongmei Hu.
Proceedings of the National Academy of Sciences of the United States of America (2004)
A role for TREM2 ligands in the phagocytosis of apoptotic neuronal cells by microglia.
Christine L. Hsieh;Maya Koike;Steve C. Spusta;Erene C. Niemi.
Journal of Neurochemistry (2009)
Cutting Edge: Inhibition of TLR and FcR Responses in Macrophages by Triggering Receptor Expressed on Myeloid Cells (TREM)-2 and DAP12
Jessica A. Hamerman;Jessica R. Jarjoura;Mary Beth Humphrey;Mary C. Nakamura.
Journal of Immunology (2006)
Binding and uptake of H-ferritin are mediated by human transferrin receptor-1
Li Li;Celia J. Fang;James C. Ryan;Eréne C. Niemi.
Proceedings of the National Academy of Sciences of the United States of America (2010)
Glucocorticoid excess in mice results in early activation of osteoclastogenesis and adipogenesis and prolonged suppression of osteogenesis: a longitudinal study of gene expression in bone tissue from glucocorticoid-treated mice.
Wei Yao;Zhiqiang Cheng;Cheryl Busse;Aaron Pham.
Arthritis & Rheumatism (2008)
Triggering Receptor Expressed on Myeloid Cells 2 (TREM2) Deficiency Attenuates Phagocytic Activities of Microglia and Exacerbates Ischemic Damage in Experimental Stroke
Masahito Kawabori;Rachid Kacimi;Tiina Kauppinen;Cyrus Calosing.
The Journal of Neuroscience (2015)
Mouse Ly-49A Interrupts Early Signaling Events in Natural Killer Cell Cytotoxicity and Functionally Associates with the SHP-1 Tyrosine Phosphatase
Mary C. Nakamura;Eréne C. Niemi;Mark J. Fisher;Leonard D. Shultz.
Journal of Experimental Medicine (1997)
Role of ITAM-containing adapter proteins and their receptors in the immune system and bone.
Mary Beth Humphrey;Lewis L. Lanier;Mary C. Nakamura;Mary C. Nakamura.
Immunological Reviews (2005)
TIM-2 is expressed on B cells and in liver and kidney and is a receptor for H-ferritin endocytosis
Thomas T. Chen;Li Li;Dong-Hui Chung;Christopher D.C. Allen.
Journal of Experimental Medicine (2005)
DAP12-mediated signal transduction in natural killer cells. A dominant role for the Syk protein-tyrosine kinase.
Daniel W. McVicar;Lynn S. Taylor;Pierre Gosselin;Jami Willette-Brown.
Journal of Biological Chemistry (1998)
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