Luca Laurenti

Best Publications

• Analysis of the chronic lymphocytic leukemia coding genome: role of NOTCH1 mutational activation

  Giulia Fabbri;Silvia Rasi;Davide Rossi;Vladimir A. Trifonov

  782
  Citations

• Integrated mutational and cytogenetic analysis identifies new prognostic subgroups in chronic lymphocytic leukemia

  Davide Rossi;Silvia Rasi;Valeria Spina;Alessio Bruscaggin

  601
  Citations

• Mutations of NOTCH1 are an independent predictor of survival in chronic lymphocytic leukemia

  Davide Rossi;Silvia Rasi;Giulia Fabbri;Valeria Spina

  564
  Citations

• The genetics of Richter syndrome reveals disease heterogeneity and predicts survival after transformation

  Davide Rossi;Valeria Spina;Clara Deambrogi;Silvia Rasi

  441
  Citations

• The Akt/Mcl-1 pathway plays a prominent role in mediating antiapoptotic signals downstream of the B-cell receptor in chronic lymphocytic leukemia B cells.

  Pablo G. Longo;Luca Laurenti;Stefania Gobessi;Simona Sica

  386
  Citations

• Sustained signaling through the B-cell receptor induces Mcl-1 and promotes survival of chronic lymphocytic leukemia B cells.

  Aleksandar Petlickovski;Luca Laurenti;Luca Laurenti;Xiaoping Li;Xiaoping Li;Sara Marietti;Sara Marietti

  329
  Citations

• ADAMTS13 and anti-ADAMTS13 antibodies as markers for recurrence of acquired thrombotic thrombocytopenic purpura during remission

  Flora Peyvandi;Silvia Lavoretano;Roberta Palla;Hendrik B. Feys

  307
  Citations

• COVID-19 severity and mortality in patients with chronic lymphocytic leukemia: a joint study by ERIC, the European Research Initiative on CLL, and CLL Campus.

  Lydia Scarfò;Thomas Chatzikonstantinou;Gian Matteo Rigolin;Giulia Quaresmini

  288
  Citations

• Bruton's tyrosine kinase (BTK) function is important to the development and expansion of chronic lymphocytic leukemia (CLL).

  Jennifer A. Woyach;Engin Bojnik;Amy S. Ruppert;Matthew R. Stefanovski

  269
  Citations

• Stereotyped B-Cell Receptor Is an Independent Risk Factor of Chronic Lymphocytic Leukemia Transformation to Richter Syndrome

  Davide Rossi;Valeria Spina;Michaela Cerri;Silvia Rasi

  263
  Citations

• Molecular prediction of durable remission after first-line fludarabine-cyclophosphamide-rituximab in chronic lymphocytic leukemia.

  Davide Rossi;Lodovico Terzi-di-Bergamo;Lorenzo De Paoli;Michaela Cerri

  257
  Citations

• Inhibition of constitutive and BCR-induced Syk activation downregulates Mcl-1 and induces apoptosis in chronic lymphocytic leukemia B cells.

  S Gobessi;L Laurenti;P G Longo;L Carsetti

  246
  Citations

• ZAP-70 enhances B-cell–receptor signaling despite absent or inefficient tyrosine kinase activation in chronic lymphocytic leukemia and lymphoma B cells

  Stefania Gobessi;Luca Laurenti;Pablo G. Longo;Simona Sica

  227
  Citations

• Nicotinamide blocks proliferation and induces apoptosis of chronic lymphocytic leukemia cells through activation of the p53/miR-34a/SIRT1 tumor suppressor network.

  Valentina Audrito;Tiziana Vaisitti;Davide Rossi;Daniela Gottardi

  217
  Citations

• Preponderance of methylenetetrahydrofolate reductase C677T homozygosity among leukemia patients intolerant to methotrexate

  P. Chiusolo;G. Reddiconto;I. Casorelli;L. Laurenti

  213
  Citations

• The Akt signaling pathway determines the different proliferative capacity of chronic lymphocytic leukemia B-cells from patients with progressive and stable disease.

  P G Longo;L Laurenti;S Gobessi;A Petlickovski

  187
  Citations

• The Syk inhibitor fostamatinib disodium (R788) inhibits tumor growth in the Eμ- TCL1 transgenic mouse model of CLL by blocking antigen-dependent B-cell receptor signaling

  Mirza Suljagic;Pablo G. Longo;Sara Bennardo;Emerald Perlas

  182
  Citations

• Regulatory T-cell number is increased in chronic lymphocytic leukemia patients and correlates with progressive disease

  Giovanni D'Arena;Luca Laurenti;Maria Marta Minervini;Silvia Deaglio

  171
  Citations

• CD73-generated extracellular adenosine in chronic lymphocytic leukemia creates local conditions counteracting drug-induced cell death.

  Sara Serra;Alberto L. Horenstein;Tiziana Vaisitti;Davide Brusa

  167
  Citations

• Association between molecular lesions and specific B-cell receptor subsets in chronic lymphocytic leukemia

  Davide Rossi;Valeria Spina;Riccardo Bomben;Silvia Rasi

  158
  Citations