World's Best Scientists 2026 revealed!
Makoto Michikawa

Makoto Michikawa

D-Index & Metrics

Biology and Biochemistry

D-Index
52
Citations
9639
World Ranking
16697
National Ranking
1195

Makoto Michikawa publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Makoto Michikawa sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 186 publications — 44th percentile

44% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Makoto Michikawa D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Makoto Michikawa sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 52 D-Index — 16th percentile

16% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Makoto Michikawa is affiliated with Nagoya City University in Japan and has an extensive research portfolio primarily focused on medicine and neuroscience. Their work spans several interrelated fields such as physiology, neurology, molecular biology, biological psychiatry, and cellular and molecular neuroscience.

Their main research topics center on Alzheimer's disease research and treatments, with significant contributions to understanding tryptophan's role in brain disorders, neuroinflammation and neurodegeneration mechanisms, dementia and cognitive impairment, gut microbiota and health, neurological disease mechanisms and treatments, as well as oral microbiology and periodontitis research.

Some of their recent publications include:

  • Japan-Multimodal Intervention Trial for the Prevention of Dementia: A randomized controlled trial, 2024, Alzheimer's & Dementia
  • Probiotic Bifidobacterium breve MCC1274 Mitigates Alzheimer's Disease-Related Pathologies in Wild-Type Mice, 2022, Nutrients
  • Cholesterol Regulates Exosome Release in Cultured Astrocytes, 2021, Frontiers in Immunology
  • Oral dysfunctions and cognitive impairment/dementia, 2020, Journal of Neuroscience Research
  • Current Biomarkers for Alzheimer's Disease: From CSF to Blood, 2020, Journal of Personalized Medicine

Throughout their career, Michikawa has frequently published in scientific journals such as the Journal of Alzheimer's Disease, Alzheimer's & Dementia, Nutrients, the International Journal of Molecular Sciences, and Frontiers in Aging Neuroscience. These venues reflect their focus on neurodegenerative diseases and related biological processes.

Collaborations have been an important aspect of their research activities. Frequent co-authors include Mona Abdelhamid, Chunyu Zhou, Cha-Gyun Jung, Kun Zou, and Tomohisa Nakamura. These partnerships suggest a multidisciplinary approach to tackling complex neurological conditions, particularly Alzheimer's disease.

Best Publications

  • A Novel Function of Monomeric Amyloid β-Protein Serving as an Antioxidant Molecule against Metal-Induced Oxidative Damage

    Kun Zou;Jian-Sheng Gong;Katsuhiko Yanagisawa;Makoto Michikawa

  • Apolipoprotein E regulates the integrity of tight junctions in an isoform-dependent manner in an in vitro blood-brain barrier model.

    Kazuchika Nishitsuji;Takashi Hosono;Toshiyuki Nakamura;Guojun Bu

  • A Seed for Alzheimer Amyloid in the Brain

    Hideki Hayashi;Nobuyuki Kimura;Haruyasu Yamaguchi;Kazuhiro Hasegawa

  • Apolipoprotein E exhibits isoform-specific promotion of lipid efflux from astrocytes and neurons in culture.

    Makoto Michikawa;Qi‐Wen Fan;Ichiro Isobe;Katsuhiko Yanagisawa

  • Apolipoprotein E (ApoE) Isoform-dependent Lipid Release from Astrocytes Prepared from Human ApoE3 and ApoE4 Knock-in Mice

    Jian Sheng Gong;Mariko Kobayashi;Hideki Hayashi;Kun Zou

  • Altered Cholesterol Metabolism in Niemann-Pick Type C1 Mouse Brains Affects Mitochondrial Function

    Wenxin Yu;Jian-Sheng Gong;Mihee Ko;William S. Garver

  • Midkine inhibits caspase-dependent apoptosis via the activation of mitogen-activated protein kinase and phosphatidylinositol 3-kinase in cultured neurons.

    Owada K;Sanjo N;Kobayashi T;Mizusawa H

  • Retinoic acid responsive gene product, midkine, has neurotrophic functions for mouse spinal cord and dorsal root ganglion neurons in culture.

    M. Michikawa;S. Kikuchi;H. Muramatsu;T. Muramatsu

  • Angiotensin-Converting Enzyme Converts Amyloid β-Protein 1–42 (Aβ1–42) to Aβ1–40, and Its Inhibition Enhances Brain Aβ Deposition

    Kun Zou;Haruyasu Yamaguchi;Hiroyasu Akatsu;Takaaki Sakamoto

  • Amyloid β-protein (Aβ)1–40 protects neurons from damage induced by Aβ1–42 in culture and in rat brain

    Kun Zou;Daesung Kim;Atsuko Kakio;Kyunghee Byun

  • Periodontitis induced by bacterial infection exacerbates features of Alzheimer’s disease in transgenic mice

    Naoyuki Ishida;Yuichi Ishihara;Kazuto Ishida;Hiroyuki Tada

  • A Novel Action of Alzheimer's Amyloid β-Protein (Aβ): Oligomeric Aβ Promotes Lipid Release

    Makoto Michikawa;Jian Sheng Gong;Qi Wen Fan;Naoya Sawamura

  • R-spondin, a novel gene with thrombospondin type 1 domain, was expressed in the dorsal neural tube and affected in Wnts mutants.

    Tomoyuki Kamata;Ken-ichi Katsube;Makoto Michikawa;Masahito Yamada

  • Inhibition of cholesterol production but not of nonsterol isoprenoid products induces neuronal cell death.

    Makoto Michikawa;Katsuhiko Yanagisawa

  • Cholesterol-dependent modulation of tau phosphorylation in cultured neurons.

    Qi-Wen Fan;Wei Yu;Takao Senda;Katsuhiko Yanagisawa

  • Cholesterol-dependent generation of a seeding amyloid beta-protein in cell culture.

    Tetsuya Mizuno;Makoto Nakata;Hironobu Naiki;Makoto Michikawa

  • Cholesterol paradox: is high total or low HDL cholesterol level a risk for Alzheimer's disease?

    Makoto Michikawa

  • Apolipoprotein E4 (1-272) fragment is associated with mitochondrial proteins and affects mitochondrial function in neuronal cells.

    Toshiyuki Nakamura;Atsushi Watanabe;Takahiro Fujino;Takashi Hosono

  • Site-specific phosphorylation of tau accompanied by activation of mitogen-activated protein kinase (MAPK) in brains of Niemann-Pick type C mice.

    Naoya Sawamura;Jian Sheng Gong;William S. Garver;Randall A. Heidenreich

  • Cholesterol‐dependent modulation of dendrite outgrowth and microtubule stability in cultured neurons

    Qi Wen Fan;Wei Yu;Jian Sheng Gong;Kun Zou

Frequent Co-Authors

Katsuhiko Yanagisawa
Katsuhiko Yanagisawa Japan Society for the Promotion of Science
Seung U. Kim
Seung U. Kim University of British Columbia
Tetsuya Mizuno
Tetsuya Mizuno Nagoya University
Shinji Yokoyama
Shinji Yokoyama Chubu University
Toshiharu Suzuki
Toshiharu Suzuki Hokkaido University
Hidehiro Mizusawa
Hidehiro Mizusawa Tokyo Medical and Dental University
Takashi Muramatsu
Takashi Muramatsu Nagoya University
Noriyuki Matsukawa
Noriyuki Matsukawa Nagoya City University
James G. McLarnon
James G. McLarnon University of British Columbia
Tony Wyss-Coray
Tony Wyss-Coray Stanford University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Graduates in Biology and Biochemistry have numerous options for advancing into healthcare careers, including medical coding, billing, and health information management. One pathway is earning a cpc certification, which is widely valued in the healthcare industry for those specializing in coding.

Many students explore medical coding as it offers solid job security and a clear salary outlook. For detailed information, you can learn about medical.coder salary potential and growth prospects.

The demand for professionals in this sector remains strong. Those interested in the field may wonder, is medical billing and coding in demand? The answer is yes—opportunities continue to increase as the healthcare system grows and evolves.

Flexible learning options are available for those needing to balance work and study. Individuals seeking accredited and affordable programs should research health information management schools online to begin or advance their careers from anywhere.

Best Scientists Citing Makoto Michikawa

Trending Scientists

Recently Published Articles